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Protein

Uronate isomerase

Gene

uxaC

Organism
Phenylobacterium zucineum (strain HLK1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciPZUC450851:GHUG-2487-MONOMER.
RETL1328306-WGS:GSTH-93-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:PHZ_c2452
OrganismiPhenylobacterium zucineum (strain HLK1)
Taxonomic identifieri450851 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaePhenylobacterium
Proteomesi
  • UP000001868 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 480480Uronate isomerasePRO_1000131599Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi450851.PHZ_c2452.

Structurei

3D structure databases

ProteinModelPortaliB4RGF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000238114.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

B4RGF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRPLRLHPD RLFPADAGTR DIARRLYGSV KDLPIISPHG HTDPEWFAGD
60 70 80 90 100
APFPDATNLF LAPDHYLYRM LYSQGVPLDR LGVPSKAGPS PADPREAWRM
110 120 130 140 150
LASNMHLFRG TPSSMWLNHV FGEVFGFEIE LSAETADLYF DRIGEALQSP
160 170 180 190 200
AFRPRALFER FNIELLATTE SPTDDLRHHK AMRASGWKGR VVTAYRPDPV
210 220 230 240 250
IDAEHEDFRA SLSRFGELTG QDVESWSGYL QAHRMRRAAF MEMGATSTDH
260 270 280 290 300
GHPTAATADL SLADAEALFR KLLSADFSPA DAELFRAQML TEMARMSLDD
310 320 330 340 350
GLVMQIHPGS FRNHNAGLFA RYGRDKGADI PTRTDYVRAL KPLLDRFGNE
360 370 380 390 400
RGLSVIVFTL DESSYARELA PLAGHYPVLK LGPAWWFHDS PEGMRRFREQ
410 420 430 440 450
TTETAGFYNT VGFNDDTRAF LSIPARHDVA RRIDAGFLAR LVAEHRLSED
460 470 480
DAHETAVDLA YNLPKRAYKL DEPARTPAAA
Length:480
Mass (Da):53,883
Last modified:September 23, 2008 - v1
Checksum:i9DD7A35D0A5DD028
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000747 Genomic DNA. Translation: ACG78861.1.
RefSeqiWP_012522999.1. NC_011144.1.

Genome annotation databases

EnsemblBacteriaiACG78861; ACG78861; PHZ_c2452.
KEGGipzu:PHZ_c2452.
PATRICi22928040. VBIPheZuc44517_3084.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000747 Genomic DNA. Translation: ACG78861.1.
RefSeqiWP_012522999.1. NC_011144.1.

3D structure databases

ProteinModelPortaliB4RGF5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi450851.PHZ_c2452.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACG78861; ACG78861; PHZ_c2452.
KEGGipzu:PHZ_c2452.
PATRICi22928040. VBIPheZuc44517_3084.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000238114.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciPZUC450851:GHUG-2487-MONOMER.
RETL1328306-WGS:GSTH-93-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_PHEZH
AccessioniPrimary (citable) accession number: B4RGF5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: September 7, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.