B4RBY0 (B4RBY0_PHEZH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ACG78177.1

Gene names

Name:	lpxB EMBL ACG78177.1
Ordered Locus Names:	PHZ_c1766

Organism

Phenylobacterium zucineum (strain HLK1) [Complete proteome] [HAMAP]

Taxonomic identifier

450851 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Phenylobacterium

Protein attributes

Sequence length	392 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4RBY0 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 3E54B93E3C5DC788	FASTA	392	41,639
	10 20 30 40 50 60 MTAGRPLTVM LVAAEASGDD RGAGLMRALR RRLGEGVRFV GVGGERMRAE GLDSPFDIAE 70 80 90 100 110 120 LSVLGLLEGL AAYPKVIRRA REAAAIAARE KPDVAVLIDS WGFTLRVAQR LRRARPGMPL 130 140 150 160 170 180 VKYVGPQVWA SRPGRGKTTA ATYDHLLSIH AFDAPYFEAE GLPTTFVGNS ALAIDFGGAD 190 200 210 220 230 240 PARLRRSIGA GPDDPILLVL PGSRPGEIQR VLPAFEDAVL RLKAERPELH VVIPAAPTVA 250 260 270 280 290 300 DMVRARVAGW PNRAHVVEGE AGKLDAMKAA TVALACSGTV TTELALAGCP MVVGYRLAPL 310 320 330 340 350 360 TYAILKRLIT TRYVTLFNIA AGEAVAPELL QDDCNGPALA REAALRLDDA DLRRRQVERQ 370 380 390 YAALDKMGRG GPDPNEAAAS AVLKVLEGKG AA

References

[1]

"Complete genome of Phenylobacterium zucineum - a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562." Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X. BMC Genomics 9:386-386(2008) [PubMed: 18700039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000747 Genomic DNA. Translation: ACG78177.1.
RefSeq	YP_002130606.1. NC_011144.1.
3D structure databases
ProteinModelPortal	B4RBY0.
ModBase	Search...
Protein-protein interaction databases
STRING	B4RBY0.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6791279.
GenomeReviews	Gene locus PHZ_c1766 in contig CP000747_GR.
KEGG	pzu:PHZ_c1766.
PATRIC	22926472. VBIPheZuc44517_2308.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
ProtClustDB	CLSK890663.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B4RBY0_PHEZH

Accession

Primary (citable) accession number: B4RBY0

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)