Reviewed, UniProtKB/Swiss-Prot B4S278 (SYGA_ALTMD)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	MADE_00009

Organism

Alteromonas macleodii (strain DSM 17117 / Deep ecotype) [Complete proteome] [HAMAP]

Taxonomic identifier

314275 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Alteromonas

Protein attributes

Sequence length	301 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 301	301	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000101174

Sequences

	Sequence		Length	Mass (Da)
	B4S278-1 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 96157FDB023F1176	FASTA	301	34,512
	10 20 30 40 50 60 MQKYDIKTFQ GLILALQDYW ARQGCVIIQP LDMEVGAGTF HPMTFLRSLG PEPMSSAYVQ 70 80 90 100 110 120 PCRRPTDGRY GENPNRLQHY YQFQVMLKPS PDNIQELYLG SLKELGFDPL VHDIRFVEDN 130 140 150 160 170 180 WESPTLGAWG LGWEVWLNGM EVTQFTYFQQ VGGIECKPVT GEITYGLERL AMYVQGVDSI 190 200 210 220 230 240 YDLVWTDGPM GKVTYGDVFH QNEVEQSTYN FEHANVEALF RTFDECEAES KKLIENSLPL 250 260 270 280 290 300 PAYEQVMKAS HAFNLLDARH AISVTERQRY ILRVRTLAKA CAESYYQARE ALGFPLCNKE A

References

[1]

"Comparative genomics of two ecotypes of the marine planktonic copiotroph Alteromonas macleodii suggests alternative lifestyles associated with different kinds of particulate organic matter." Ivars-Martinez E., Martin-Cuadrado A.-B., D'Auria G., Mira A., Ferriera S., Johnson J., Friedman R., Rodriguez-Valera F. ISME J. 2:1194-1212(2008) [PubMed: 18670397] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001103 Genomic DNA. Translation: ACG64329.1.
RefSeq	YP_002124323.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6775586.
GenomeReviews	Gene locus MADE_00009 in contig CP001103_GR.
KEGG	amc:MADE_00009.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CRRPTDG.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_ALTMD

Accession

Primary (citable) accession number: B4S278

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	September 23, 2008
Last modified:	November 3, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)