Reviewed, UniProtKB/Swiss-Prot B4RZ25 (DCD_ALTMD)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	MADE_01987

Organism

Alteromonas macleodii (strain DSM 17117 / Deep ecotype) [Complete proteome] [HAMAP]

Taxonomic identifier

314275 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Alteromonas

Protein attributes

Sequence length	197 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 197	197	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000096405

Sequences

	Sequence		Length	Mass (Da)
	B4RZ25-1 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: E3325AF924AD9795	FASTA	197	21,777
	10 20 30 40 50 60 MRLCDRDIYQ HLQDGKIKID PTPDYDQISG VTVDIRLGNK FRVFEDHQAP FIDLSGPKAQ 70 80 90 100 110 120 VQEALDHVMS DEIELEEGKA FFLHPGELAL AITHESVTLP DNIVGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WSGNIVLEFY NSGKLPLALR PKMKIGALSF EVLSAPAEKP YNARVDAKYK 190 GQAGAVASRI SSDDQSK

References

[1]

"Comparative genomics of two ecotypes of the marine planktonic copiotroph Alteromonas macleodii suggests alternative lifestyles associated with different kinds of particulate organic matter." Ivars-Martinez E., Martin-Cuadrado A.-B., D'Auria G., Mira A., Ferriera S., Johnson J., Friedman R., Rodriguez-Valera F. ISME J. 2:1194-1212(2008) [PubMed: 18670397] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001103 Genomic DNA. Translation: ACG66291.1.
RefSeq	YP_002126285.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6775803.
GenomeReviews	Gene locus MADE_01987 in contig CP001103_GR.
KEGG	amc:MADE_01987.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GSRYQGQ.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. DeoxyUTP_pyroPase_dom. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_ALTMD

Accession

Primary (citable) accession number: B4RZ25

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	September 23, 2008
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)