B4SCT5 (B4SCT5_PELPB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ACF42769.1

Gene names

Ordered Locus Names:

Ppha_0443

Organism

Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1) [Complete proteome] [HAMAP]

Taxonomic identifier

324925 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Pelodictyon

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4SCT5 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 1C9FBF67A7C94906	FASTA	380	42,759
	10 20 30 40 50 60 MSKKLFVLAG ELSGDMHAAG VITELLKARP ELKVFGIGGE KLRTLGAELL YDTAQMSIMG 70 80 90 100 110 120 FLDVLKHAGF LRRVIRELKE AIRREKPQAA FLVDYPGMNL MMARFFHQLG IPVIYYISPQ 130 140 150 160 170 180 VWAWKEGRVK AIRRDVDRLL VIFDFEVEFF RRHGINAEFV GHPVIEQLAE LSLPSRELFV 190 200 210 220 230 240 QRYNLAPDTL LIGLLPGSRK QEIAHILPEM LKAARLLSQN YRVVFLFGRA PHLDEEVYHA 250 260 270 280 290 300 WSAYPDLSVI NCSAYEVMQY SDLALVTSGT ATLESLCFGV PMVVVYRTGW LNYLIGRQLV 310 320 330 340 350 360 KLTSISLANI VAKGLGSSER AVPELIQHEA SGTEIYQTAC TILDDPEKAG TMRRELLAAR 370 380 ERLASDSPSH KIAAILQEYL

References

[1]

"Complete sequence of Pelodictyon phaeoclathratiforme BU-1." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F. , Overmann J., Bryant D.A., Richardson P. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 5477 / BU-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001110 Genomic DNA. Translation: ACF42769.1.
RefSeq	YP_002017386.1. NC_011060.1.
3D structure databases
ProteinModelPortal	B4SCT5.
ModBase	Search...
Protein-protein interaction databases
STRING	B4SCT5.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6462202.
GenomeReviews	Gene locus Ppha_0443 in contig CP001110_GR.
KEGG	pph:Ppha_0443.
PATRIC	22901314. VBIPelPha134556_0450.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
ProtClustDB	CLSK637261.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B4SCT5_PELPB

Accession

Primary (citable) accession number: B4SCT5

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)