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B4RQL0

- B4RQL0_NEIG2

UniProt

B4RQL0 - B4RQL0_NEIG2

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Protein

Phosphoenolpyruvate carboxylase

Gene
ppc, NGK_2216
Organism
Neisseria gonorrhoeae (strain NCCP11945)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei163 – 1631 By similarityUniRule annotation
Active sitei591 – 5911 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotations

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciNGON521006:GJ73-2265-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:NGK_2216Imported
OrganismiNeisseria gonorrhoeae (strain NCCP11945)Imported
Taxonomic identifieri521006 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000002564: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi521006.NGK_2216.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiIDIVAQK.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4RQL0-1 [UniParc]FASTAAdd to Basket

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MNGLARMRHL RYIYSIYGNE RKIMQLHILN NPKDAALAAD AEFLKQSLFN    50
LLHEEASPLV VETVKLLSTS DDSAALIEKV LPQLDERQTY DLTLACGLFA 100
QILNIAEDVH HERRRQIHED AGHNAAEGSL TETVRRLKAG KADGKSVQRQ 150
LDNTSVTAVL TAHPTEVQRQ TVLNFNRRIR ALLPQRERCT NADALARLRR 200
EIDTVLLGLW QTSETRRHKL SVNDEINNGV SIFPMSFFEA LPKLYRKMEH 250
DFQTAYPDVR VPNILKIGGW IGGDRDGNPF VSGETLRFAF RRHADAVFRF 300
YRSELDKLYR ELPLSIRRVK VNDDVMALAA LSPDEEIART EEPYRRAIAY 350
IMARAMGKAR SLGLGMGCKF GFLEPYASAQ KFLDDLKKLQ RSLIDNGSRL 400
LAEGRLADLI RSVSVFGFHM MPLDLRQHAG KHADVVAELF QHAGLEDYNS 450
LNEEQKQAAL LRELGHQRPL YSPFITYSDH TRRELAIFNE ARKIKDEFGE 500
DAVTQSIISN CEQPGDLLAL ALLLKESGLL AVENGKPHSR INIVPLFETI 550
EALENACPVM ETMFRLDWYD ALLESRGNIQ EIMLGYSDSN KDGGYVTSSW 600
CLHQAELGLV ELFKKYDVRM RLFHGRGGSV GRGGGPSYQA ILAQPAGSVA 650
GQIRITEQGE VITAKYADPG NAQRNLETLV AATLEASILP DKKDPDAKLM 700
QALSDVSFKY YRELITHPDF IDYFLQTSPI QEIATLNLGS RPASRKTLAR 750
IQDLRAIPWV FSWMQNRLML PAWYGFGSAV ETLCEGSPET LAALRGHAQN 800
NPFFQAMLSN MEQVMAKTDI TLAENYAGLS ESPEKAKVIF GMIKEEYRRS 850
RKALLDLLQT EELLRDNRSL ARSLALRIPY LNALNGLQVA MLKRLRKEPD 900
NPHALLMVHL TINGVAQGLR NTG 923
Length:923
Mass (Da):103,959
Last modified:September 23, 2008 - v1
Checksum:iF74A3AE6907B96DB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001050 Genomic DNA. Translation: ACF30820.1.
RefSeqiYP_002002841.1. NC_011035.1.

Genome annotation databases

EnsemblBacteriaiACF30820; ACF30820; NGK_2216.
GeneIDi6447569.
KEGGingk:NGK_2216.
PATRICi20343097. VBINeiGon87511_2394.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001050 Genomic DNA. Translation: ACF30820.1 .
RefSeqi YP_002002841.1. NC_011035.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 521006.NGK_2216.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACF30820 ; ACF30820 ; NGK_2216 .
GeneIDi 6447569.
KEGGi ngk:NGK_2216.
PATRICi 20343097. VBINeiGon87511_2394.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238647.
KOi K01595.
OMAi IDIVAQK.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci NGON521006:GJ73-2265-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Neisseria gonorrhoeae NCCP11945."
    Chung G.T., Yoo J.S., Oh H.B., Lee Y.S., Cha S.H., Kim S.J., Yoo C.K.
    J. Bacteriol. 190:6035-6036(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCCP11945Imported.

Entry informationi

Entry nameiB4RQL0_NEIG2
AccessioniPrimary (citable) accession number: B4RQL0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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