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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Phenylobacterium zucineum (strain HLK1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei139 – 1391UniRule annotation
Active sitei565 – 5651UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciPZUC450851:GHUG-1167-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:PHZ_c1154Imported
OrganismiPhenylobacterium zucineum (strain HLK1)Imported
Taxonomic identifieri450851 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaePhenylobacterium
ProteomesiUP000001868: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi450851.PHZ_c1154.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.

Sequencei

Sequence statusi: Complete.

B4R835-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQSVPDQLR AAVRFLGRVL GDVIRAQDGV AVFNQIEDIR QASVGFHREG
60 70 80 90 100
TPEAARLMAE RLGSLSLEDT VRFAHSFACF LQITNIAEDQ IQRRRIRAGE
110 120 130 140 150
ARPDTLAGAV RALAADGVER KEVEDLLAGA LIAPVITAHP SEVRRKSVLD
160 170 180 190 200
RQSAIARGLE AFDRARTDAE REAAEQELVR EVSIFWRTRL LRHVKIAVGD
210 220 230 240 250
EIENAVSYFE RSFLAALPRL YARWRHVLGQ DEALASFLRV GSWVGGDRDG
260 270 280 290 300
NPFVTAQVMR QALARQSRAA LRLYLDQVHA LGAELSISSD LAGVTPELQA
310 320 330 340 350
LADKAHDASP HRTDEPYRRA LTGVYARLAA TYPLLTGEAP PRPASTPGEP
360 370 380 390 400
YEDPQTLRAD LQTVLDSLLR MHGEAFADGP LPDLIRAVDV FGFHLATLDM
410 420 430 440 450
RQNSAVHARV AAELLRTAGV CADYEALDEA GRCQLLLSEL RHGRLLASPF
460 470 480 490 500
ATYSEETARE LEILATAAEI KRRYGPDSIR AYIVSNTTSV SDLLEVYLLL
510 520 530 540 550
KEVGLFRPGA PPTAEILAEP LFETIEDLRA APKTMARYLA LPQIHDLLAG
560 570 580 590 600
HGLQEVMIGY SDSNKDGSYL TSTWELHKTS RALASVVGGA GLRLQLFHGR
610 620 630 640 650
GGAVGRGGGS SFEALVAQPR GTVGGRIRIT EQGEVVANKY ADPELAGQSL
660 670 680 690 700
ETLTAGVVLA SLRRHASEDL AAPQTKAMDA LARHAMQAYR SLVYETPGFV
710 720 730 740 750
DYFFAATPIA EIADLNIGSR PTSRQASRSI QGLRAIPWVF SWSQSRAMLP
760 770 780 790 800
GWYGFGSAVA NGGVPMAQLR ELFESWPFFA TTLANMEMVL AKGDLAIAGR
810 820 830 840 850
YAGLVEDQAL AETVFGQIRA EWERTTEALL EITGQSALLE HNPDLAAVIR
860 870 880 890
SRLPYIDPLN HLQIELIRRR RSGDDQEAVR QGIHLTINGV AAGLRNTG
Length:898
Mass (Da):98,097
Last modified:September 23, 2008 - v1
Checksum:i6488C5163E90C13D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000747 Genomic DNA. Translation: ACG77568.1.
RefSeqiWP_012521714.1. NC_011144.1.
YP_002129997.1. NC_011144.1.

Genome annotation databases

EnsemblBacteriaiACG77568; ACG77568; PHZ_c1154.
GeneIDi6790653.
KEGGipzu:PHZ_c1154.
PATRICi22925120. VBIPheZuc44517_1646.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000747 Genomic DNA. Translation: ACG77568.1.
RefSeqiWP_012521714.1. NC_011144.1.
YP_002129997.1. NC_011144.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi450851.PHZ_c1154.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACG77568; ACG77568; PHZ_c1154.
GeneIDi6790653.
KEGGipzu:PHZ_c1154.
PATRICi22925120. VBIPheZuc44517_1646.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciPZUC450851:GHUG-1167-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome of Phenylobacterium zucineum - a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562."
    Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X.
    BMC Genomics 9:386-386(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HLK1Imported.

Entry informationi

Entry nameiB4R835_PHEZH
AccessioniPrimary (citable) accession number: B4R835
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 4, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.