B4RAS9 (B4RAS9_PHEZH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE-1 EMBL ACG79677.1
Synonyms:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	PHZ_c3268

Organism

Phenylobacterium zucineum (strain HLK1) [Complete proteome] [HAMAP]

Taxonomic identifier

450851 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Phenylobacterium

Protein attributes

Sequence length	1085 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4RAS9 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 1A001ED850BFB71C	FASTA	1,085	120,532
	10 20 30 40 50 60 MTRYAELQAV TNFSFLRGAS HPGDLVVAAD ALGMEAVGIC DHNSLAGVVR AWSAMRQLHE 70 80 90 100 110 120 GGSAVRALTG CRLDFVDGSP SLLVYPSDRE AYGRLTRLLT LGQRRSEKGA CTLRLADFLD 130 140 150 160 170 180 HAEGQLVLAV PPDRLDAAFG DALKRLAGDL PDVWLAAARR YGARDLKRLS HLQALAEASG 190 200 210 220 230 240 APMVATNDVL YHGPERRPLQ DVLTCIREKC TIHEAGLRLQ ANAERHLKAP DEMARLFARF 250 260 270 280 290 300 PGAVERTVEI AGRIGFDLSQ LRYEYPDEPV PPGKTAIQHL RDLAWAGAAW RYPEGVPEKV 310 320 330 340 350 360 RKLVAHELDL IEKLDFPNYF LTVHDIVRYA RDELKILCQG RGSAANSCVC FCLGITAVDP 370 380 390 400 410 420 TKEDQDLLFS RFISENRGEP PDIDVDFEHE RREEVMQYVY DRYGRDRAAI VATVIHYRPR 430 440 450 460 470 480 MAIRQVGKAL GLTEDVTAAL ANTVWGSYGD GVPDQHIRQC GLDPDAPEIR RATALAQELL 490 500 510 520 530 540 GFPRHLSQHV GGYVLTKRRL DETVPIGNAA MKDRTFIEWD KDDIDALGLM KVDVLALGML 550 560 570 580 590 600 TALRKSFELL PPLPDGTRIT DIAHVPQEDP GVYDMLCRAD SVGVFQVESR AQMSMLPRLK 610 620 630 640 650 660 PRRFYDLVVQ VAIVRPGPIQ GDMVHPYLKR RQGLEPAEFP APSPAHGPPD ELRAVLGKTY 670 680 690 700 710 720 GVPLFQEQAM RLAIEAAKFT DSEADGLRRS MATFRANGRL WEYREKFIRG MTARGYDEGF 730 740 750 760 770 780 AQRCFKQIEG FGSYGFPESH AISFALLVYA SAWVKRHHPD VFCVAMLNSQ PMGFYQPAQL 790 800 810 820 830 840 VRDAREHGVE VRPPDVMASV WDCTLEETER ASSSPVGGGG PRSGGGGLRR RPVRLGFRQI 850 860 870 880 890 900 KGFRQDDAER LVRAREAGCR TIQDFAQAAG LSRRALELLA EADAFRSLSM DRRQALWAVK 910 920 930 940 950 960 GLAGELNALE AAPLLARQSA KEQQVLLPFM SPAQHVAEDY RTTSLSLKAH PVGFFREDLN 970 980 990 1000 1010 1020 RMGAVRCGTL KDARGGRRLS VGGLVLVRQR PGTAKGVVFL TLEDETGIAN IVVWKDVFEA 1030 1040 1050 1060 1070 1080 NRRTVMTAAF LVVHGRVQSE SGVVHVVAER FTDLSERLSE MREDTAPIET RSKVSARLIR SRDFH

References

[1]

"Complete genome of Phenylobacterium zucineum - a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562." Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X. BMC Genomics 9:386-386(2008) [PubMed: 18700039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000747 Genomic DNA. Translation: ACG79677.1.
RefSeq	YP_002132106.1. NC_011144.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B4RAS9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6789219.
GenomeReviews	Gene locus PHZ_c3268 in contig CP000747_GR.
KEGG	pzu:PHZ_c3268.
PATRIC	22929894. VBIPheZuc44517_4003.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	LATNRNG.
ProtClustDB	CLSK891351.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR012340. NA-bd_OB-fold. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B4RAS9_PHEZH

Accession

Primary (citable) accession number: B4RAS9

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)