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B4R089

- PTC71_DROSI

UniProt

B4R089 - PTC71_DROSI

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Protein

Protein phosphatase PTC7 homolog fig

Gene
fig, GD17671
Organism
Drosophila simulans (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Magnesium or manganese Reviewed prediction.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi87 – 871Manganese 1 By similarityBy similarity
Metal bindingi87 – 871Manganese 2 By similarityBy similarity
Metal bindingi88 – 881Manganese 1; via carbonyl oxygen By similarityBy similarity
Metal bindingi232 – 2321Manganese 2 By similarityBy similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: UniProtKB

GO - Biological processi

  1. dephosphorylation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase PTC7 homolog fig
Alternative name(s):
Fos intronic gene protein (EC:3.1.3.16)
Gene namesi
Name:fig
ORF Names:GD17671
OrganismiDrosophila simulans (Fruit fly)
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000304: Chromosome 3R, UP000000304: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0189220. Dsim\GD17671.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 314314Protein phosphatase PTC7 homolog figPRO_0000377403Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliB4R089.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini52 – 307256PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.
Contains 1 PP2C-like domain.

Phylogenomic databases

KOiK17508.
OrthoDBiEOG7DRJ3F.
PhylomeDBiB4R089.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
[Graphical view]
PfamiPF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequencei

Sequence statusi: Complete.

B4R089-1 [UniParc]FASTAAdd to Basket

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MITRMKNWPC LLKRFSIQQF HQFTHLSGRL ERAPQSGKSS RDPYLVTVVQ    50
GRSKKPRFPG ERSNQRFGED SWFVSSTPLA EVMGVADGVG GWRDLGVDAG 100
RFAKELMSCC SGQTQLSDFD GRSPRNLLIA GFQELSHREQ PVVGSSTACL 150
ATMHRKDCTL YTANLGDSGF LVVRNGRVLH RSVEQTHDFN TPYQLTVPPE 200
DRKESYYCDK PEMAVSTRHS LLPGDLVLLA TDGLFDNMPE STLLSILNGL 250
KERGERDLLE GASRVVEKAR ELSLNASFQS PFAIKARQHN VSYSGGGKPD 300
DITLILSSVE VPSV 314
Length:314
Mass (Da):34,834
Last modified:September 23, 2008 - v1
Checksum:i8E662288B5A5052B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000364 Genomic DNA. Translation: EDX14895.1.
RefSeqiXP_002105392.1. XM_002105356.1.
UniGeneiDsi.1113.

Genome annotation databases

EnsemblMetazoaiFBtr0217581; FBpp0216073; FBgn0189220.
GeneIDi6730099.
KEGGidsi:Dsim_GD17671.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000364 Genomic DNA. Translation: EDX14895.1 .
RefSeqi XP_002105392.1. XM_002105356.1.
UniGenei Dsi.1113.

3D structure databases

ProteinModelPortali B4R089.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0217581 ; FBpp0216073 ; FBgn0189220 .
GeneIDi 6730099.
KEGGi dsi:Dsim_GD17671.

Organism-specific databases

FlyBasei FBgn0189220. Dsim\GD17671.

Phylogenomic databases

KOi K17508.
OrthoDBi EOG7DRJ3F.
PhylomeDBi B4R089.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
[Graphical view ]
Pfami PF07228. SpoIIE. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiPTC71_DROSI
AccessioniPrimary (citable) accession number: B4R089
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: September 23, 2008
Last modified: July 9, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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