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B4RC62 (B4RC62_PHEZH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209
Gene names
Name:ppa HAMAP MF_00209 EMBL ACG79855.1
Ordered Locus Names:PHZ_c3446
OrganismPhenylobacterium zucineum (strain HLK1) [Complete proteome] [HAMAP]
Taxonomic identifier450851 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Phenylobacterium

Protein attributes

Sequence length177 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209

Subcellular location

Cytoplasm By similarity HAMAP MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP MF_00209
   LigandMagnesium HAMAP MF_00209
Metal-binding HAMAP MF_00209
   Molecular functionHydrolase HAMAP MF_00209
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphate-containing compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioninorganic diphosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding661Magnesium 1 By similarity HAMAP MF_00209
Metal binding711Magnesium 1 By similarity HAMAP MF_00209
Metal binding711Magnesium 2 By similarity HAMAP MF_00209
Metal binding1031Magnesium 1 By similarity HAMAP MF_00209

Sequences

Sequence LengthMass (Da)Tools
B4RC62 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: BBCC815755CCEEBC

FASTA17719,595
        10         20         30         40         50         60 
MDLSKIPVGE NPPYDVNALI EIPQGGEPVK YEIDKESGAI FVDRFLHTAM FYPGNYGFIP 

        70         80         90        100        110        120 
HTLADDGDPM DIIVVGPTPV VPGAIIRARP VGALIMRDEA GGDEKILAVP VDKLHPFYAG 

       130        140        150        160        170 
VDSWRALPAI LTEQIAHFFK HYKDLEKGKS VDIVRWADPE EAADLIRTSI ERYKKEG

« Hide

References

[1]"Complete genome of Phenylobacterium zucineum - a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562."
Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X.
BMC Genomics 9:386-386(2008) [PubMed: 18700039] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000747 Genomic DNA. Translation: ACG79855.1.
RefSeqYP_002132284.1. NC_011144.1.

3D structure databases

ProteinModelPortalB4RC62.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4RC62.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6789399.
GenomeReviewsGene locus PHZ_c3446 in contig CP000747_GR.
KEGGpzu:PHZ_c3446.
PATRIC22930284. VBIPheZuc44517_4196.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG529150.
OMAPNDFNVI.
ProtClustDBPRK01250.

Family and domain databases

HAMAPMF_00209. Inorganic_PPase.
[Tree]
InterProIPR008162. Pyrophosphatase.
[Graphical view]
Gene3DG3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KOK01507.
PANTHERPTHR10286. Pyrophosphatase. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
PROSITEPS00387. PPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4RC62_PHEZH
AccessionPrimary (citable) accession number: B4RC62
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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