Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Catalase-peroxidase

Gene

katG

Organism
Prosthecochloris aestuarii (strain DSM 271 / SK 413)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.UniRule annotation

Catalytic activityi

Donor + H2O2 = oxidized donor + 2 H2O.UniRule annotation
2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

heme bUniRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei94 – 941Transition state stabilizerUniRule annotation
Active sitei98 – 981Proton acceptorUniRule annotation
Metal bindingi261 – 2611Iron (heme axial ligand)UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciPAES290512:GHUT-155-MONOMER.

Protein family/group databases

PeroxiBasei2534. PaeCP01.

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-peroxidaseUniRule annotation (EC:1.11.1.21UniRule annotation)
Short name:
CPUniRule annotation
Alternative name(s):
Peroxidase/catalaseUniRule annotation
Gene namesi
Name:katGUniRule annotation
Ordered Locus Names:Paes_0148
OrganismiProsthecochloris aestuarii (strain DSM 271 / SK 413)
Taxonomic identifieri290512 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeProsthecochloris
Proteomesi
  • UP000002725 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 732732Catalase-peroxidasePRO_0000354861Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Cross-linki97 ↔ 220Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-246)UniRule annotation
Cross-linki220 ↔ 246Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-97)UniRule annotation

Post-translational modificationi

The covalent Trp-Tyr-Met adduct is important for the catalase, but not the peroxidase activity of the enzyme.UniRule annotation

Proteomic databases

PRIDEiB4S3B3.

Interactioni

Subunit structurei

Homodimer or homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi290512.Paes_0148.

Structurei

3D structure databases

ProteinModelPortaliB4S3B3.
SMRiB4S3B3. Positions 20-732.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Peroxidase/catalase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
HOGENOMiHOG000218110.
KOiK03782.
OMAiTRWSNNF.
OrthoDBiPOG091H05R1.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4S3B3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEQSRCPVT GRTADSPATG SGLSNRDWWP NQLHLDMLHQ HSSLVNPMGE
60 70 80 90 100
GFRYKEEFGK LDLKEVKKDL YALMTDSQEW WPADYGHYGG LFIRMAWHSA
110 120 130 140 150
GTYRTSDGRG GGGTGNQRFA PLNSWPDNAN LDKARRLLWP IKQKYGKKIS
160 170 180 190 200
WADLMILAGN CALESMGFKT FGFGGGRVDI WEPEEDIYWG KEVEWLGNKR
210 220 230 240 250
YSGERDLENP LAAVQMGLIY VNPEGPDGKP DPVAAGRDIR ETFARMAMND
260 270 280 290 300
EETVALVAGG HTFGKCHGVG DPKLVGPEPE AADIEEQGLG WKSGYGIGKG
310 320 330 340 350
DETMTSGLEG AWTPDPIHWD MGYLGMLFRY EWELTKSPAG AWQWKPKDVA
360 370 380 390 400
EEDLAPAAHD PSKRVPTMMT TADLAMRMDP IYGPISQRYY EHPDQFADAF
410 420 430 440 450
ARAWFKLTHR DMGPHSRYLG AEVPAEELIW QDPVPALDHD LIDAEEIAEL
460 470 480 490 500
KKRLLASGLS IPELVSTAWA SASTFRGSDK RGGANGARIR LAPQKDWEVN
510 520 530 540 550
QPEQLQRVLH KLEEIRNTFN GEQSGNKQVS LADMIVLGGC AAVEEAAGKA
560 570 580 590 600
GTGVTVPFTP GRTDALQEQT DTESFSVLEP LADGFRNYMK KKYSVSAEEM
610 620 630 640 650
LVDRSQLLTL TAPEMTVLLG GLRVLGANFQ QSPHGVFTTQ PETLTNDYFV
660 670 680 690 700
NLLDMGTEWK PLSKEQDTFE GRDRKTGEPR WTATRVDLIF GSNSRLRAIA
710 720 730
EVYGSDDAQE KFVHDFVAAW DKVMNLDRFD LG
Length:732
Mass (Da):81,510
Last modified:September 23, 2008 - v1
Checksum:i3ED0316D308D412C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001108 Genomic DNA. Translation: ACF45207.1.
RefSeqiWP_012504744.1. NC_011059.1.

Genome annotation databases

EnsemblBacteriaiACF45207; ACF45207; Paes_0148.
KEGGipaa:Paes_0148.
PATRICi23039898. VBIProAes37017_0154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001108 Genomic DNA. Translation: ACF45207.1.
RefSeqiWP_012504744.1. NC_011059.1.

3D structure databases

ProteinModelPortaliB4S3B3.
SMRiB4S3B3. Positions 20-732.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290512.Paes_0148.

Protein family/group databases

PeroxiBasei2534. PaeCP01.

Proteomic databases

PRIDEiB4S3B3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACF45207; ACF45207; Paes_0148.
KEGGipaa:Paes_0148.
PATRICi23039898. VBIProAes37017_0154.

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
HOGENOMiHOG000218110.
KOiK03782.
OMAiTRWSNNF.
OrthoDBiPOG091H05R1.

Enzyme and pathway databases

BioCyciPAES290512:GHUT-155-MONOMER.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKATG_PROA2
AccessioniPrimary (citable) accession number: B4S3B3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: September 23, 2008
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.