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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Neisseria gonorrhoeae (strain NCCP11945)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:NGK_0832
OrganismiNeisseria gonorrhoeae (strain NCCP11945)
Taxonomic identifieri521006 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000002564 Componenti: Chromosome

Subcellular locationi

B4RL22:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953841 – 572Arginine--tRNA ligaseAdd BLAST572

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB4RL22.
SMRiB4RL22.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247212.
KOiK01887.
OMAiNKPLHLG.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

B4RL22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLHQTVEHE AAAAFAAAGI AGSPVVLQPT KNAEHGDFQI NGVMGAAKKA
60 70 80 90 100
KQNPRELAQK VADALAGNAV IESAEVAGPG FINLRLRHEF LAQNIHAALN
110 120 130 140 150
DARFGVAKTA QPQTVVIDYS SPNLAKEMHV GHLRSSIIGD SISRVLEFTG
160 170 180 190 200
NTVIRQNHVG DWGTQFGMLV AYLVEQQKDN AAFELADLEQ FYRAAKVRFD
210 220 230 240 250
EDPAFADTAR EYVVKLQGGD ETVLALWKQF VDISLSHAQA VYDTLGLKLR
260 270 280 290 300
PEDVAGESKY NDDLQPVADD LVQKGLAVED DGAKVVFLDE FKNKEGEPAA
310 320 330 340 350
FIVQKQGGGF LYASTDLACL RYRIGRLKAG RLLYVVDHRQ ALHFEQLFTT
360 370 380 390 400
SRKAGYLPEN AKAEFIGFGT MMGKDGKPFK TRSGDTVKLV DLLTEAVERA
410 420 430 440 450
TALVKEKNPE LGADEAAKIG KTVGIGAVKY ADLSKNRTSD YVFDWDAMLS
460 470 480 490 500
FEGNTAPYLQ YAYTRVQSVF RKAGEWDATA PTVLTEPLEK QLAAELLKFE
510 520 530 540 550
NVLQSVADTA YPHYLAAYLY QAATLFSRFY EACPILKAEG ASRNSRLQLA
560 570
KLTGNTLKQG LDLLGIDVLD VM
Length:572
Mass (Da):62,619
Last modified:September 23, 2008 - v1
Checksum:iE63B0879504F9020
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001050 Genomic DNA. Translation: ACF29513.1.
RefSeqiWP_003688336.1. NC_011035.1.

Genome annotation databases

EnsemblBacteriaiACF29513; ACF29513; NGK_0832.
KEGGingk:NGK_0832.

Similar proteinsi

Entry informationi

Entry nameiSYR_NEIG2
AccessioniPrimary (citable) accession number: B4RL22
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: October 25, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families