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B4S3F6

- B4S3F6_PROA2

UniProt

B4S3F6 - B4S3F6_PROA2

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Paes_1677

Organism
Prosthecochloris aestuarii (strain DSM 271 / SK 413)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei143 – 1431SubstrateUniRule annotation
    Sitei253 – 2531Critical for catalysisUniRule annotation
    Metal bindingi348 – 3481Magnesium or manganese
    Sitei418 – 4181Critical for catalysisUniRule annotation
    Binding sitei545 – 5451SubstrateUniRule annotation
    Metal bindingi546 – 5461Magnesium or manganese
    Metal bindingi550 – 5501Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciPAES290512:GHUT-1722-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Paes_1677Imported
    OrganismiProsthecochloris aestuarii (strain DSM 271 / SK 413)Imported
    Taxonomic identifieri290512 [NCBI]
    Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeProsthecochloris
    ProteomesiUP000002725: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi290512.Paes_1677.

    Structurei

    3D structure databases

    ProteinModelPortaliB4S3F6.
    SMRiB4S3F6. Positions 3-738.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni130 – 1378Substrate bindingUniRule annotation

    Phylogenomic databases

    eggNOGiCOG2838.
    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiYSMERAI.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4S3F6-1 [UniParc]FASTAAdd to Basket

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    MAKIIYTKID EAPALATYSL LPIIQAFTSG TGVEVETRDI SLAGRIIANF    50
    PDNLTPEQQI PDYLSELGEL AKTKEANIIK LPNISASIPQ LQAAIKELQS 100
    KGYNVPDYPE EPKNDAEKEI KVRYAKVLGS AVNPVLREGN SDRRAAASVK 150
    QYAQNNPHRL RAWESGSKAS VAYMESGDFY ETEKSATMNG ADSVRIEYVD 200
    GDGNVTVLKD SLSLLDGEVI DTSIMNVRKL RDFYAAQIER SKNDDMLLSL 250
    HLKATMMKVS DPIMFGHAVL VFYKDVFDKH GDTFKALGVN VNNGLGDVYA 300
    KIQSLPEDKR AEIEADIQAV YPSRPALAMV DSDKGITNLH VPNDIIIDAS 350
    MPVVIRDGGK MWGPDGELHD TTAMIPDRCY ATMYQEMIED CQKNGAYDVS 400
    TMGSVSNVGL MAQKAEEYGS HDKTFEAPGD GVIRVVDGSG KAMLEQVVET 450
    GDIYRMCQVK DAPIRDWVKL AVNRAKATGV PAVFWLDKER AHHVQLIEKV 500
    TAYLKEHDTE GLDIRIMSPV EAMRFSLERI RAGKDTISVT GNVLRDYLTD 550
    LFPILELGTS AKMLSIVPLM NGGGLFETGA GGSAPKHVQQ FLKEGHLRWD 600
    SLGEMLALGV SLEHLAAAFK NDKAQVLADT VDQAVGQYLE NRKSPSRKVN 650
    EIDNRGSHYY FALYWAQALA AQDKDQELKA KFAGIAESMA ASEAAIIDEL 700
    NAAQGSAVDV DGYFMPDDEK ASQAMRPSAT LNAIIDALK 739
    Length:739
    Mass (Da):81,028
    Last modified:September 23, 2008 - v1
    Checksum:iD26FC43C6D4E343F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001108 Genomic DNA. Translation: ACF46695.1.
    RefSeqiYP_002016342.1. NC_011059.1.

    Genome annotation databases

    EnsemblBacteriaiACF46695; ACF46695; Paes_1677.
    GeneIDi6460385.
    KEGGipaa:Paes_1677.
    PATRICi23043238. VBIProAes37017_1787.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001108 Genomic DNA. Translation: ACF46695.1 .
    RefSeqi YP_002016342.1. NC_011059.1.

    3D structure databases

    ProteinModelPortali B4S3F6.
    SMRi B4S3F6. Positions 3-738.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 290512.Paes_1677.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACF46695 ; ACF46695 ; Paes_1677 .
    GeneIDi 6460385.
    KEGGi paa:Paes_1677.
    PATRICi 23043238. VBIProAes37017_1787.

    Phylogenomic databases

    eggNOGi COG2838.
    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi YSMERAI.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci PAES290512:GHUT-1722-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Prosthecochloris aestuarii DSM 271."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Liu Z., Li T., Zhao F.
      , Overmann J., Bryant D.A., Richardson P.
      Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 271 / SK 413Imported.

    Entry informationi

    Entry nameiB4S3F6_PROA2
    AccessioniPrimary (citable) accession number: B4S3F6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3