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B4S3G5 (B4S3G5_PROA2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Paes_1686
OrganismProsthecochloris aestuarii (strain DSM 271 / SK 413) [Complete proteome] [HAMAP] EMBL ACF46704.1
Taxonomic identifier290512 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Prosthecochloris

Protein attributes

Sequence length659 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS005477

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS005477

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS005477

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS005477

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS005477

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
B4S3G5 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: BCC4F134929F7EA8

FASTA65971,960
        10         20         30         40         50         60 
MTKLPCFHET DAYRSLNTIN SPEDLKRFKP SELQQIADEC RSYLIDVIAE NGGHFASSLG 

        70         80         90        100        110        120 
VVELTVAMHY VFDSPKDKFI WDVGHQAYIH KILTGRRDLM HTNRRFNGLA GFPKIHESRH 

       130        140        150        160        170        180 
DAFGTGHAST SISAAAGMAA ARDLEGGNEK IIAVIGDGSM TGGMAFEAMN HLGDLKSDVL 

       190        200        210        220        230        240 
VILNDNQMAI SPSTGGLRDY LINISLNKTY NKLRQFVWNS LSLINNDVGD AAKTAIHKIE 

       250        260        270        280        290        300 
DGIKASLTPG AFFEALGFRY FGPIDGHNMD QLVKAMKEMQ ALPHPKLLHV ITKKGKGFLP 

       310        320        330        340        350        360 
AEQNQSAWHA HSGGFDRTTG ESLKPSQKKS PPKYQEIFGE ALTEIATNDR KIVGITAAMP 

       370        380        390        400        410        420 
SGTSLDIFQK AHPRRFYDVG IAEQHAVSFA AGLAAHGYKP VCAIYSTFLQ RAYDQLIHDV 

       430        440        450        460        470        480 
ALQNQHVIFA IDRAGLVGED GPTHHGSFDL SYLHPVPNMV IMAPKDGQEL RDMLYTALEH 

       490        500        510        520        530        540 
HHGPSAIRYP RGQAAAMELR KEFKAIAIGK GEIIREGNDI AILAIGSMVG HALQAAEILE 

       550        560        570        580        590        600 
AKGIDPLVAN MRFVKPLDTQ LLDTIASSHE KIVVIEENSV IGGLGSGIGD ALQKKGMKNK 

       610        620        630        640        650 
VFKIGLPDQF VTHGSMNELY SMLGLDRNGL AETVIKIYNG SSNAVNDSAQ TMIRTERLA

« Hide

References

[1]"Complete sequence of chromosome of Prosthecochloris aestuarii DSM 271."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Liu Z., Li T., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 271 / SK 413.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001108 Genomic DNA. Translation: ACF46704.1.
RefSeqYP_002016351.1. NC_011059.1.

3D structure databases

ProteinModelPortalB4S3G5.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4S3G5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6459451.
GenomeReviewsGene locus Paes_1686 in contig CP001108_GR.
KEGGpaa:Paes_1686.
PATRIC23043260. VBIProAes37017_1798.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG571647.
OMADPILYHG.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
PF00456. Transketolase_N. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4S3G5_PROA2
AccessionPrimary (citable) accession number: B4S3G5
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info