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B4S7P9 (ARLY_PROA2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Argininosuccinate lyase
Short name=ASAL
EC=4.3.2.1
Alternative name(s):
Arginosuccinase
Gene names
Name:argH
Ordered Locus Names:Paes_1047
OrganismProsthecochloris aestuarii (strain DSM 271 / SK 413) [Complete proteome] [HAMAP]
Taxonomic identifier290512 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Prosthecochloris

Protein attributes

Sequence length460 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006

Subcellular location

Cytoplasm By similarity HAMAP MF_00006.

Sequence similarities

Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Arginine biosynthesis
   Cellular componentCytoplasm
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine biosynthetic process via ornithine

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionargininosuccinate lyase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 460460Argininosuccinate lyase HAMAP MF_00006
PRO_1000089100

Sequences

Sequence LengthMass (Da)Tools
B4S7P9 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 15F9B04D828E51BC

FASTA46052,190
        10         20         30         40         50         60 
MSKKKELLWQ SRFSEPFDRE ALLFSSSVDV DKELYQEDIT GSIAHVTMLS EEAIIPAEEA 

        70         80         90        100        110        120 
RLIIEGLQEI EEEISTGSLV PHWEDEDIHT VIENRLKEKI GPIAGKIHSG RSRNDQVATD 

       130        140        150        160        170        180 
TRLYLKRSIE EIRQALKELK TVLVDKAEAY RRTIIFGYTH LQRAQPISAG HYYLAYFNMF 

       190        200        210        220        230        240 
DRDNQRLQDL YKRVDISPLG AAAFAGSTLA LNAERSRDLL EFEGLFHNSI DAVSDRDIII 

       250        260        270        280        290        300 
EFVSACSIIM MHLSRFAEDL ILWSSYEFNY LEISDAFATG SSIMPQKKNA DIAELVRGKT 

       310        320        330        340        350        360 
GRVYGDLMAM LTIMKGLPLS YNRDMQEDKP PLFDASKTTR SSVRIFTKML ENTSIKENRL 

       370        380        390        400        410        420 
SSLVAKDLSL ATEIAEYLVQ KNMPFRDAHR VTGKIVSHVI ESGTTLPDMT LETYRTFSDL 

       430        440        450        460 
FDEDLYDALK PEASVNAKKT HGSTSFASVE EQIVSARTRI

« Hide

References

[1]"Complete sequence of chromosome of Prosthecochloris aestuarii DSM 271."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Liu Z., Li T., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 271 / SK 413.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001108 Genomic DNA. Translation: ACF46086.1.
RefSeqYP_002015733.1. NC_011059.1.

3D structure databases

ProteinModelPortalB4S7P9.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4S7P9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6459898.
GenomeReviewsGene locus Paes_1047 in contig CP001108_GR.
KEGGpaa:Paes_1047.
PATRIC23041848. VBIProAes37017_1101.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG539632.
OMAEDIHTVI.
ProtClustDBPRK00855.

Family and domain databases

HAMAPMF_00006. Arg_succ_lyase.
[Tree]
InterProIPR009049. Argininosuccinate_lyase.
IPR003031. D_crystallin.
IPR000362. Fumarate_lyase.
IPR020557. Fumarate_lyase_CS.
IPR008948. L-Aspartase-like.
IPR024083. L-Aspartase-like_N.
IPR022761. Lyase1_N.
[Graphical view]
Gene3DG3DSA:1.10.275.10. G3DSA:1.10.275.10. 2 hits.
KOK01755.
PANTHERPTHR11444:SF3. argH. 1 hit.
PfamPF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSPR00145. ARGSUCLYASE.
PR00149. FUMRATELYASE.
SUPFAMSSF48557. L-Aspartase-like. 1 hit.
TIGRFAMsTIGR00838. ArgH. 1 hit.
PROSITEPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARLY_PROA2
AccessionPrimary (citable) accession number: B4S7P9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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