B4RC79 (GLND_PHEZH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	PHZ_c3463

Organism

Phenylobacterium zucineum (strain HLK1) [Complete proteome] [HAMAP]

Taxonomic identifier

450851 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Phenylobacterium › Phenylobacterium zucineum

Protein attributes

Sequence length	938 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: EC amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 938	938	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_1000114757

Sequences

	Sequence		Length	Mass (Da)
	B4RC79 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 4D684D54FEEEB95E	FASTA	938	102,982
	10 20 30 40 50 60 MPPRLRPTHL EYVVDGVKLR SQLSAAALEH AGDELAQRRA ALEILKNALF RGRMIAKERL 70 80 90 100 110 120 ENGAGGIETA RLLSGVTDEV VSALYDFTTV HVFRARNPTE GERLALMAVG GYGRGTLAPF 130 140 150 160 170 180 SDIDLLFVRP YKQTAHAESV IEYMLYALWD LGFKVGHASR TIDECLKLSR EDFTIRTSIL 190 200 210 220 230 240 EARRLTGDEK LAGELVERFR KEVVKGTGAE FVAAKLKERD ERHARAGASR YMVEPNVKEG 250 260 270 280 290 300 KGGLRDLNTL FWIAQYLHPG ESLEKVMHLE IFDRREVRTF IQALDFLWAV RCHLHFATGR 310 320 330 340 350 360 PEERLSFDLQ PEIARRMGYG DRGDAPAVER FMRRYFLFAK DVGSLTRVFA AKLEADRVKT 370 380 390 400 410 420 APKGISRFIP GRAQKRKPLD EPGFHEVGGR LGVDPEIFEA DPVNLLKLFR IADQRNLDLH 430 440 450 460 470 480 PDAFTAASRA SGLITSAVRR DRHAAKVFLD ILARGRDPQR TLALMNEAGV LGRFVPEFGR 490 500 510 520 530 540 IVAQMQFNMY HSYTVDEHTL RAVGVIADIA AGRLAEDHPL AVQTMPLIAD REALFLAMLL 550 560 570 580 590 600 HDTGKGGAGG QELAGARAAR QACERLGLER SKIELVAWLV EHHLVMSDYA QKRDVSDPRT 610 620 630 640 650 660 VADFARIVQS PERLRLLLVL TVADIRAVGP GVWNGWKGQL MRELYTATEA VFRGGRGSDA 670 680 690 700 710 720 AAALKRYQEN AAYDARVSLA KADPLAEPWA DAMEDAYFTA FSEAEVLAHA RLAQQAGGGA 730 740 750 760 770 780 AAEGRIRSEL NAAEVVVAAA DRPRLFVDLA EAITAAGANV MGARVFTSRA GQALDVFYVQ 790 800 810 820 830 840 DASGQPFGSH DPRALARLAE TLACAARGEP VAREPRKPQD LGRTAAFAIT PAVMLDNEAS 850 860 870 880 890 900 ETSTVVEASG RDRPGLLAAL ARTISDAGLS ILSAHIDGYG ERAVDAFYVV DADGRKLTDA 910 920 930 RKRNALKSAL LAALTKAEAE TAQARRTNLQ RARASVAR

References

[1]

"Complete genome of Phenylobacterium zucineum - a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562." Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X. BMC Genomics 9:386-386(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HLK1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000747 Genomic DNA. Translation: ACG79872.1.
RefSeq	YP_002132301.1. NC_011144.1.
3D structure databases
ProteinModelPortal	B4RC79.
ModBase	Search...
Protein-protein interaction databases
STRING	450851.PHZ_c3463.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACG79872; ACG79872; PHZ_c3463.
GeneID	6789416.
KEGG	pzu:PHZ_c3463.
PATRIC	22930318. VBIPheZuc44517_4213.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261779.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK05092.
Enzyme and pathway databases
BioCyc	PZUC450851:GHUG-3508-MONOMER.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_PHEZH

Accession

Primary (citable) accession number: B4RC79

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	September 23, 2008
Last modified:	May 29, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program