Reviewed, UniProtKB/Swiss-Prot B4RXA8 (GLMM_ALTMD)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	MADE_01688

Organism

Alteromonas macleodii (strain DSM 17117 / Deep ecotype) [Complete proteome] [HAMAP]

Taxonomic identifier

314275 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Alteromonas

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	Phosphoglucosamine mutase HAMAP MF_01554		PRO_1000201056
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B4RXA8-1 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 55AF17CCDAEEEF98	FASTA	447	47,842
	10 20 30 40 50 60 MTQRKYFGTD GIRGKVGESN INPEFVTKLG WAAGKVLAGR GTNKVLIGKD TRISGYMLES 70 80 90 100 110 120 SLEAGLSAAG INIGLLGPMP TPAIAYLTKT FRSEAGIVIS ASHNPFYDNG IKFFSAQGFK 130 140 150 160 170 180 LDDDIELAIE AMLEQPMTCV ASDKLGKATR INDAAGRYIE FCKGTFPSEL SLTGLKIVVD 190 200 210 220 230 240 CAHGATYHIA PNVLRELGAT VIELGTTPDG LNINDGVGAT SMKAIVEKVK ESGADLGFAL 250 260 270 280 290 300 DGDGDRIMMV DHLGNVLDGD QIVYIIARDA LKNGKMQGGV VGTLMSNLGL ENALSKLGVP 310 320 330 340 350 360 FARSNVGDRY VMELLQQKGW SIGGENSGHV LNLNMSSTGD GIVAGLQVLA AMLRSHMDLH 370 380 390 400 410 420 DLASGFDMYP QTLVNVRYTN QDIDYLAHAD VQNAKQEAEL ALGKTGRVLL RKSGTEPLIR 430 440 VMVESNDEAQ SHKWAEHIAE TVRNLAN

References

[1]

"Comparative genomics of two ecotypes of the marine planktonic copiotroph Alteromonas macleodii suggests alternative lifestyles associated with different kinds of particulate organic matter." Ivars-Martinez E., Martin-Cuadrado A.-B., D'Auria G., Mira A., Ferriera S., Johnson J., Friedman R., Rodriguez-Valera F. ISME J. 2:1194-1212(2008) [PubMed: 18670397] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001103 Genomic DNA. Translation: ACG65992.1.
RefSeq	YP_002125986.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6775619.
GenomeReviews	Gene locus MADE_01688 in contig CP001103_GR.
KEGG	amc:MADE_01688.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	VHDRYIE.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_ALTMD

Accession

Primary (citable) accession number: B4RXA8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 23, 2008
Last modified:	November 3, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)