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B4R9C7 (B4R9C7_PHEZH) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase beta subunit HAMAP-Rule MF_00283

EC=6.1.1.20 HAMAP-Rule MF_00283
Alternative name(s):
Phenylalanyl-tRNA synthetase beta subunit HAMAP-Rule MF_00283
Gene names
Name:pheT HAMAP-Rule MF_00283 EMBL ACG79387.1
Ordered Locus Names:PHZ_c2978 EMBL ACG79387.1
OrganismPhenylobacterium zucineum (strain HLK1) [Complete proteome] [HAMAP] EMBL ACG79387.1
Taxonomic identifier450851 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaePhenylobacterium

Protein attributes

Sequence length807 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP-Rule MF_00283 SAAS SAAS005121

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP-Rule MF_00283 SAAS SAAS005121

Subunit structure

Tetramer of two alpha and two beta subunits By similarity. HAMAP-Rule MF_00283 SAAS SAAS005121

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00283 SAAS SAAS005121.

Sequence similarities

Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. HAMAP-Rule MF_00283

Contains 1 B5 domain. HAMAP-Rule MF_00283

Contains 1 FDX-ACB domain. HAMAP-Rule MF_00283

Contains 1 tRNA-binding domain. HAMAP-Rule MF_00283

Contains B5 domain. SAAS SAAS005121

Contains Bdomain. SAAS SAAS005121

Contains FDX-ACB domain. SAAS SAAS005121

Contains tRNA-binding domain. SAAS SAAS005121

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain39 – 148110tRNA-binding By similarity HAMAP-Rule MF_00283
Domain415 – 48672B5 By similarity HAMAP-Rule MF_00283
Domain713 – 80694FDX-ACB By similarity HAMAP-Rule MF_00283

Sites

Metal binding4641Magnesium By similarity HAMAP-Rule MF_00283
Metal binding4701Magnesium; via carbonyl oxygen By similarity HAMAP-Rule MF_00283
Metal binding4731Magnesium By similarity HAMAP-Rule MF_00283
Metal binding4741Magnesium By similarity HAMAP-Rule MF_00283

Sequences

Sequence LengthMass (Da)Tools
B4R9C7 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 02CFAD09F98C0B1D

FASTA80785,673
        10         20         30         40         50         60 
MKFTLSWLKE HLETDATVEQ VVEAMTMAGL EVESVEDPAA KLAKFTVAKI VEAVQHPNAD 

        70         80         90        100        110        120 
KLRVCQVDTK DGRLEIVCGA PNARAGLTTI YAPIGAYVPG SGITLEPRPV RGVVSNGMLC 

       130        140        150        160        170        180 
SAKELEVAEE SDGIVELPEA LPVGASAAEA FGLEAVIDFE VTPNRPDWLG VRGIARDLAA 

       190        200        210        220        230        240 
AGLGKLKPET VPQVKGSFPC PVEIRVDGTA CPVFGGRLIR GVKNGPSPEW LQKRLASVGL 

       250        260        270        280        290        300 
RPINALVDIT NFITHDRARP LHVYDRALMV GDVIEARLGK GPAEPSATDA ASPAAHKDEQ 

       310        320        330        340        350        360 
LIALDGKTYD LTPEMSIIAD ADGQRPIGLG GVMGGESTGC SETTTDVFVE CAWFDPIVTA 

       370        380        390        400        410        420 
QTGRITGINS DAQYRFARGV DPQSVVPGLE LATAMILELC GGEASEIRLA GEAPAPPAPI 

       430        440        450        460        470        480 
AFDRAYVKKL AGLDLPAQRI DAILTDLGFE VAGNAVTPPS WRRDVEGKAD LVEEVARIAG 

       490        500        510        520        530        540 
YDNLPTEPLP EVATPAGGVL TLRQRRLRDA RRSLAARGYS EAITWSFMRR AFAELFGGGQ 

       550        560        570        580        590        600 
AELVLANPIA SDLDCMRPSA LGNLIEAAAR NARRGFPDAA LFEAGPNFRG DAPGDQWTAV 

       610        620        630        640        650        660 
TALVAPHAPK SWTKTAPDPL FALKADLIAL LDELGAPQLQ VVQGQNSPWW HPGRSARLQL 

       670        680        690        700        710        720 
GPKVVVAEFG ELHPQVLKAL DAEGPMLAFE VNLDAIPEPK KKGLKTRAAL ELSPLMPLKR 

       730        740        750        760        770        780 
DFAFVVSADT PAGDLVRPIL GADKQLIADV RVFDVYQGPG VPEGQKSVAI EVTVQPREKT 

       790        800 
LTDAEIEALS ARIVAAAEKA AGAKLRG 

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References

[1]"Complete genome of Phenylobacterium zucineum - a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562."
Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X.
BMC Genomics 9:386-386(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HLK1 EMBL ACG79387.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000747 Genomic DNA. Translation: ACG79387.1.
RefSeqYP_002131816.1. NC_011144.1.

3D structure databases

ProteinModelPortalB4R9C7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING450851.PHZ_c2978.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACG79387; ACG79387; PHZ_c2978.
GeneID6788926.
KEGGpzu:PHZ_c2978.
PATRIC22929242. VBIPheZuc44517_3680.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0072.
HOGENOMHOG000292085.
KOK01890.
OMAIYVFPAD.
OrthoDBEOG6CCH1J.

Enzyme and pathway databases

BioCycPZUC450851:GHUG-3018-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
3.30.56.20. 1 hit.
3.30.70.380. 1 hit.
3.50.40.10. 1 hit.
HAMAPMF_00283. Phe_tRNA_synth_beta1.
InterProIPR005146. B3/B4_tRNA-bd.
IPR009061. DNA-bd_dom_put.
IPR012340. NA-bd_OB-fold.
IPR004532. Phe-tRNA-ligase_IIc_bsu.
IPR020825. Phe-tRNA_synthase_B3/B4.
IPR005121. PheS_beta_Fdx_antiC-bd.
IPR002547. tRNA-bd_dom.
IPR005147. tRNA_synthase_B5-dom.
[Graphical view]
PfamPF03483. B3_4. 1 hit.
PF03484. B5. 1 hit.
PF03147. FDX-ACB. 1 hit.
PF01588. tRNA_bind. 1 hit.
[Graphical view]
SMARTSM00873. B3_4. 1 hit.
SM00874. B5. 1 hit.
SM00896. FDX-ACB. 1 hit.
[Graphical view]
SUPFAMSSF46955. SSF46955. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54991. SSF54991. 1 hit.
SSF56037. SSF56037. 1 hit.
TIGRFAMsTIGR00472. pheT_bact. 1 hit.
PROSITEPS51483. B5. 1 hit.
PS51447. FDX_ACB. 1 hit.
PS50886. TRBD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4R9C7_PHEZH
AccessionPrimary (citable) accession number: B4R9C7
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)