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B4RBY2 (B4RBY2_PHEZH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387 EMBL ACG78179.1
Ordered Locus Names:PHZ_c1768
OrganismPhenylobacterium zucineum (strain HLK1) [Complete proteome] [HAMAP]
Taxonomic identifier450851 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Phenylobacterium

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
B4RBY2 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 256A6A697F0DC79A

FASTA26528,325
        10         20         30         40         50         60 
MAVEIHPTAI VADSAELADG VSIGPFCIVG EAVRIGPGTR LHAHVVVEGR TTLGANNHVH 

        70         80         90        100        110        120 
PFAVLGGPPQ HTAYKGEDTE LVIGDNNLIR EHATMNIGTP HGGGVTRVGS NGLYMIESHV 

       130        140        150        160        170        180 
GHDCIVGDNV ILTKQATLGG HCQIGDYVIV GGLAAVHQFT RVGRHAMIGG LAAVVKDVIP 

       190        200        210        220        230        240 
YGSVWGNHAH LEGLNLVGLK RRGFDRETIN TLRAAYRLLF ADEGTFQERL EDTAQTYADS 

       250        260 
PQVMEIIDFI RADASRPLCL PEREV

« Hide

References

[1]"Complete genome of Phenylobacterium zucineum - a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562."
Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X.
BMC Genomics 9:386-386(2008) [PubMed: 18700039] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000747 Genomic DNA. Translation: ACG78179.1.
RefSeqYP_002130608.1. NC_011144.1.

3D structure databases

ProteinModelPortalB4RBY2.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4RBY2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6791281.
GenomeReviewsGene locus PHZ_c1768 in contig CP000747_GR.
KEGGpzu:PHZ_c1768.
PATRIC22926476. VBIPheZuc44517_2310.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG659295.
OMAREFCTFN.
ProtClustDBPRK05289.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR018357. Hexapep_transf_CS.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 2 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
PROSITEPS00101. HEXAPEP_TRANSFERASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4RBY2_PHEZH
AccessionPrimary (citable) accession number: B4RBY2
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info