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B4R318

- B4R318_DROSI

UniProt

B4R318 - B4R318_DROSI

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Protein
Submitted name:

GD16408

Gene

Dsim\GD16408

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: InterPro
  2. zinc ion binding Source: InterPro

GO - Biological processi

  1. histone H3-K4 methylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
GD16408Imported
Gene namesi
Name:Dsim\GD16408Imported
ORF Names:Dsim_GD16408Imported, GD16408Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000304: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0188025. Dsim\GD16408.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Phylogenomic databases

KOiK09188.
OrthoDBiEOG7QZG8S.
PhylomeDBiB4R318.

Family and domain databases

InterProiIPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR015722. Histone-lys_MeTfrase_Trr.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR001965. Znf_PHD.
[Graphical view]
PANTHERiPTHR22884:SF297. PTHR22884:SF297. 1 hit.
PfamiPF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4R318-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQPLQVLEPH LNRNFHFLIG SNETSGAGSP ASMSSAASAG SSSAGGGKLK
60 70 80 90 100
GGSRGWPLSR HLEGLEDCDG TVLGRYGRVN LPGIPSLYDS ERFGGSRGLV
110 120 130 140 150
GGSAGTRSPS PAESPGAEKM LPMSSIQNDF YDQEFSTHME RNPRERLVRH
160 170 180 190 200
IGAVKDCNLE TVDLVESEGV AAWATLPRLT RYPGLILLNG NSRCHGRMSP
210 220 230 240 250
VALPEDPLTM RFPVSPLLRS CGEELRKTQQ MELGMGPLGN NNNNYQQKNQ
260 270 280 290 300
NVILALPASA SENIAGVLRD LANLLHLAPA LTCKIIEDKI GNKLEDQFMN
310 320 330 340 350
QDDEKHVDFK RPPSQVSHGH LRKILNGRRK LCRSCGNVVH ATGLRVPRHS
360 370 380 390 400
VPALEEQLPR LAQLMDMLPR KSVPPPFVYF CDRACFARFK WNGKDGQAEA
410 420 430 440 450
ASLLLQPAGG SAVKSSNGDL PGSFCASSTA PAEMVVKQEP EDEDEKTQGV
460 470 480 490 500
PGNPTNIPAQ RKCIVKCFSA DCFTTDSASS GLELDGTADA GTGAGPVNNT
510 520 530 540 550
VWETETSGLQ LEDTRQCVFC NQRGDGQADG PSRLLNFDVD KWVHLNCALW
560 570 580 590 600
SNGVYETVSG ALMNFQTALH AGLNQACSAC HQLGATIKCF KSRCNSLYHL
610 620 630 640 650
PCAIREECVF YKNKSVHCSV HGHAHAGITM GAGAGATTGA GVEGFVAENE
660 670 680 690 700
LSSLVVHRRV FVDRDENRQV PTVMHYSELS NLFRVGNMTF LNVGQLLPHQ
710 720 730 740 750
LEAFHTPHYI YPIGYKVSRY YWCVRRPNRR CRYICSIAEA GCKPEFRIQV
760 770 780 790 800
QDAGDKEPER EFRGSSPSAV WQQILQPITR LRKVHKWLQL FPQHISGEDL
810 820 830 840 850
FGLTEPAIVR ILESLPGIET LTDYRFKYGR NPLLEFPLAI NPSGAARTEP
860 870 880 890 900
KQRQLLVWRK PHTQRTAGSC STQRMANSAA IAGEVACPYS KQFVHSKSSQ
910 920 930 940 950
YKKMKQEWRN NVYLASKQFV HSKSSQYKKM KQEWRNNVYL ARSKIQGLGL
960 970 980 990 1000
YAARDIEKHT MIIEYIGEVI RTEVSEIREK QYESKNRGIY MFRLDEDRVV
1010 1020 1030 1040 1050
DATLSGGLAR YINHSCNPNC VTEIVEVDRD VRIIIFAKRK IYRGEELSYD
1060 1070
YKFDIEDESH KIPCACGAPN CRKWMN
Length:1,076
Mass (Da):119,545
Last modified:September 23, 2008 - v1
Checksum:i3C2BFE4ACFB0F725
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000366 Genomic DNA. Translation: EDX16872.1.
RefSeqiXP_002105931.1. XM_002105895.1.

Genome annotation databases

EnsemblMetazoaiFBtr0216318; FBpp0214810; FBgn0188025.
GeneIDi6724893.
KEGGidsi:Dsim_GD16408.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000366 Genomic DNA. Translation: EDX16872.1 .
RefSeqi XP_002105931.1. XM_002105895.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0216318 ; FBpp0214810 ; FBgn0188025 .
GeneIDi 6724893.
KEGGi dsi:Dsim_GD16408.

Organism-specific databases

FlyBasei FBgn0188025. Dsim\GD16408.

Phylogenomic databases

KOi K09188.
OrthoDBi EOG7QZG8S.
PhylomeDBi B4R318.

Family and domain databases

InterProi IPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR015722. Histone-lys_MeTfrase_Trr.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR001965. Znf_PHD.
[Graphical view ]
PANTHERi PTHR22884:SF297. PTHR22884:SF297. 1 hit.
Pfami PF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
PROSITEi PS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MixedImported.

Entry informationi

Entry nameiB4R318_DROSI
AccessioniPrimary (citable) accession number: B4R318
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 1, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3