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B4S3F6

- B4S3F6_PROA2

UniProt

B4S3F6 - B4S3F6_PROA2

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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene
Paes_1677
Organism
Prosthecochloris aestuarii (strain DSM 271 / SK 413)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei143 – 1431Substrate By similarityUniRule annotation
Sitei253 – 2531Critical for catalysis By similarityUniRule annotation
Metal bindingi348 – 3481Magnesium or manganese By similarityUniRule annotation
Sitei418 – 4181Critical for catalysis By similarityUniRule annotation
Binding sitei545 – 5451Substrate By similarityUniRule annotation
Metal bindingi546 – 5461Magnesium or manganese By similarityUniRule annotation
Metal bindingi550 – 5501Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPAES290512:GHUT-1722-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Paes_1677Imported
OrganismiProsthecochloris aestuarii (strain DSM 271 / SK 413)Imported
Taxonomic identifieri290512 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeProsthecochloris
ProteomesiUP000002725: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi290512.Paes_1677.

Structurei

3D structure databases

ProteinModelPortaliB4S3F6.
SMRiB4S3F6. Positions 3-738.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni130 – 1378Substrate binding By similarityUniRule annotation

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiYSMERAI.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

B4S3F6-1 [UniParc]FASTAAdd to Basket

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MAKIIYTKID EAPALATYSL LPIIQAFTSG TGVEVETRDI SLAGRIIANF    50
PDNLTPEQQI PDYLSELGEL AKTKEANIIK LPNISASIPQ LQAAIKELQS 100
KGYNVPDYPE EPKNDAEKEI KVRYAKVLGS AVNPVLREGN SDRRAAASVK 150
QYAQNNPHRL RAWESGSKAS VAYMESGDFY ETEKSATMNG ADSVRIEYVD 200
GDGNVTVLKD SLSLLDGEVI DTSIMNVRKL RDFYAAQIER SKNDDMLLSL 250
HLKATMMKVS DPIMFGHAVL VFYKDVFDKH GDTFKALGVN VNNGLGDVYA 300
KIQSLPEDKR AEIEADIQAV YPSRPALAMV DSDKGITNLH VPNDIIIDAS 350
MPVVIRDGGK MWGPDGELHD TTAMIPDRCY ATMYQEMIED CQKNGAYDVS 400
TMGSVSNVGL MAQKAEEYGS HDKTFEAPGD GVIRVVDGSG KAMLEQVVET 450
GDIYRMCQVK DAPIRDWVKL AVNRAKATGV PAVFWLDKER AHHVQLIEKV 500
TAYLKEHDTE GLDIRIMSPV EAMRFSLERI RAGKDTISVT GNVLRDYLTD 550
LFPILELGTS AKMLSIVPLM NGGGLFETGA GGSAPKHVQQ FLKEGHLRWD 600
SLGEMLALGV SLEHLAAAFK NDKAQVLADT VDQAVGQYLE NRKSPSRKVN 650
EIDNRGSHYY FALYWAQALA AQDKDQELKA KFAGIAESMA ASEAAIIDEL 700
NAAQGSAVDV DGYFMPDDEK ASQAMRPSAT LNAIIDALK 739
Length:739
Mass (Da):81,028
Last modified:September 23, 2008 - v1
Checksum:iD26FC43C6D4E343F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001108 Genomic DNA. Translation: ACF46695.1.
RefSeqiYP_002016342.1. NC_011059.1.

Genome annotation databases

EnsemblBacteriaiACF46695; ACF46695; Paes_1677.
GeneIDi6460385.
KEGGipaa:Paes_1677.
PATRICi23043238. VBIProAes37017_1787.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001108 Genomic DNA. Translation: ACF46695.1 .
RefSeqi YP_002016342.1. NC_011059.1.

3D structure databases

ProteinModelPortali B4S3F6.
SMRi B4S3F6. Positions 3-738.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290512.Paes_1677.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACF46695 ; ACF46695 ; Paes_1677 .
GeneIDi 6460385.
KEGGi paa:Paes_1677.
PATRICi 23043238. VBIProAes37017_1787.

Phylogenomic databases

eggNOGi COG2838.
HOGENOMi HOG000240860.
KOi K00031.
OMAi YSMERAI.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci PAES290512:GHUT-1722-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Prosthecochloris aestuarii DSM 271."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Liu Z., Li T., Zhao F.
    , Overmann J., Bryant D.A., Richardson P.
    Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 271 / SK 413.

Entry informationi

Entry nameiB4S3F6_PROA2
AccessioniPrimary (citable) accession number: B4S3F6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 9, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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