B4S3S9 (B4S3S9_PROA2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Holo-[acyl-carrier-protein] synthase HAMAP MF_00101
Short name=Holo-ACP synthase HAMAP MF_00101
EC=2.7.8.7 HAMAP MF_00101

Alternative name(s):
4'-phosphopantetheinyl transferase AcpS HAMAP MF_00101

Gene names

Name:	acpS HAMAP MF_00101
Ordered Locus Names:	Paes_0218

Organism

Prosthecochloris aestuarii (strain DSM 271 / SK 413) [Complete proteome] [HAMAP] EMBL ACF45275.1

Taxonomic identifier

290512 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Prosthecochloris

Protein attributes

Sequence length	127 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity. HAMAP MF_00101
Catalytic activity	CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP MF_00101
Cofactor	Magnesium By similarity. HAMAP MF_00101
Subcellular location	Cytoplasm By similarity HAMAP MF_00101.
Sequence similarities	Belongs to the P-Pant transferase superfamily. AcpS family. HAMAP MF_00101

Ontologies

Keywords
Biological process	Fatty acid biosynthesis HAMAP MF_00101 Lipid synthesis
Cellular component	Cytoplasm HAMAP MF_00101
Ligand	Magnesium HAMAP MF_00101 Metal-binding HAMAP MF_00101
Molecular function	Transferase HAMAP MF_00101
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP macromolecule biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	holo-[acyl-carrier-protein] synthase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	14	1	Magnesium By similarity HAMAP MF_00101
	Metal binding	63	1	Magnesium By similarity HAMAP MF_00101

Sequences

	Sequence		Length	Mass (Da)
	B4S3S9 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 6E643B8867FF171C	FASTA	127	13,874
	10 20 30 40 50 60 MSQTMTSNRD IGVDIVDISR IKASFEKYGE SFLQRVLTGN EIRHCRKKPD MMASVAARFA 70 80 90 100 110 120 AKEALSKALG RGISEAFGWQ SVEVLNDGFG RPVVNVLDKS LGIEASSIKI SLSHDGPFAV AFVLLDR

References

[1]

"Complete sequence of chromosome of Prosthecochloris aestuarii DSM 271." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Liu Z., Li T., Zhao F. , Overmann J., Bryant D.A., Richardson P. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 271 / SK 413.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001108 Genomic DNA. Translation: ACF45275.1.
RefSeq	YP_002014922.1. NC_011059.1.
3D structure databases
ProteinModelPortal	B4S3S9.
ModBase	Search...
Protein-protein interaction databases
STRING	B4S3S9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6460608.
GenomeReviews	Gene locus Paes_0218 in contig CP001108_GR.
KEGG	paa:Paes_0218.
PATRIC	23040048. VBIProAes37017_0228.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734479.
OMA	NSSAIAY.
ProtClustDB	CLSK2320681.
Family and domain databases
HAMAP	MF_00101. AcpS. [Tree]
InterPro	IPR008278. 4-PPantetheinyl_Trfase. IPR002582. ACPS. IPR004568. PPantethiene-prot_Trfase. [Graphical view]
Gene3D	G3DSA:3.90.470.20. G3DSA:3.90.470.20. 1 hit.
KO	K00997.
Pfam	PF01648. ACPS. 1 hit. [Graphical view]
ProDom	PD004282. PPantethiene-prot_Trfase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF56214. 4-PPT_transf. 1 hit.
TIGRFAMs	TIGR00516. AcpS. 1 hit. TIGR00556. Pantethn_trn. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B4S3S9_PROA2

Accession

Primary (citable) accession number: B4S3S9

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)