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Protein

Peptide chain release factor 2

Gene

prfB

Organism
Phenylobacterium zucineum (strain HLK1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide chain release factor 2UniRule annotation
Short name:
RF-2UniRule annotation
Gene namesi
Name:prfBUniRule annotation
Ordered Locus Names:PHZ_c1839
OrganismiPhenylobacterium zucineum (strain HLK1)
Taxonomic identifieri450851 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaePhenylobacterium
Proteomesi
  • UP000001868 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000935501 – 369Peptide chain release factor 2Add BLAST369

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei247N5-methylglutamineUniRule annotation1

Post-translational modificationi

Methylated by PrmC. Methylation increases the termination efficiency of RF2.UniRule annotation

Keywords - PTMi

Methylation

Interactioni

Protein-protein interaction databases

STRINGi450851.PHZ_c1839.

Structurei

3D structure databases

ProteinModelPortaliB4RCR3.
SMRiB4RCR3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prokaryotic/mitochondrial release factor family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CG1. Bacteria.
COG1186. LUCA.
HOGENOMiHOG000074814.
KOiK02836.
OMAiYVFHPYQ.
OrthoDBiPOG091H027X.

Family and domain databases

HAMAPiMF_00094. Rel_fac_2. 1 hit.
InterProiView protein in InterPro
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004374. PrfB.
IPR020853. RF2_bac.
PfamiView protein in Pfam
PF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
SMARTiView protein in SMART
SM00937. PCRF. 1 hit.
TIGRFAMsiTIGR00020. prfB. 1 hit.
PROSITEiView protein in PROSITE
PS00745. RF_PROK_I. 1 hit.

Sequencei

Sequence statusi: Complete.

B4RCR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRPPRPTSS SRSNCSGGVF DWEPALRKLD ELNARVEDPT LWNDPDEAQA
60 70 80 90 100
VSRERSRLSA QVEAVHGLER DLADALGYAE LADEEGDEAS LDEARAQLRE
110 120 130 140 150
IKERAARAEL EALLSGEADG NDAYVEINSG AGGTESNDWA GMLLRMYTRW
160 170 180 190 200
AQAHGMSVDV IEETAGEQAG IKSVTLQVKG TNAYGWLKTE AGVHRLVRIS
210 220 230 240 250
PYDSSARRHT SFASVWVYPV IDDNIEIEIN PADVRTDTYR ASGAGGQHVN
260 270 280 290 300
KTDSAVRLTH IPTGIAVACQ TQRSQHQNRD QAWKMLRARL YELELEKREA
310 320 330 340 350
AQQALEDQKT DIGWGHQIRS YVLQPYQMVK DLRTEVETSD TQGVLDGDLD
360
AFMGAALAQR VGATRDAAA
Length:369
Mass (Da):40,678
Last modified:September 23, 2008 - v1
Checksum:i72FFBEC4090E22EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000747 Genomic DNA. Translation: ACG78250.1.
RefSeqiWP_012522392.1. NC_011144.1.

Genome annotation databases

EnsemblBacteriaiACG78250; ACG78250; PHZ_c1839.
KEGGipzu:PHZ_c1839.

Similar proteinsi

Entry informationi

Entry nameiRF2_PHEZH
AccessioniPrimary (citable) accession number: B4RCR3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: August 30, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families