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B4RN04 (B4RN04_NEIG2) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP MF_01201 RuleBase RU000608
EC=5.1.1.1 HAMAP MF_01201 RuleBase RU000608
Gene names
Name:alr HAMAP MF_01201
Ordered Locus Names:NGK_1514
OrganismNeisseria gonorrhoeae (strain NCCP11945) [Complete proteome] [HAMAP]
Taxonomic identifier521006 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 SAAS SAAS009006

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site331Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2501Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue331N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
B4RN04 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 5965E6C3E931359D

FASTA35238,847
        10         20         30         40         50         60 
MRPLNVQIRL GNLRHNYRIL KEMHGGKLLA VVKADAYGHG AVRCAFALAD LADGFAVATI 

        70         80         90        100        110        120 
DEGIRLRESG ITHPIVLLEG VFEASEYEAV EQYSLWPAVG NQWQLEALLS RHWKKPVKVW 

       130        140        150        160        170        180 
LKMDSGMHRT GFFPHDYASA YAALKQSEYV DSIVKFSHFS CADEPESGMT EIQMEAFDLG 

       190        200        210        220        230        240 
TKGLEGEESL ANSAAILNIP EARRDWGRAG LALYGISPFG GSDDRLKPVM RLSTRIFGER 

       250        260        270        280        290        300 
VLQPHSPIGY GATFYTSKST RVGLIACGYA DGYPRRAPSN SPVAVDGKLT RVIGRISMDM 

       310        320        330        340        350 
MTIELDASQE GLGHEVELWG DTVNINTVAE AAGTIPYELM CNIKRAKFTY IE

« Hide

References

[1]"Complete genome sequence of Neisseria gonorrhoeae NCCP11945."
Chung G.T., Yoo J.S., Oh H.B., Lee Y.S., Cha S.H., Kim S.J., Yoo C.K.
J. Bacteriol. 190:6035-6036(2008) [PubMed: 18586945] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001050 Genomic DNA. Translation: ACF30172.1.
RefSeqYP_002002139.1. NC_011035.1.

3D structure databases

ProteinModelPortalB4RN04.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4RN04.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBNEIT00000004636; EBNEIP00000004408; EBNEIG00000004636.
GeneID6447878.
GenomeReviewsGene locus NGK_1514 in contig CP001050_GR.
KEGGngk:NGK_1514.
PATRIC20341489. VBINeiGon87511_1610.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000021248.
HOGENOMHBG712172.
OMAEGTPVWV.
ProtClustDBCLSK878163.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4RN04_NEIG2
AccessionPrimary (citable) accession number: B4RN04
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info