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B4R4C9

- B4R4C9_DROSI

UniProt

B4R4C9 - B4R4C9_DROSI

Protein
Submitted name:

GD17127

Gene

Dsim\GD17127

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. histone-lysine N-methyltransferase activity Source: InterPro

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: InterPro

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationSAAS annotation, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionineSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    GD17127Imported
    Gene namesi
    Name:Dsim\GD17127Imported
    ORF Names:Dsim_GD17127Imported, GD17127Imported
    OrganismiDrosophila simulans (Fruit fly)Imported
    Taxonomic identifieri7240 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000304: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0188697. Dsim\GD17127.

    Subcellular locationi

    GO - Cellular componenti

    1. chromosome Source: InterPro
    2. nucleus Source: UniProtKB-KW

    Keywords - Cellular componenti

    NucleusSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation
    Contains SET domain.SAAS annotation
    Contains post-SET domain.SAAS annotation

    Phylogenomic databases

    KOiK11423.
    OrthoDBiEOG7DFXBB.
    PhylomeDBiB4R4C9.

    Family and domain databases

    InterProiIPR017956. AT_hook_DNA-bd_motif.
    IPR006560. AWS.
    IPR000742. EG-like_dom.
    IPR003616. Post-SET_dom.
    IPR001214. SET_dom.
    IPR013257. SRI.
    IPR001202. WW_dom.
    [Graphical view]
    PfamiPF00856. SET. 1 hit.
    PF08236. SRI. 1 hit.
    PF00397. WW. 1 hit.
    [Graphical view]
    SMARTiSM00384. AT_hook. 2 hits.
    SM00570. AWS. 1 hit.
    SM00181. EGF. 1 hit.
    SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    SM00456. WW. 1 hit.
    [Graphical view]
    SUPFAMiSSF51045. SSF51045. 1 hit.
    PROSITEiPS51215. AWS. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50280. SET. 1 hit.
    PS01159. WW_DOMAIN_1. 1 hit.
    PS50020. WW_DOMAIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4R4C9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEESVPPSNP SPVASRGRGR GRPPKVTNTP PHINPAMKSA DAGASPTPPE     50
    DQDSGQSECR RSSRKKIIKF DVRDLLNKNR KAHKIQIEAR IDSNPTATVN 100
    RLFSMFEMSH QSLPLPPPPP PALEIFAKPR PTQSLIVAQV TSEPSAAGGG 150
    QPVQTMAGLS PLTPRKRGRP RKSQQADAAI IPTVIVPSCS DSDTNSTSTT 200
    TSNMSSDSGD LPGFPIRKPK SKLRVSLKRL KLCGRLASSD SGNSPSSSSP 250
    EVEPPALQDE NAMDERPKQE QNLTRIVVAE ENSDSDSQII FIEIETESPK 300
    GQEEQEEERP VEVEPQDLID IDMELAKQEP TPDPEEDLDE IMVEVLSGPP 350
    SLWSADDEAE EEEDATVQRA TPPEKEPAAD SCSSAPRRSR RSAPLSGSSR 400
    QGKTLEETFA EIAAESSKQI LEAEESQDQE EEHILIDLIE DTLSEPEVTS 450
    SVSPTIEHMV VEEVVVEENQ LVDEADAILD SKQEFVINKV FSESDKIAAS 500
    LNKDICKPKV ETKDTPGEVV PRPELVTEDV YITHGIAATL EKSSLATEQT 550
    TEINAKTKLS LDVVIEPPLK DEDDPNPTEV ELPESKPAVN IPKSDRTLLA 600
    EVETKPSPLV QPECDTLGKV SGKVLLESSL STEEKSNENI DTTALKTEAA 650
    KEAASEEETS NNSEEPNSLL EDFEINQVQE QNILADDEMV KCNDQKEQKK 700
    TPLPEMKERK KPLAGDVSKK EKVMEKPARS SPAIVDKKVR AGEIDKKVVK 750
    STKGTVPEKK MDTKKSCPAV TPGKQKESGK SAKEAILKKE TEKDKLSSTQ 800
    TLDKKGKDTA QWPPKALQES APSAISKSTS NQSAPKEEQH AAKKSLSDNS 850
    TSAVLKAKEK AVSGFVECDA MFKAMDLANA QLRLEEKNKK KQKKVPPKVE 900
    APPKVDPPTA VPVPGQKKSL AGKTSLRRNT VYEDSPKLER NSSPGSDSAQ 950
    ANTSAGKLKP SKPKKKINPR RSTICEAAKD LRSSSSSSTP TREVAASSPI 1000
