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B4R4C9

- B4R4C9_DROSI

UniProt

B4R4C9 - B4R4C9_DROSI

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Protein
Submitted name:

GD17127

Gene

Dsim\GD17127

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. histone-lysine N-methyltransferase activity Source: InterPro

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
GD17127Imported
Gene namesi
Name:Dsim\GD17127Imported
ORF Names:Dsim_GD17127Imported, GD17127Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000304: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0188697. Dsim\GD17127.

Subcellular locationi

GO - Cellular componenti

  1. chromosome Source: InterPro
  2. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Phylogenomic databases

KOiK11423.
OrthoDBiEOG7DFXBB.
PhylomeDBiB4R4C9.

Family and domain databases

InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS_dom.
IPR000742. EG-like_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR013257. SRI.
IPR001202. WW_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
PF08236. SRI. 1 hit.
PF00397. WW. 1 hit.
[Graphical view]
SMARTiSM00384. AT_hook. 2 hits.
SM00570. AWS. 1 hit.
SM00181. EGF. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4R4C9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEESVPPSNP SPVASRGRGR GRPPKVTNTP PHINPAMKSA DAGASPTPPE
60 70 80 90 100
DQDSGQSECR RSSRKKIIKF DVRDLLNKNR KAHKIQIEAR IDSNPTATVN
110 120 130 140 150
RLFSMFEMSH QSLPLPPPPP PALEIFAKPR PTQSLIVAQV TSEPSAAGGG
160 170 180 190 200
QPVQTMAGLS PLTPRKRGRP RKSQQADAAI IPTVIVPSCS DSDTNSTSTT
210 220 230 240 250
TSNMSSDSGD LPGFPIRKPK SKLRVSLKRL KLCGRLASSD SGNSPSSSSP
260 270 280 290 300
EVEPPALQDE NAMDERPKQE QNLTRIVVAE ENSDSDSQII FIEIETESPK
310 320 330 340 350
GQEEQEEERP VEVEPQDLID IDMELAKQEP TPDPEEDLDE IMVEVLSGPP
360 370 380 390 400
SLWSADDEAE EEEDATVQRA TPPEKEPAAD SCSSAPRRSR RSAPLSGSSR
410 420 430 440 450
QGKTLEETFA EIAAESSKQI LEAEESQDQE EEHILIDLIE DTLSEPEVTS
460 470 480 490 500
SVSPTIEHMV VEEVVVEENQ LVDEADAILD SKQEFVINKV FSESDKIAAS
510 520 530 540 550
LNKDICKPKV ETKDTPGEVV PRPELVTEDV YITHGIAATL EKSSLATEQT
560 570 580 590 600
TEINAKTKLS LDVVIEPPLK DEDDPNPTEV ELPESKPAVN IPKSDRTLLA
610 620 630 640 650
EVETKPSPLV QPECDTLGKV SGKVLLESSL STEEKSNENI DTTALKTEAA
660 670 680 690 700
KEAASEEETS NNSEEPNSLL EDFEINQVQE QNILADDEMV KCNDQKEQKK
710 720 730 740 750
TPLPEMKERK KPLAGDVSKK EKVMEKPARS SPAIVDKKVR AGEIDKKVVK
760 770 780 790 800
STKGTVPEKK MDTKKSCPAV TPGKQKESGK SAKEAILKKE TEKDKLSSTQ
810 820 830 840 850
TLDKKGKDTA QWPPKALQES APSAISKSTS NQSAPKEEQH AAKKSLSDNS
860 870 880 890 900
TSAVLKAKEK AVSGFVECDA MFKAMDLANA QLRLEEKNKK KQKKVPPKVE
910 920 930 940 950
APPKVDPPTA VPVPGQKKSL AGKTSLRRNT VYEDSPKLER NSSPGSDSAQ
960 970 980 990 1000
ANTSAGKLKP SKPKKKINPR RSTICEAAKD LRSSSSSSTP TREVAASSPI
1010 1020 1030 1040 1050
STSSDSSSKR NGSKRTTSDL AGGSKLDQRR YTICEDRQPE TAIPVPLTKR
1060 1070 1080 1090 1100
RFSMHPKASA NPLHDTLLQS AGKKRGRKEG KEPLSRQNSL DSSSSASQGV
1110 1120 1130 1140 1150
PKKKAQKSAE VLNAALLETE SSESTSSGSK MSRWDVQTSP ELEAANPFGD
1160 1170 1180 1190 1200
IAKFIEDGVN LLKRDKVDEE QRKEGQDEVK READPEEDEF AQRVANMETP
1210 1220 1230 1240 1250
ATTPTPSPTQ SSPEDSASTT TTLKALETSG GVRRSHRIKQ KPQGQRASQG
1260 1270 1280 1290 1300
RGVASMALAP ISMDEQLAEL ANIEAINEQF LRSEGLNTFQ LLKENFYRCA
1310 1320 1330 1340 1350
RQVSQENAEM QCDCFLTGDE EAQGHLSCGA GCINRMLMIE CGPLCSNGAR
1360 1370 1380 1390 1400
CTNKRFQQHQ CWPCRVFRTE KKGCGITAEL LIPPGEFIME YVGEVIDSEE
1410 1420 1430 1440 1450
FERRQHLYSK DRNRHYYFMA LRGEAVIDAT SKGNISRYIN HSCDPNAETQ
1460 1470 1480 1490 1500
KWTVNGELRI GFFSVKPIQP GEEITFDYQY LRYGRDAQRC YCESTNCRGW
1510 1520 1530 1540 1550
IGGEPDSDEG EQLDEKATAM LRWTRRSWKP SRRRAMLEDP DVVEELSLLR
1560 1570 1580 1590 1600
RGGLKNQQDT LRFSRCLVRA KLLKTRLGLL RVLTHGELPC RRLFLDYHGL
1610 1620 1630 1640 1650
RLLHAWISEN GNDEQLREAL LDTLESLPIP NRTMLSDSRV YQNVQLWSNS
1660 1670 1680 1690 1700
LEQQQAVVPE PKQAALHKRM VALLQKWQAL PEIFRIPKRE RIEQMKEHER
1710 1720 1730 1740 1750
EADRQQKQVH ASTALEDQRE RESSNDRFRQ DRFRRDTTGS RIGKPTRMSG
1760 1770 1780 1790 1800
NNTICTITTQ QKGSNGATDG MARNDNRRRS DIGPSSEQKR TLSKELRRSL
1810 1820 1830 1840 1850
FERKVALDEA ERRVCTEDRL EHELRCEFFG ADINTDPKQL PFYQKTDTNE
1860 1870 1880 1890 1900
WFNSDDRPVP APPRTGLLTK ALLSPDIDIG QGAPDVEYKL PPGVDPLPPA
1910 1920 1930 1940 1950
WNWQVTSDGD IYYYNLRQRI SQWEPPSPEQ RLQTLLEENS TQQPLHELQI
1960 1970 1980 1990 2000
EPAVLENELI QIDTDYVGSL STKSLAQYIE AKVRERRELR RGKLVSIRLI
2010 2020 2030 2040 2050
SPRRDEDRLY NQLESRKYKE NKEKIRRRKE LYRRRKLEAL PDAIDDIPVP
2060 2070 2080 2090 2100
GQALPIQPYL YSSDEEETKV PAMEEPAAKE EQQDSLNMAP STSHAAMAAL
2110 2120 2130 2140 2150
VKVVAQPNGL GAAGKRKLPM PPNVSMKKHR QEHKNKKSKS SQSPLTAASA
2160 2170 2180 2190 2200
REAHEKFRFE ISGHVANFLR PYRKESCLLG RITTDEDYKF LVNRLSYHIT
2210 2220 2230 2240
TKEMRYCEVS GNPLSCTESV KHKSYDFVNQ YMRQKGLVYR RPAEKE
Length:2,246
Mass (Da):250,931
Last modified:September 23, 2008 - v1
Checksum:i8F4F058203664174
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000366 Genomic DNA. Translation: EDX17831.1.
RefSeqiXP_002106863.1. XM_002106827.1.

