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Protein
Submitted name:

HDAC6

Gene

HDAC6

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. zinc ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
HDAC6Imported
Gene namesi
Name:HDAC6Imported
Synonyms:Dsim\HDAC6Imported
ORF Names:Dsim_GD17207Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000304 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0068659. Dsim\HDAC6.

Structurei

3D structure databases

ProteinModelPortaliB4R564.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK11407.
OrthoDBiEOG7992PT.
PhylomeDBiB4R564.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
PF02148. zf-UBP. 1 hit.
[Graphical view]
PRINTSiPR01270. HDASUPER.
SMARTiSM00290. ZnF_UBP. 1 hit.
[Graphical view]
PROSITEiPS50271. ZF_UBP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B4R564-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SPPIVTRRGA QQAKIQTRAM ASKSKTGTPG APTAAGGSAG GISSSSGSIS
60 70 80 90 100
GGFNTADPRK TNKPSAALLE AKRRARNNML KNQGCGSQES VTDIFQNAVN
110 120 130 140 150
SKSMVRKPTA LIYDESMSQH CCLWDKEHYE CPERFTRVLE RCRELNLTER
160 170 180 190 200
CLELPSRSAT KDEILRLHTE EHFERLKETS GIRDDERMEE LSSRYDSIYI
210 220 230 240 250
HPPSRIQHIH KMHDDYGLLT QMKQLSARAA TTDEVCLAHT RAHVNTVRRL
260 270 280 290 300
LGREPKELHD AAGVYNSVYL HPRTFDCAVL AAGSVLQAVD SVLRGESRSG
310 320 330 340 350
ICNVRPPGHH AEQDHPHGFC IFNNVAIAAQ YAIRDFGLER VLIVDWDVHH
360 370 380 390 400
GNGTQHIFES NPKVLYISLH RYEHGSFFPK GPDGNFDVVG KGAGRGFNVN
410 420 430 440 450
IPWNKKGMGD LEYALAFQQL VMPIAYEFNP QLVLVSAGFD AAIGDPLGGC
460 470 480 490 500
KVTPEGYGML THWLSALASG RIIVCLEGGY NVNSISYAMT MCTKTLLGDP
510 520 530 540 550
VPTPQLGATA LQKPPTVAFQ SCVESLQLCL QVQRTHWRSL EFVGRRLPRD
560 570 580 590 600
PVVGENNNED FLTASLRHLN ISNDDATVAA SGPAVDRPDC GDERPSGSKP
610 620 630 640 650
KVKVKTLSDY LADNKEALEQ SEMFAVYPLK TCPHLRLLRP EEAPRSLDSR
660 670 680 690 700
AECSVCGSTG ENWVCLSCRH VACGRYVNAH MEQHSVEEQH PLAMSTADLS
710 720 730 740 750
VWCYACSAYV DHPRLYAYLN PLHVDKFQEP MAWTHGCACR EDGCYATGPD
760 770
GRDEDDENND DDNVAGSSIC LRLERNN
Length:777
Mass (Da):85,842
Last modified:September 22, 2008 - v1
Checksum:i2EA879D7E42FA3CE
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000366 Genomic DNA. Translation: EDX17965.1.
RefSeqiXP_002106992.1. XM_002106956.1.

Genome annotation databases

EnsemblMetazoaiFBtr0217117; FBpp0215609; FBgn0068659.
GeneIDi6726010.
KEGGidsi:Dsim_GD17207.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000366 Genomic DNA. Translation: EDX17965.1.
RefSeqiXP_002106992.1. XM_002106956.1.

3D structure databases

ProteinModelPortaliB4R564.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0217117; FBpp0215609; FBgn0068659.
GeneIDi6726010.
KEGGidsi:Dsim_GD17207.

Organism-specific databases

FlyBaseiFBgn0068659. Dsim\HDAC6.

Phylogenomic databases

KOiK11407.
OrthoDBiEOG7992PT.
PhylomeDBiB4R564.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
PF02148. zf-UBP. 1 hit.
[Graphical view]
PRINTSiPR01270. HDASUPER.
SMARTiSM00290. ZnF_UBP. 1 hit.
[Graphical view]
PROSITEiPS50271. ZF_UBP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MixedImported.

Entry informationi

Entry nameiB4R564_DROSI
AccessioniPrimary (citable) accession number: B4R564
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2008
Last sequence update: September 22, 2008
Last modified: March 31, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.