SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B4R9C7

- B4R9C7_PHEZH

UniProt

B4R9C7 - B4R9C7_PHEZH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Phenylalanine--tRNA ligase beta subunit
Gene
pheT, PHZ_c2978
Organism
Phenylobacterium zucineum (strain HLK1)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per tetramer By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi464 – 4641Magnesium By similarityUniRule annotation
Metal bindingi470 – 4701Magnesium; via carbonyl oxygen By similarityUniRule annotation
Metal bindingi473 – 4731Magnesium By similarityUniRule annotation
Metal bindingi474 – 4741Magnesium By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. phenylalanine-tRNA ligase activity Source: UniProtKB-HAMAP
  4. tRNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. phenylalanyl-tRNA aminoacylation Source: UniProtKB-HAMAP
  2. tRNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotationSAAS annotationsImported, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations, Nucleotide-binding, RNA-binding, tRNA-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciPZUC450851:GHUG-3018-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phenylalanine--tRNA ligase beta subunitUniRule annotation (EC:6.1.1.20UniRule annotation)
Alternative name(s):
Phenylalanyl-tRNA synthetase beta subunit
Gene namesi
Name:pheTUniRule annotationImported
Ordered Locus Names:PHZ_c2978Imported
OrganismiPhenylobacterium zucineum (strain HLK1)Imported
Taxonomic identifieri450851 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaePhenylobacterium
ProteomesiUP000001868: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits By similarity.UniRule annotationSAAS annotations

Protein-protein interaction databases

STRINGi450851.PHZ_c2978.

Structurei

3D structure databases

ProteinModelPortaliB4R9C7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 148110tRNA-binding By similarityUniRule annotation
Add
BLAST
Domaini415 – 48672B5 By similarityUniRule annotation
Add
BLAST
Domaini713 – 80694FDX-ACB By similarityUniRule annotation
Add
BLAST

Sequence similaritiesi

Contains 1 B5 domain.UniRule annotation
Contains 1 FDX-ACB domain.UniRule annotation
Contains 1 tRNA-binding domain.UniRule annotation
Contains B5 domain.SAAS annotations
Contains Bdomain.SAAS annotations
Contains FDX-ACB domain.SAAS annotations
Contains tRNA-binding domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG0072.
HOGENOMiHOG000292085.
KOiK01890.
OMAiIYVFPAD.
OrthoDBiEOG6CCH1J.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.30.56.20. 1 hit.
3.30.70.380. 1 hit.
3.50.40.10. 1 hit.
HAMAPiMF_00283. Phe_tRNA_synth_beta1.
InterProiIPR005146. B3/B4_tRNA-bd.
IPR009061. DNA-bd_dom_put.
IPR012340. NA-bd_OB-fold.
IPR004532. Phe-tRNA-ligase_IIc_bsu.
IPR020825. Phe-tRNA_synthase_B3/B4.
IPR005121. PheS_beta_Fdx_antiC-bd.
IPR002547. tRNA-bd_dom.
IPR005147. tRNA_synthase_B5-dom.
[Graphical view]
PfamiPF03483. B3_4. 1 hit.
PF03484. B5. 1 hit.
PF03147. FDX-ACB. 1 hit.
PF01588. tRNA_bind. 1 hit.
[Graphical view]
SMARTiSM00873. B3_4. 1 hit.
SM00874. B5. 1 hit.
SM00896. FDX-ACB. 1 hit.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54991. SSF54991. 1 hit.
SSF56037. SSF56037. 1 hit.
TIGRFAMsiTIGR00472. pheT_bact. 1 hit.
PROSITEiPS51483. B5. 1 hit.
PS51447. FDX_ACB. 1 hit.
PS50886. TRBD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4R9C7-1 [UniParc]FASTAAdd to Basket

