B4S935 (B4S935_PROA2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377

Gene names

Name:	dnaA HAMAP MF_00377
Ordered Locus Names:	Paes_0001

Organism

Prosthecochloris aestuarii (strain DSM 271 / SK 413) [Complete proteome] [HAMAP] EMBL ACF45067.1

Taxonomic identifier

290512 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Prosthecochloris

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377
Subcellular location	Cytoplasm By similarity HAMAP MF_00377.
Sequence similarities	Belongs to the DnaA family. HAMAP MF_00377

Ontologies

Keywords
Biological process	DNA replication HAMAP MF_00377
Cellular component	Cytoplasm HAMAP MF_00377
Ligand	ATP-binding HAMAP MF_00377 DNA-binding HAMAP MF_00377 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA-dependent DNA replication initiation Inferred from electronic annotation. Source: HAMAP regulation of DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA replication origin binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	194 – 201	8	ATP By similarity HAMAP MF_00377

Sequences

	Sequence		Length	Mass (Da)
	B4S935 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 381B1A592E68B485	FASTA	492	55,815
	10 20 30 40 50 60 MPYTSPQDIL QTRPEAHPVK AGFAQKVWDA CLEIIKEKIN NQAFKTWFTP ITPLNFSDNE 70 80 90 100 110 120 LTIEVPSQFF YEWIEENYSR YVKEALKEII GAEGKLMYSI VMDKSQGHPV TIELPHQNIA 130 140 150 160 170 180 KSAEPPASTI PSPPQSADRE RFEKNRIKFE SHLNPKYTFS SLIRGDCNSL AFAASKSVAQ 190 200 210 220 230 240 NPGQNAFNPL VIYGGVGLGK THMMQAIGNQ VRENCISEYV LYVSSEKFAI DFVNAIQNGN 250 260 270 280 290 300 IQEFSSFYRK IDVLIIDDIQ FFAGKEKTQE EIFHIFNTLH QSNKQIILSS DRPIKEIKGI 310 320 330 340 350 360 EDRLISRFNW GLSVDLQPPD YETRKAIIQS KLEQNGVNLD STIVDFIATN VTQNVRELEG 370 380 390 400 410 420 CIVKLLAAHS LFNQEIDLAF TKSTLKDIIR IQSKQLTLET IEKAVCSYFS ITPNDLKGKS 430 440 450 460 470 480 KKKEIATGRQ IAMYLSKELT DSSLKTIGLH FGGRDHSTVI HGCNTVSKKM EQSMEIRNTI 490 EELKKRIEIM SM

References

[1]

"Complete sequence of chromosome of Prosthecochloris aestuarii DSM 271." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Liu Z., Li T., Zhao F. , Overmann J., Bryant D.A., Richardson P. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 271 / SK 413.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001108 Genomic DNA. Translation: ACF45067.1.
RefSeq	YP_002014714.1. NC_011059.1.
3D structure databases
ProteinModelPortal	B4S935.
ModBase	Search...
Protein-protein interaction databases
STRING	B4S935.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6459636.
GenomeReviews	Gene locus Paes_0001 in contig CP001108_GR.
KEGG	paa:Paes_0001.
PATRIC	23039578. VBIProAes37017_0001.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG695666.
OMA	CHTLNAL.
ProtClustDB	PRK00149.
Family and domain databases
HAMAP	MF_00377. DnaA_bact. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001957. Chromosome_initiator_DnaA. IPR020591. Chromosome_initiator_DnaA-like. IPR018312. Chromosome_initiator_DnaA_CS. IPR013159. DnaA_C. IPR013317. DnaA_Hda. IPR010921. Trp_repressor/repl_initiator. [Graphical view]
Gene3D	G3DSA:1.10.1750.10. DnaA_C. 1 hit.
KO	K02313.
Pfam	PF00308. Bac_DnaA. 1 hit. PF08299. Bac_DnaA_C. 1 hit. [Graphical view]
PRINTS	PR00051. DNAA.
SMART	SM00382. AAA. 1 hit. SM00760. Bac_DnaA_C. 1 hit. [Graphical view]
SUPFAM	SSF48295. Trp_repress_rep. 1 hit.
TIGRFAMs	TIGR00362. DnaA. 1 hit.
PROSITE	PS01008. DNAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B4S935_PROA2

Accession

Primary (citable) accession number: B4S935

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)