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Protein

Transaldolase

Gene

tal

Organism
Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei132Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:MADE_1015450
OrganismiAlteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)
Taxonomic identifieri1774373 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeAlteromonas
Proteomesi
  • UP000001870 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001262351 – 319TransaldolaseAdd BLAST319

Proteomic databases

PRIDEiB4RX40

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliB4RX40
SMRiB4RX40
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CW3 Bacteria
COG0176 LUCA
KOiK00616
OMAiMAFDKLH

Family and domain databases

CDDicd00957 Transaldolase_TalAB, 1 hit
Gene3Di3.20.20.701 hit
HAMAPiMF_00492 Transaldolase_1, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001585 TAL/FSA
IPR004730 Transaldolase_1
IPR018225 Transaldolase_AS
PANTHERiPTHR10683 PTHR10683, 1 hit
PTHR10683:SF20 PTHR10683:SF20, 1 hit
PfamiView protein in Pfam
PF00923 TAL_FSA, 1 hit
TIGRFAMsiTIGR00874 talAB, 1 hit
PROSITEiView protein in PROSITE
PS01054 TRANSALDOLASE_1, 1 hit
PS00958 TRANSALDOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

B4RX40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNQLASLRD ITTVVADTGD IDAIKKYQPV DATTNPSLLL KAAGLPQYAS
60 70 80 90 100
LIDDAVAWAK LQSNDAEQQL TDASDKLAVA IGKEISGTIP GRISTEVDAR
110 120 130 140 150
LSFDTAATIE KAERLVQLYE DAGIDKSRIL IKIASTWEGI QAAEALEKKG
160 170 180 190 200
IQCNLTLLFS FAQAQACAEA GVYLISPFVG RILDWYKKAT GTESYAPDED
210 220 230 240 250
PGVVSVTKIY NYYKEHGYKT VVMGASFRNI GEIQALAGCD RLTISPALLE
260 270 280 290 300
ELANEPGDLE VKLKDNDATK TPGERLTESE FRWAMNEDAM ATEKLSEGIR
310
NFAADQEKLE ATLREKLSA
Length:319
Mass (Da):34,705
Last modified:September 23, 2008 - v1
Checksum:iC7AEDCB3EEEBB19F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001103 Genomic DNA Translation: AEA99222.1
RefSeqiWP_012519514.1, NC_011138.3

Genome annotation databases

EnsemblBacteriaiAEA99222; AEA99222; MADE_1015450
KEGGiamc:MADE_1015450

Similar proteinsi

Entry informationi

Entry nameiTAL_ALTMD
AccessioniPrimary (citable) accession number: B4RX40
Secondary accession number(s): F2GD86
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome