Reviewed, UniProtKB/Swiss-Prot B4RLK3 (GLND_NEIG2)

Names and origin

Protein names

Recommended name:
    [Protein-PII] uridylyltransferase
      Short name=PII uridylyl-transferase
    EC=2.7.7.59
Alternative name(s):
    Uridylyl-removing enzyme
    UTase

Gene names

Name:	glnD
Ordered Locus Names:	NGK_1013

Organism

Neisseria gonorrhoeae (strain NCCP11945) [Complete proteome] [HAMAP]

Taxonomic identifier

521006 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	852 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity.
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 852	852	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_1000114756

Sequences

	Sequence		Length	Mass (Da)
	B4RLK3-1 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 4B3EC476F18EA2DE	FASTA	852	96,996
	10 20 30 40 50 60 MPENLSSALE TFKQQRNAAE AHYLKANRVS VFFREYTAAV ETLLAALWAE HFQNSALCLM 70 80 90 100 110 120 AVGGFGRGEP YPCSDVDLAV VSPAPLSDGI QEQIARFIQT LWDCKLMPSV KSGSVDELCE 130 140 150 160 170 180 SVRDDITGDT AFLEARFLFG NRQTADELAE KMNVQRNVAA FIEAKLVEME HRHAKSQGSG 190 200 210 220 230 240 AVLEPNIKSC PGGLRDIHTL LWIAKAQGLA ANLPDLLKQR ILTRAEAGML SHGYRRLAHI 250 260 270 280 290 300 RIRLHLNAKR AEDRLLFDLQ PQVAESMGYQ DENRRRQSEE LMRVFYRAVK TVKQLGGILT 310 320 330 340 350 360 PMLRSRVSST PMRVTLRIDD DYIQVNNQIA ARHTDIFFRR PEHIFKIVEI MQQRNDITAL 370 380 390 400 410 420 EPQTLRAWWG ATRKINRSFY QNSENRRRFA GFFRSGNGLT QTLRFLNLYG VLGRYLPAWE 430 440 450 460 470 480 KIVGLLQHDL FHIYPVDDHI LAVVRNVRRL ALDMHSHELP YASALMQSFE KQDILYLAAF 490 500 510 520 530 540 FHDIAKGRGG DHAVQGIADA RQFAADHFLT EEESDLLAWL VENHLLMSAV AQKEDIQDPG 550 560 570 580 590 600 VLDAFCKRVQ THERLSALYL LTISDIRGTN PKLWNAWRAS LLESLFHAAG RCLAGNDGNP 610 620 630 640 650 660 HALFGRRRQE AADLLTRAAV PEKQQKKLWN ALGSAYFARH QSREILWHAA NLVHDFEPPI 670 680 690 700 710 720 VRSRILPQSD SFQVMVFMPN GPRLFARLCR IFSRHGFDIL AARAFITEHD YILDTFIVQI 730 740 750 760 770 780 PSQHAPEDYP DIQSALEAEL NSFIHGHTVA ETQSCNRRIS RRSRYMPIAP SITITPEEDY 790 800 810 820 830 840 PDRYSVEITA VNRPFLLADM AEVFFAHNVS LRYAKISTLD ERVEDSFTVF SPDLKNPKIQ 850 SSLKQALLEQ LA

References

[1]	"Complete genome sequence of Neisseria gonorrhoeae NCCP11945." Chung G.T., Yoo J.S., Oh H.B., Lee Y.S., Cha S.H., Kim S.J., Yoo C.K. J. Bacteriol. 190:6035-6036(2008) [PubMed: 18586945] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001050 Genomic DNA. Translation: ACF29690.1.
RefSeq	YP_002001638.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6447692.
GenomeReviews	Gene locus NGK_1013 in contig CP001050_GR.
KEGG	ngk:NGK_1013.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	MQHDLFH.
Family and domain databases
HAMAP	MF_00277. [Tree]
InterPro	IPR002912. ACT_bd. IPR005105. DUF294_Ntrans. IPR010043. GlnD_Uridyltrans. IPR003607. Met-dep_phosphohydro_HD. IPR006674. Met-dep_phosphohydro_HD_sub. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF03445. DUF294. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_NEIG2

Accession

Primary (citable) accession number: B4RLK3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	September 23, 2008
Last modified:	November 3, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)