B4RX40 (TAL_ALTMD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	MADE_1015450

Organism

Alteromonas macleodii (strain DSM 17117 / Deep ecotype) [Complete proteome] [HAMAP]

Taxonomic identifier

314275 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Alteromonas › Alteromonas macleodii

Protein attributes

Sequence length	319 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP-Rule MF_00492
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP-Rule MF_00492
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP-Rule MF_00492
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pentose-phosphate shunt Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 319	319	Transaldolase HAMAP-Rule MF_00492		PRO_1000126235
Sites
	Active site	132	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	B4RX40 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: C7AEDCB3EEEBB19F	FASTA	319	34,705
	10 20 30 40 50 60 MSNQLASLRD ITTVVADTGD IDAIKKYQPV DATTNPSLLL KAAGLPQYAS LIDDAVAWAK 70 80 90 100 110 120 LQSNDAEQQL TDASDKLAVA IGKEISGTIP GRISTEVDAR LSFDTAATIE KAERLVQLYE 130 140 150 160 170 180 DAGIDKSRIL IKIASTWEGI QAAEALEKKG IQCNLTLLFS FAQAQACAEA GVYLISPFVG 190 200 210 220 230 240 RILDWYKKAT GTESYAPDED PGVVSVTKIY NYYKEHGYKT VVMGASFRNI GEIQALAGCD 250 260 270 280 290 300 RLTISPALLE ELANEPGDLE VKLKDNDATK TPGERLTESE FRWAMNEDAM ATEKLSEGIR 310 NFAADQEKLE ATLREKLSA

References

[1]

"Comparative genomics of two ecotypes of the marine planktonic copiotroph Alteromonas macleodii suggests alternative lifestyles associated with different kinds of particulate organic matter." Ivars-Martinez E., Martin-Cuadrado A.-B., D'Auria G., Mira A., Ferriera S., Johnson J., Friedman R., Rodriguez-Valera F. ISME J. 2:1194-1212(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 17117 / Deep ecotype.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001103 Genomic DNA. Translation: AEA99222.1.
RefSeq	YP_004428220.1. NC_011138.2.
3D structure databases
ProteinModelPortal	B4RX40.
SMR	B4RX40. Positions 2-317.
ModBase	Search...
Protein-protein interaction databases
STRING	314275.MADE_03321.
Proteomic databases
PRIDE	B4RX40.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEA99222; AEA99222; MADE_1015450.
GeneID	10558440.
KEGG	amc:MADE_1015450.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0176.
KO	K00616.
OMA	EYKPQDA.
ProtClustDB	PRK05269.
Enzyme and pathway databases
BioCyc	AMAC314275:GHA7-3123-MONOMER.
UniPathway	UPA00115; UER00414.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00492. Transaldolase_1.
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_1. IPR018225. Transaldolase_AS. [Graphical view]
PANTHER	PTHR10683. PTHR10683. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. talAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_ALTMD

Accession

Primary (citable) accession number: B4RX40
Secondary accession number(s): F2GD86

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program