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B4RM12 (GLK_NEIG2) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucokinase

EC=2.7.1.2
Alternative name(s):
Glucose kinase
Gene names
Name:glk
Ordered Locus Names:NGK_1172
OrganismNeisseria gonorrhoeae (strain NCCP11945) [Complete proteome] [HAMAP]
Taxonomic identifier521006 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Protein attributes

Sequence length328 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00524.

Sequence similarities

Belongs to the bacterial glucokinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glucokinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 328328Glucokinase HAMAP-Rule MF_00524
PRO_1000127712

Regions

Nucleotide binding16 – 216ATP Potential

Sequences

Sequence LengthMass (Da)Tools
B4RM12 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 865E894DDE3E6FF4

FASTA32835,084
        10         20         30         40         50         60 
MSSTPNKHAD YPRLVADIGG TNARFALETA PCVIEKVAVL PCKEYDTVTD AVRAYLNQSG 

        70         80         90        100        110        120 
ATGVRHAAFA IANPILGDWV QMTNHHWAFS IETTRQALGL DTLILLNDFT AQALAVTQTS 

       130        140        150        160        170        180 
SKDLMQVGGQ KPVEFAPKAV IGPGTGLGVS GLVHSPAGWV ALAGEGGHTS FPPFDDMEVL 

       190        200        210        220        230        240 
IWQYAKNKYR HVSAERFLSG AGLSLIYETL AAKQKAEPAK LMPSEITEKA LNCESPLCRQ 

       250        260        270        280        290        300 
ALDIFCAMLG TVASNLALTL GARGGVYLCG GIIPRMLDYF KTSPFRSRFE NKGRFEAYLA 

       310        320 
AIPVYVVLSE FPGIAGAAAA LGNHLKNV 

« Hide

References

[1]"Complete genome sequence of Neisseria gonorrhoeae NCCP11945."
Chung G.T., Yoo J.S., Oh H.B., Lee Y.S., Cha S.H., Kim S.J., Yoo C.K.
J. Bacteriol. 190:6035-6036(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCCP11945.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001050 Genomic DNA. Translation: ACF29849.1.
RefSeqYP_002001797.1. NC_011035.1.

3D structure databases

ProteinModelPortalB4RM12.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING521006.NGK_1172.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACF29849; ACF29849; NGK_1172.
GeneID6447798.
KEGGngk:NGK_1172.
PATRIC20340782. VBINeiGon87511_1256.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0837.
HOGENOMHOG000274469.
KOK00845.
OMADWVEMTN.
OrthoDBEOG64BQ47.
ProtClustDBPRK00292.

Enzyme and pathway databases

BioCycNGON521006:GJ73-1196-MONOMER.

Family and domain databases

HAMAPMF_00524. Glucokinase.
InterProIPR003836. Glucokinase.
[Graphical view]
PfamPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00749. glk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLK_NEIG2
AccessionPrimary (citable) accession number: B4RM12
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families