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B4S3H1 (UPPP_PROA2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Paes_1692
OrganismProsthecochloris aestuarii (strain DSM 271 / SK 413) [Complete proteome] [HAMAP]
Taxonomic identifier290512 [NCBI]
Taxonomic lineageBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeProsthecochloris

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 282282Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_1000197390

Regions

Transmembrane40 – 6021Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane117 – 13721Helical; Potential
Transmembrane158 – 17821Helical; Potential
Transmembrane193 – 21321Helical; Potential
Transmembrane231 – 25121Helical; Potential
Transmembrane258 – 27821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
B4S3H1 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: F699CAC632511579

FASTA28230,157
        10         20         30         40         50         60 
MSLFEAIILG IAQGLTEFLP ISSTAHLRIV PALAGWQDPG AAFTAIVQIG TLIAVLIYFF 

        70         80         90        100        110        120 
RDIVTISGAV IKGLMNASPL GTPDAKMGWM IAAGTIPIVV FGLLFKTEIE TSLRSLYWIS 

       130        140        150        160        170        180 
AALITLAIIL SLAEWLIKKR IAKGIEPKSM SDIRWKEALI IGLVQSIALI PGSSRSGVTI 

       190        200        210        220        230        240 
TGGLFMNLSR ETAARFSFLL SLPAVFAAGI YQLYKSWDSL MASTNDLVNL IVATLVAGIV 

       250        260        270        280 
GYASIAFLIT FLKQHSTAVF IIYRIALGLT ILALIATGNV QA 

« Hide

References

[1]"Complete sequence of chromosome of Prosthecochloris aestuarii DSM 271."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Liu Z., Li T., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 271 / SK 413.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001108 Genomic DNA. Translation: ACF46710.1.
RefSeqYP_002016357.1. NC_011059.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290512.Paes_1692.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACF46710; ACF46710; Paes_1692.
GeneID6459950.
KEGGpaa:Paes_1692.
PATRIC23043274. VBIProAes37017_1805.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAMEQINIG.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycPAES290512:GHUT-1737-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_PROA2
AccessionPrimary (citable) accession number: B4S3H1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families