B4RBL4 (DADA_PHEZH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-amino acid dehydrogenase small subunit
EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	PHZ_c0060

Organism

Phenylobacterium zucineum (strain HLK1) [Complete proteome] [HAMAP]

Taxonomic identifier

450851 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Phenylobacterium

Protein attributes

Sequence length	426 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202
Cofactor	FAD By similarity. HAMAP MF_01202
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 426	426	D-amino acid dehydrogenase small subunit HAMAP MF_01202		PRO_1000138660
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	B4RBL4 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 603C64F9A0669FFD	FASTA	426	45,586
	10 20 30 40 50 60 MKVVVLGAGV IGVTTAWYLA KAGHEVVVLE RQDGAALETS FANAGEISPG YASPWASPGV 70 80 90 100 110 120 PRKAPKWLLA RHAPLIVRPS LDPALLSWLL AMLRNCTTER YLANKARMVR LAEHSRDCLI 130 140 150 160 170 180 ALRRETGIQY DQRSRGTLQV FRTQAQMDEA GKDMEVLRDL GVPYELLDRL GCIAREPGLG 190 200 210 220 230 240 HARDTIVGGL RLPNDETGDC FKFTTALADL CRGQGVDFRF GTTIQGLETA GGEVGGVRTP 250 260 270 280 290 300 GGTVTGDAYV VCLGSYSEPF LRPHGIRTGV YPVKGYSLTA TITDEAKAPV STLLDETYKV 310 320 330 340 350 360 AITRLGDRVR IGGLAELAGY DLSLRPSRRA TLEHSAGSLF GGSCDLPSAT FWCGLRPMTP 370 380 390 400 410 420 TSTPRIGEAP LRRLFLNTGH GTLGWTMACG SAQVLADAVG RQAPALDLTD YAVPGSPAAE PLRRAA

References

[1]

"Complete genome of Phenylobacterium zucineum - a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562." Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X. BMC Genomics 9:386-386(2008) [PubMed: 18700039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HLK1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000747 Genomic DNA. Translation: ACG76474.1.
RefSeq	YP_002128903.1. NC_011144.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B4RBL4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6789548.
GenomeReviews	Gene locus PHZ_c0060 in contig CP000747_GR.
KEGG	pzu:PHZ_c0060.
PATRIC	22922628. VBIPheZuc44517_0411.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG729204.
OMA	LEHAGGQ.
Family and domain databases
HAMAP	MF_01202. DadA. [Tree]
InterPro	IPR023080. D-aa_DH_ssu_DadA. IPR006076. FAD-dep_OxRdtase. [Graphical view]
KO	K00285.
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DADA_PHEZH

Accession

Primary (citable) accession number: B4RBL4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 23, 2008
Last modified:	January 25, 2012
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program