Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Arginine--tRNA ligase

Gene

argS

Organism
Neisseria gonorrhoeae (strain NCCP11945)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:NGK_0832
OrganismiNeisseria gonorrhoeae (strain NCCP11945)
Taxonomic identifieri521006 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000002564 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953841 – 572Arginine--tRNA ligaseAdd BLAST572

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

Secondary structure

1572
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 17Combined sources15
Beta strandi27 – 29Combined sources3
Beta strandi37 – 40Combined sources4
Helixi43 – 47Combined sources5
Turni48 – 51Combined sources4
Helixi54 – 64Combined sources11
Turni65 – 67Combined sources3
Beta strandi69 – 77Combined sources9
Turni78 – 80Combined sources3
Beta strandi81 – 86Combined sources6
Helixi88 – 100Combined sources13
Beta strandi114 – 118Combined sources5
Helixi130 – 148Combined sources19
Beta strandi152 – 157Combined sources6
Helixi165 – 179Combined sources15
Helixi188 – 201Combined sources14
Helixi203 – 218Combined sources16
Helixi221 – 245Combined sources25
Helixi251 – 253Combined sources3
Helixi257 – 263Combined sources7
Helixi264 – 273Combined sources10
Beta strandi276 – 280Combined sources5
Beta strandi283 – 288Combined sources6
Helixi289 – 291Combined sources3
Beta strandi299 – 304Combined sources6
Helixi312 – 325Combined sources14
Beta strandi330 – 337Combined sources8
Helixi338 – 340Combined sources3
Helixi341 – 353Combined sources13
Beta strandi362 – 368Combined sources7
Beta strandi376 – 378Combined sources3
Helixi389 – 407Combined sources19
Helixi413 – 433Combined sources21
Helixi445 – 448Combined sources4
Beta strandi451 – 455Combined sources5
Helixi456 – 473Combined sources18
Helixi487 – 496Combined sources10
Helixi499 – 509Combined sources11
Helixi513 – 532Combined sources20
Helixi540 – 563Combined sources24

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6AO8X-ray1.70A1-572[»]
ProteinModelPortaliB4RL22
SMRiB4RL22
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B4RL22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLHQTVEHE AAAAFAAAGI AGSPVVLQPT KNAEHGDFQI NGVMGAAKKA
60 70 80 90 100
KQNPRELAQK VADALAGNAV IESAEVAGPG FINLRLRHEF LAQNIHAALN
110 120 130 140 150
DARFGVAKTA QPQTVVIDYS SPNLAKEMHV GHLRSSIIGD SISRVLEFTG
160 170 180 190 200
NTVIRQNHVG DWGTQFGMLV AYLVEQQKDN AAFELADLEQ FYRAAKVRFD
210 220 230 240 250
EDPAFADTAR EYVVKLQGGD ETVLALWKQF VDISLSHAQA VYDTLGLKLR
260 270 280 290 300
PEDVAGESKY NDDLQPVADD LVQKGLAVED DGAKVVFLDE FKNKEGEPAA
310 320 330 340 350
FIVQKQGGGF LYASTDLACL RYRIGRLKAG RLLYVVDHRQ ALHFEQLFTT
360 370 380 390 400
SRKAGYLPEN AKAEFIGFGT MMGKDGKPFK TRSGDTVKLV DLLTEAVERA
410 420 430 440 450
TALVKEKNPE LGADEAAKIG KTVGIGAVKY ADLSKNRTSD YVFDWDAMLS
460 470 480 490 500
FEGNTAPYLQ YAYTRVQSVF RKAGEWDATA PTVLTEPLEK QLAAELLKFE
510 520 530 540 550
NVLQSVADTA YPHYLAAYLY QAATLFSRFY EACPILKAEG ASRNSRLQLA
560 570
KLTGNTLKQG LDLLGIDVLD VM
Length:572
Mass (Da):62,619
Last modified:September 23, 2008 - v1
Checksum:iE63B0879504F9020
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001050 Genomic DNA Translation: ACF29513.1
RefSeqiWP_003688336.1, NC_011035.1

Genome annotation databases

EnsemblBacteriaiACF29513; ACF29513; NGK_0832
KEGGingk:NGK_0832

Similar proteinsi

Entry informationi

Entry nameiSYR_NEIG2
AccessioniPrimary (citable) accession number: B4RL22
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: March 28, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health