Genome annotation databases

EnsemblMetazoaiFBtr0217037; FBpp0215529; FBgn0188697.
GeneIDi6725867.
KEGGidsi:Dsim_GD17127.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000366 Genomic DNA. Translation: EDX17831.1 .
RefSeqi XP_002106863.1. XM_002106827.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0217037 ; FBpp0215529 ; FBgn0188697 .
GeneIDi 6725867.
KEGGi dsi:Dsim_GD17127.

Organism-specific databases

FlyBasei FBgn0188697. Dsim\GD17127.

Phylogenomic databases

KOi K11423.
OrthoDBi EOG7DFXBB.
PhylomeDBi B4R4C9.

Family and domain databases

InterProi IPR017956. AT_hook_DNA-bd_motif.
IPR006560. AWS_dom.
IPR000742. EG-like_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR013257. SRI.
IPR001202. WW_dom.
[Graphical view ]
Pfami PF00856. SET. 1 hit.
PF08236. SRI. 1 hit.
PF00397. WW. 1 hit.
[Graphical view ]
SMARTi SM00384. AT_hook. 2 hits.
SM00570. AWS. 1 hit.
SM00181. EGF. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
SM00456. WW. 1 hit.
[Graphical view ]
SUPFAMi SSF51045. SSF51045. 1 hit.
PROSITEi PS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MixedImported.

Entry informationi

Entry nameiB4R4C9_DROSI
AccessioniPrimary (citable) accession number: B4R4C9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3