    STSSDSSSKR NGSKRTTSDL AGGSKLDQRR YTICEDRQPE TAIPVPLTKR 1050
    RFSMHPKASA NPLHDTLLQS AGKKRGRKEG KEPLSRQNSL DSSSSASQGV 1100
    PKKKAQKSAE VLNAALLETE SSESTSSGSK MSRWDVQTSP ELEAANPFGD 1150
    IAKFIEDGVN LLKRDKVDEE QRKEGQDEVK READPEEDEF AQRVANMETP 1200
    ATTPTPSPTQ SSPEDSASTT TTLKALETSG GVRRSHRIKQ KPQGQRASQG 1250
    RGVASMALAP ISMDEQLAEL ANIEAINEQF LRSEGLNTFQ LLKENFYRCA 1300
    RQVSQENAEM QCDCFLTGDE EAQGHLSCGA GCINRMLMIE CGPLCSNGAR 1350
    CTNKRFQQHQ CWPCRVFRTE KKGCGITAEL LIPPGEFIME YVGEVIDSEE 1400
    FERRQHLYSK DRNRHYYFMA LRGEAVIDAT SKGNISRYIN HSCDPNAETQ 1450
    KWTVNGELRI GFFSVKPIQP GEEITFDYQY LRYGRDAQRC YCESTNCRGW 1500
    IGGEPDSDEG EQLDEKATAM LRWTRRSWKP SRRRAMLEDP DVVEELSLLR 1550
    RGGLKNQQDT LRFSRCLVRA KLLKTRLGLL RVLTHGELPC RRLFLDYHGL 1600
    RLLHAWISEN GNDEQLREAL LDTLESLPIP NRTMLSDSRV YQNVQLWSNS 1650
    LEQQQAVVPE PKQAALHKRM VALLQKWQAL PEIFRIPKRE RIEQMKEHER 1700
    EADRQQKQVH ASTALEDQRE RESSNDRFRQ DRFRRDTTGS RIGKPTRMSG 1750
    NNTICTITTQ QKGSNGATDG MARNDNRRRS DIGPSSEQKR TLSKELRRSL 1800
    FERKVALDEA ERRVCTEDRL EHELRCEFFG ADINTDPKQL PFYQKTDTNE 1850
    WFNSDDRPVP APPRTGLLTK ALLSPDIDIG QGAPDVEYKL PPGVDPLPPA 1900
    WNWQVTSDGD IYYYNLRQRI SQWEPPSPEQ RLQTLLEENS TQQPLHELQI 1950
    EPAVLENELI QIDTDYVGSL STKSLAQYIE AKVRERRELR RGKLVSIRLI 2000
    SPRRDEDRLY NQLESRKYKE NKEKIRRRKE LYRRRKLEAL PDAIDDIPVP 2050
    GQALPIQPYL YSSDEEETKV PAMEEPAAKE EQQDSLNMAP STSHAAMAAL 2100
    VKVVAQPNGL GAAGKRKLPM PPNVSMKKHR QEHKNKKSKS SQSPLTAASA 2150
    REAHEKFRFE ISGHVANFLR PYRKESCLLG RITTDEDYKF LVNRLSYHIT 2200
    TKEMRYCEVS GNPLSCTESV KHKSYDFVNQ YMRQKGLVYR RPAEKE 2246
    Length:2,246
    Mass (Da):250,931
    Last modified:September 23, 2008 - v1
    Checksum:i8F4F058203664174
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000366 Genomic DNA. Translation: EDX17831.1.
    RefSeqiXP_002106863.1. XM_002106827.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0217037; FBpp0215529; FBgn0188697.
    GeneIDi6725867.
    KEGGidsi:Dsim_GD17127.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000366 Genomic DNA. Translation: EDX17831.1 .
    RefSeqi XP_002106863.1. XM_002106827.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0217037 ; FBpp0215529 ; FBgn0188697 .
    GeneIDi 6725867.
    KEGGi dsi:Dsim_GD17127.

    Organism-specific databases

    FlyBasei FBgn0188697. Dsim\GD17127.

    Phylogenomic databases

    KOi K11423.
    OrthoDBi EOG7DFXBB.
    PhylomeDBi B4R4C9.

    Family and domain databases

    InterProi IPR017956. AT_hook_DNA-bd_motif.
    IPR006560. AWS.
    IPR000742. EG-like_dom.
    IPR003616. Post-SET_dom.
    IPR001214. SET_dom.
    IPR013257. SRI.
    IPR001202. WW_dom.
    [Graphical view ]
    Pfami PF00856. SET. 1 hit.
    PF08236. SRI. 1 hit.
    PF00397. WW. 1 hit.
    [Graphical view ]
    SMARTi SM00384. AT_hook. 2 hits.
    SM00570. AWS. 1 hit.
    SM00181. EGF. 1 hit.
    SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    SM00456. WW. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51045. SSF51045. 1 hit.
    PROSITEi PS51215. AWS. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50280. SET. 1 hit.
    PS01159. WW_DOMAIN_1. 1 hit.
    PS50020. WW_DOMAIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MixedImported.

    Entry informationi

    Entry nameiB4R4C9_DROSI
    AccessioniPrimary (citable) accession number: B4R4C9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3