« Hide

MKFTLSWLKE HLETDATVEQ VVEAMTMAGL EVESVEDPAA KLAKFTVAKI    50
VEAVQHPNAD KLRVCQVDTK DGRLEIVCGA PNARAGLTTI YAPIGAYVPG 100
SGITLEPRPV RGVVSNGMLC SAKELEVAEE SDGIVELPEA LPVGASAAEA 150
FGLEAVIDFE VTPNRPDWLG VRGIARDLAA AGLGKLKPET VPQVKGSFPC 200
PVEIRVDGTA CPVFGGRLIR GVKNGPSPEW LQKRLASVGL RPINALVDIT 250
NFITHDRARP LHVYDRALMV GDVIEARLGK GPAEPSATDA ASPAAHKDEQ 300
LIALDGKTYD LTPEMSIIAD ADGQRPIGLG GVMGGESTGC SETTTDVFVE 350
CAWFDPIVTA QTGRITGINS DAQYRFARGV DPQSVVPGLE LATAMILELC 400
GGEASEIRLA GEAPAPPAPI AFDRAYVKKL AGLDLPAQRI DAILTDLGFE 450
VAGNAVTPPS WRRDVEGKAD LVEEVARIAG YDNLPTEPLP EVATPAGGVL 500
TLRQRRLRDA RRSLAARGYS EAITWSFMRR AFAELFGGGQ AELVLANPIA 550
SDLDCMRPSA LGNLIEAAAR NARRGFPDAA LFEAGPNFRG DAPGDQWTAV 600
TALVAPHAPK SWTKTAPDPL FALKADLIAL LDELGAPQLQ VVQGQNSPWW 650
HPGRSARLQL GPKVVVAEFG ELHPQVLKAL DAEGPMLAFE VNLDAIPEPK 700
KKGLKTRAAL ELSPLMPLKR DFAFVVSADT PAGDLVRPIL GADKQLIADV 750
RVFDVYQGPG VPEGQKSVAI EVTVQPREKT LTDAEIEALS ARIVAAAEKA 800
AGAKLRG 807
Length:807
Mass (Da):85,673
Last modified:September 23, 2008 - v1
Checksum:i02CFAD09F98C0B1D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000747 Genomic DNA. Translation: ACG79387.1.
RefSeqiWP_012523525.1. NC_011144.1.
YP_002131816.1. NC_011144.1.

Genome annotation databases

EnsemblBacteriaiACG79387; ACG79387; PHZ_c2978.
GeneIDi6788926.
KEGGipzu:PHZ_c2978.
PATRICi22929242. VBIPheZuc44517_3680.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000747 Genomic DNA. Translation: ACG79387.1 .
RefSeqi WP_012523525.1. NC_011144.1.
YP_002131816.1. NC_011144.1.

3D structure databases

ProteinModelPortali B4R9C7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 450851.PHZ_c2978.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACG79387 ; ACG79387 ; PHZ_c2978 .
GeneIDi 6788926.
KEGGi pzu:PHZ_c2978.
PATRICi 22929242. VBIPheZuc44517_3680.

Phylogenomic databases

eggNOGi COG0072.
HOGENOMi HOG000292085.
KOi K01890.
OMAi IYVFPAD.
OrthoDBi EOG6CCH1J.

Enzyme and pathway databases

BioCyci PZUC450851:GHUG-3018-MONOMER.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
3.30.56.20. 1 hit.
3.30.70.380. 1 hit.
3.50.40.10. 1 hit.
HAMAPi MF_00283. Phe_tRNA_synth_beta1.
InterProi IPR005146. B3/B4_tRNA-bd.
IPR009061. DNA-bd_dom_put.
IPR012340. NA-bd_OB-fold.
IPR004532. Phe-tRNA-ligase_IIc_bsu.
IPR020825. Phe-tRNA_synthase_B3/B4.
IPR005121. PheS_beta_Fdx_antiC-bd.
IPR002547. tRNA-bd_dom.
IPR005147. tRNA_synthase_B5-dom.
[Graphical view ]
Pfami PF03483. B3_4. 1 hit.
PF03484. B5. 1 hit.
PF03147. FDX-ACB. 1 hit.
PF01588. tRNA_bind. 1 hit.
[Graphical view ]
SMARTi SM00873. B3_4. 1 hit.
SM00874. B5. 1 hit.
SM00896. FDX-ACB. 1 hit.
[Graphical view ]
SUPFAMi SSF46955. SSF46955. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54991. SSF54991. 1 hit.
SSF56037. SSF56037. 1 hit.
TIGRFAMsi TIGR00472. pheT_bact. 1 hit.
PROSITEi PS51483. B5. 1 hit.
PS51447. FDX_ACB. 1 hit.
PS50886. TRBD. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome of Phenylobacterium zucineum - a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562."
    Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X.
    BMC Genomics 9:386-386(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HLK1Imported.

Entry informationi

Entry nameiB4R9C7_PHEZH
AccessioniPrimary (citable) accession number: B4R9C7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: September 3, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi