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Protein

Peptide chain release factor 2

Gene

prfB

Organism
Phenylobacterium zucineum (strain HLK1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciPZUC450851:GHUG-1868-MONOMER.
RETL1328306-WGS:GSTH-1673-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide chain release factor 2UniRule annotation
Short name:
RF-2UniRule annotation
Gene namesi
Name:prfBUniRule annotation
Ordered Locus Names:PHZ_c1839
OrganismiPhenylobacterium zucineum (strain HLK1)
Taxonomic identifieri450851 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaePhenylobacterium
Proteomesi
  • UP000001868 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 369369Peptide chain release factor 2PRO_1000093550Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei247 – 2471N5-methylglutamineUniRule annotation

Post-translational modificationi

Methylated by PrmC. Methylation increases the termination efficiency of RF2.UniRule annotation

Keywords - PTMi

Methylation

Interactioni

Protein-protein interaction databases

STRINGi450851.PHZ_c1839.

Structurei

3D structure databases

ProteinModelPortaliB4RCR3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prokaryotic/mitochondrial release factor family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CG1. Bacteria.
COG1186. LUCA.
HOGENOMiHOG000074814.
KOiK02836.
OMAiRLYEHEM.
OrthoDBiPOG091H027X.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
HAMAPiMF_00094. Rel_fac_2. 1 hit.
InterProiIPR014720. dsRBD_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR020853. Peptide_chain_release_fac2_bac.
IPR004374. PrfB.
[Graphical view]
PANTHERiPTHR11075:SF6. PTHR11075:SF6. 1 hit.
PfamiPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTiSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00020. prfB. 1 hit.
PROSITEiPS00745. RF_PROK_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4RCR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRPPRPTSS SRSNCSGGVF DWEPALRKLD ELNARVEDPT LWNDPDEAQA
60 70 80 90 100
VSRERSRLSA QVEAVHGLER DLADALGYAE LADEEGDEAS LDEARAQLRE
110 120 130 140 150
IKERAARAEL EALLSGEADG NDAYVEINSG AGGTESNDWA GMLLRMYTRW
160 170 180 190 200
AQAHGMSVDV IEETAGEQAG IKSVTLQVKG TNAYGWLKTE AGVHRLVRIS
210 220 230 240 250
PYDSSARRHT SFASVWVYPV IDDNIEIEIN PADVRTDTYR ASGAGGQHVN
260 270 280 290 300
KTDSAVRLTH IPTGIAVACQ TQRSQHQNRD QAWKMLRARL YELELEKREA
310 320 330 340 350
AQQALEDQKT DIGWGHQIRS YVLQPYQMVK DLRTEVETSD TQGVLDGDLD
360
AFMGAALAQR VGATRDAAA
Length:369
Mass (Da):40,678
Last modified:September 23, 2008 - v1
Checksum:i72FFBEC4090E22EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000747 Genomic DNA. Translation: ACG78250.1.
RefSeqiWP_012522392.1. NC_011144.1.

Genome annotation databases

EnsemblBacteriaiACG78250; ACG78250; PHZ_c1839.
KEGGipzu:PHZ_c1839.
PATRICi22926638. VBIPheZuc44517_2389.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000747 Genomic DNA. Translation: ACG78250.1.
RefSeqiWP_012522392.1. NC_011144.1.

3D structure databases

ProteinModelPortaliB4RCR3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi450851.PHZ_c1839.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACG78250; ACG78250; PHZ_c1839.
KEGGipzu:PHZ_c1839.
PATRICi22926638. VBIPheZuc44517_2389.

Phylogenomic databases

eggNOGiENOG4105CG1. Bacteria.
COG1186. LUCA.
HOGENOMiHOG000074814.
KOiK02836.
OMAiRLYEHEM.
OrthoDBiPOG091H027X.

Enzyme and pathway databases

BioCyciPZUC450851:GHUG-1868-MONOMER.
RETL1328306-WGS:GSTH-1673-MONOMER.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
HAMAPiMF_00094. Rel_fac_2. 1 hit.
InterProiIPR014720. dsRBD_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR020853. Peptide_chain_release_fac2_bac.
IPR004374. PrfB.
[Graphical view]
PANTHERiPTHR11075:SF6. PTHR11075:SF6. 1 hit.
PfamiPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTiSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00020. prfB. 1 hit.
PROSITEiPS00745. RF_PROK_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRF2_PHEZH
AccessioniPrimary (citable) accession number: B4RCR3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: September 7, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.