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B4R089

- PTC71_DROSI

UniProt

B4R089 - PTC71_DROSI

Protein

Protein phosphatase PTC7 homolog fig

Gene

fig

Organism
Drosophila simulans (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Magnesium or manganese.By similarityCurated

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi87 – 871Manganese 1By similarity
    Metal bindingi87 – 871Manganese 2By similarity
    Metal bindingi88 – 881Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi232 – 2321Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: UniProtKB

    GO - Biological processi

    1. dephosphorylation Source: UniProtKB

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein phosphatase PTC7 homolog fig
    Alternative name(s):
    Fos intronic gene protein (EC:3.1.3.16)
    Gene namesi
    Name:figBy similarity
    ORF Names:GD17671
    OrganismiDrosophila simulans (Fruit fly)
    Taxonomic identifieri7240 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000304: Chromosome 3R, UP000000304: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0189220. Dsim\GD17671.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 314314Protein phosphatase PTC7 homolog figPRO_0000377403Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliB4R089.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini52 – 307256PP2C-likeSequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Sequence Analysis
    Contains 1 PP2C-like domain.Sequence Analysis

    Phylogenomic databases

    KOiK17508.
    OrthoDBiEOG7DRJ3F.
    PhylomeDBiB4R089.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    [Graphical view]
    PfamiPF07228. SpoIIE. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4R089-1 [UniParc]FASTAAdd to Basket

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    MITRMKNWPC LLKRFSIQQF HQFTHLSGRL ERAPQSGKSS RDPYLVTVVQ    50
    GRSKKPRFPG ERSNQRFGED SWFVSSTPLA EVMGVADGVG GWRDLGVDAG 100
    RFAKELMSCC SGQTQLSDFD GRSPRNLLIA GFQELSHREQ PVVGSSTACL 150
    ATMHRKDCTL YTANLGDSGF LVVRNGRVLH RSVEQTHDFN TPYQLTVPPE 200
    DRKESYYCDK PEMAVSTRHS LLPGDLVLLA TDGLFDNMPE STLLSILNGL 250
    KERGERDLLE GASRVVEKAR ELSLNASFQS PFAIKARQHN VSYSGGGKPD 300
    DITLILSSVE VPSV 314
    Length:314
    Mass (Da):34,834
    Last modified:September 23, 2008 - v1
    Checksum:i8E662288B5A5052B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000364 Genomic DNA. Translation: EDX14895.1.
    RefSeqiXP_002105392.1. XM_002105356.1.
    UniGeneiDsi.1113.

    Genome annotation databases

    EnsemblMetazoaiFBtr0217581; FBpp0216073; FBgn0189220.
    GeneIDi6730099.
    KEGGidsi:Dsim_GD17671.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000364 Genomic DNA. Translation: EDX14895.1 .
    RefSeqi XP_002105392.1. XM_002105356.1.
    UniGenei Dsi.1113.

    3D structure databases

    ProteinModelPortali B4R089.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0217581 ; FBpp0216073 ; FBgn0189220 .
    GeneIDi 6730099.
    KEGGi dsi:Dsim_GD17671.

    Organism-specific databases

    FlyBasei FBgn0189220. Dsim\GD17671.

    Phylogenomic databases

    KOi K17508.
    OrthoDBi EOG7DRJ3F.
    PhylomeDBi B4R089.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    [Graphical view ]
    Pfami PF07228. SpoIIE. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiPTC71_DROSI
    AccessioniPrimary (citable) accession number: B4R089
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programDrosophila annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Drosophila
      Drosophila: entries, gene names and cross-references to FlyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3