B4RR79 (B4RR79_NEIG2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Homoserine kinase HAMAP-Rule MF_00301
Short name=HK HAMAP-Rule MF_00301
Short name=HSK HAMAP-Rule MF_00301
EC=2.7.1.39 HAMAP-Rule MF_00301

Gene names

Name:	thrB HAMAP-Rule MF_00301
Ordered Locus Names:	NGK_2537 EMBL ACF31137.1

Organism

Neisseria gonorrhoeae (strain NCCP11945) [Complete proteome] [HAMAP] EMBL ACF31137.1

Taxonomic identifier

521006 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria › Neisseria gonorrhoeae

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP-Rule MF_00301 SAAS SAAS005280
Pathway	Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP-Rule MF_00301 SAAS SAAS005280
Sequence similarities	Belongs to the pseudomonas-type ThrB family. HAMAP-Rule MF_00301

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Threonine biosynthesis HAMAP-Rule MF_00301 SAAS SAAS005280
Ligand	ATP-binding HAMAP-Rule MF_00301 SAAS SAAS005280 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00301 SAAS SAAS005280 EMBL ACF31137.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	threonine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW homoserine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4RR79 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: C56B5FBF0DF4ECA3	FASTA	305	33,596
	10 20 30 40 50 60 MSVYTSVSDD EMRGFLSGYD LGEFVSLQGI AQGITNSNYF LTTTSGRYVL TVFEVLKQEE 70 80 90 100 110 120 LSFFLELNRH LSMKGVAVAA PVARKDGRLD SVLAGKPACL VACLKGSDTA LPTAEQCFHT 130 140 150 160 170 180 GAMLAKMHLA AADFPLEMEN PRYDAWWTEA CARLLPVLSQ DDAALLCSEI DALKDNLGNH 190 200 210 220 230 240 LPSGIIHADL FKDNVLLDGG QVSGFIDFYY ACRGNFMYDL AIAVNDWART ADNKLDEALK 250 260 270 280 290 300 KAFIGGYEGV RPLSAGEKAY FPTAQRAGCI RFWVSRLLDF HFPQAGEMTF IKDPNAFRNL LLSLD

References

[1]	"Complete genome sequence of Neisseria gonorrhoeae NCCP11945." Chung G.T., Yoo J.S., Oh H.B., Lee Y.S., Cha S.H., Kim S.J., Yoo C.K. J. Bacteriol. 190:6035-6036(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCCP11945 EMBL ACF31137.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001050 Genomic DNA. Translation: ACF31137.1.
RefSeq	YP_002003162.1. NC_011035.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	521006.NGK_2537.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACF31137; ACF31137; NGK_2537.
GeneID	6449613.
KEGG	ngk:NGK_2537.
PATRIC	20343854. VBINeiGon87511_2755.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2334.
HOGENOM	HOG000004810.
KO	K02204.
OMA	PDNVFFL.
ProtClustDB	PRK05231.
Enzyme and pathway databases
BioCyc	NGON521006:GJ73-2610-MONOMER.
UniPathway	UPA00050; UER00064.
Family and domain databases
HAMAP	MF_00301. Homoser_kinase_2.
InterPro	IPR002575. Aminoglycoside_PTrfase. IPR005280. Homoserine_kinase_ThrB. IPR011009. Kinase-like_dom. [Graphical view]
Pfam	PF01636. APH. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
TIGRFAMs	TIGR00938. thrB_alt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B4RR79_NEIG2

Accession

Primary (citable) accession number: B4RR79

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 1, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)