Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peptide chain release factor 2

Gene

prfB

Organism
Phenylobacterium zucineum (strain HLK1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide chain release factor 2UniRule annotation
Short name:
RF-2UniRule annotation
Gene namesi
Name:prfBUniRule annotation
Ordered Locus Names:PHZ_c1839
OrganismiPhenylobacterium zucineum (strain HLK1)
Taxonomic identifieri450851 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaePhenylobacterium
Proteomesi
  • UP000001868 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000935501 – 369Peptide chain release factor 2Add BLAST369

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei247N5-methylglutamineUniRule annotation1

Post-translational modificationi

Methylated by PrmC. Methylation increases the termination efficiency of RF2.UniRule annotation

Keywords - PTMi

Methylation

Interactioni

Protein-protein interaction databases

STRINGi450851.PHZ_c1839

Structurei

3D structure databases

ProteinModelPortaliB4RCR3
SMRiB4RCR3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prokaryotic/mitochondrial release factor family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CG1 Bacteria
COG1186 LUCA
HOGENOMiHOG000074814
KOiK02836
OMAiYVFHPYQ
OrthoDBiPOG091H027X

Family and domain databases

HAMAPiMF_00094 Rel_fac_2, 1 hit
InterProiView protein in InterPro
IPR005139 PCRF
IPR000352 Pep_chain_release_fac_I_II
IPR004374 PrfB
PfamiView protein in Pfam
PF03462 PCRF, 1 hit
PF00472 RF-1, 1 hit
SMARTiView protein in SMART
SM00937 PCRF, 1 hit
TIGRFAMsiTIGR00020 prfB, 1 hit
PROSITEiView protein in PROSITE
PS00745 RF_PROK_I, 1 hit

Sequencei

Sequence statusi: Complete.

B4RCR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRPPRPTSS SRSNCSGGVF DWEPALRKLD ELNARVEDPT LWNDPDEAQA
60 70 80 90 100
VSRERSRLSA QVEAVHGLER DLADALGYAE LADEEGDEAS LDEARAQLRE
110 120 130 140 150
IKERAARAEL EALLSGEADG NDAYVEINSG AGGTESNDWA GMLLRMYTRW
160 170 180 190 200
AQAHGMSVDV IEETAGEQAG IKSVTLQVKG TNAYGWLKTE AGVHRLVRIS
210 220 230 240 250
PYDSSARRHT SFASVWVYPV IDDNIEIEIN PADVRTDTYR ASGAGGQHVN
260 270 280 290 300
KTDSAVRLTH IPTGIAVACQ TQRSQHQNRD QAWKMLRARL YELELEKREA
310 320 330 340 350
AQQALEDQKT DIGWGHQIRS YVLQPYQMVK DLRTEVETSD TQGVLDGDLD
360
AFMGAALAQR VGATRDAAA
Length:369
Mass (Da):40,678
Last modified:September 23, 2008 - v1
Checksum:i72FFBEC4090E22EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000747 Genomic DNA Translation: ACG78250.1
RefSeqiWP_012522392.1, NC_011144.1

Genome annotation databases

EnsemblBacteriaiACG78250; ACG78250; PHZ_c1839
KEGGipzu:PHZ_c1839

Similar proteinsi

Entry informationi

Entry nameiRF2_PHEZH
AccessioniPrimary (citable) accession number: B4RCR3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: December 20, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome