B4RIX8 (B4RIX8_NEIG2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosyl-ATP pyrophosphatase HAMAP MF_01020
Short name=PRA-PH HAMAP MF_01020
EC=3.6.1.31 HAMAP MF_01020

Gene names

Name:	hisE HAMAP MF_01020
Ordered Locus Names:	NGK_0239

Organism

Neisseria gonorrhoeae (strain NCCP11945) [Complete proteome] [HAMAP]

Taxonomic identifier

521006 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	150 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(5-phosphoribosyl)-ATP + H2O = 1-(5-phosphoribosyl)-AMP + diphosphate. HAMAP MF_01020 SAAS SAAS008179
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9. HAMAP MF_01020 SAAS SAAS008179
Subcellular location	Cytoplasm By similarity HAMAP MF_01020.
Sequence similarities	Belongs to the PRA-PH family. HAMAP MF_01020

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01020 SAAS SAAS008179
Cellular component	Cytoplasm HAMAP MF_01020
Ligand	ATP-binding HAMAP MF_01020 SAAS SAAS008179 Nucleotide-binding
Molecular function	Hydrolase HAMAP MF_01020 SAAS SAAS008179 EMBL ACF28935.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosyl-ATP diphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4RIX8 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 1F832DE41ECF4A48	FASTA	150	16,979
	10 20 30 40 50 60 MQQHKCRLKR SDGIFQRNAT GVLPESSRLA YHSEQTETNR RKIMGDSVLS AIQQTIIQRK 70 80 90 100 110 120 SADPSESYVA QLLHKGEDKI LKKVIEEAGE VLMASKDKDP SHLVYEVADL WFHTMILLTH 130 140 150 HDLKAEDVLD ELSRRQGLSG LAEKAARTES

References

[1]	"Complete genome sequence of Neisseria gonorrhoeae NCCP11945." Chung G.T., Yoo J.S., Oh H.B., Lee Y.S., Cha S.H., Kim S.J., Yoo C.K. J. Bacteriol. 190:6035-6036(2008) [PubMed: 18586945] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001050 Genomic DNA. Translation: ACF28935.1.
RefSeq	YP_002000864.1. NC_011035.1.
3D structure databases
ProteinModelPortal	B4RIX8.
ModBase	Search...
Protein-protein interaction databases
STRING	B4RIX8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBNEIT00000004997; EBNEIP00000004769; EBNEIG00000004997.
GeneID	6447912.
GenomeReviews	Gene locus NGK_0239 in contig CP001050_GR.
KEGG	ngk:NGK_0239.
PATRIC	20338760. VBINeiGon87511_0263.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000021343.
HOGENOM	HBG646527.
OMA	SNIVHEA.
ProtClustDB	PRK00400.
Family and domain databases
HAMAP	MF_01020. HisE. [Tree]
InterPro	IPR008179. PRib-ATP_PPHydrolase. IPR021130. PRib-ATP_PPHydrolase-like. [Graphical view]
KO	K01523.
Pfam	PF01503. PRA-PH. 1 hit. [Graphical view]
TIGRFAMs	TIGR03188. Histidine_hisI. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B4RIX8_NEIG2

Accession

Primary (citable) accession number: B4RIX8

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)