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B4S0J5 (PSD_ALTMD) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:MADE_1002750
OrganismAlteromonas macleodii (strain DSM 17117 / Deep ecotype) [Complete proteome] [HAMAP]
Taxonomic identifier314275 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Alteromonas

Protein attributes

Sequence length325 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 252252Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000131334
Chain253 – 32573Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000131335

Sites

Site252 – 2532Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2531Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
B4S0J5 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: A075E6C94D907827

FASTA32535,872
        10         20         30         40         50         60 
MLDWLKVNLQ YVTPKHLLSR LVGKLAEAEM GSVTTFFIKL FIKQYNVDMT EALHEKPEHY 

        70         80         90        100        110        120 
RSFNKFFTRT LKPEARTIDE SDDVLIHAVD GTVSQFGDIR SDSIFQAKGH DFSLTTLLGG 

       130        140        150        160        170        180 
KPDVAAPFKN GKFATVYLAP RDYHRIHMPI EGTLTDMLYV PGELFSVNPL TAQNIPGLFA 

       190        200        210        220        230        240 
RNERVVALFD TPVGKMAMVL VGATIVASIE TVWAGTVTPP TGKTVQHWSY ETDSEAAVKL 

       250        260        270        280        290        300 
EKGAELGRFK LGSTIVVCFE KDMIDFEDIA PGMVTRLGEP MASKMSSQKA ITPEQTTETP 

       310        320 
VQASNEFDDN AGETKKDTPS EGADS

« Hide

References

[1]"Comparative genomics of two ecotypes of the marine planktonic copiotroph Alteromonas macleodii suggests alternative lifestyles associated with different kinds of particulate organic matter."
Ivars-Martinez E., Martin-Cuadrado A.-B., D'Auria G., Mira A., Ferriera S., Johnson J., Friedman R., Rodriguez-Valera F.
ISME J. 2:1194-1212(2008) [PubMed: 18670397] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17117 / Deep ecotype.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001103 Genomic DNA. Translation: AEA96699.1.
RefSeqYP_004425697.1. NC_011138.2.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB4S0J5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10555894.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG302256.
OMASMATVWH.
ProtClustDBPRK00044.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_ALTMD
AccessionPrimary (citable) accession number: B4S0J5
Secondary accession number(s): F2G7B9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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