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Protein

Delta-like protein

Gene

Dsim\GD18089

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Putative Notch ligand involved in the mediation of Notch signaling.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Delta-like proteinUniRule annotation
Gene namesi
Name:Dsim\GD18089Imported
ORF Names:Dsim_GD18089Imported, GD18089Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000304 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0189632. Dsim\GD18089.

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1203 – 1226HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini241 – 285DSLInterPro annotationAdd BLAST45
Domaini286 – 319EGF-likeInterPro annotationAdd BLAST34
Domaini353 – 391EGF-likeInterPro annotationAdd BLAST39
Domaini452 – 491EGF-likeInterPro annotationAdd BLAST40
Domaini493 – 529EGF-likeInterPro annotationAdd BLAST37
Domaini573 – 611EGF-likeInterPro annotationAdd BLAST39
Domaini613 – 648EGF-likeInterPro annotationAdd BLAST36
Domaini650 – 686EGF-likeInterPro annotationAdd BLAST37
Domaini688 – 723EGF-likeInterPro annotationAdd BLAST36
Domaini741 – 777EGF-likeInterPro annotationAdd BLAST37
Domaini779 – 815EGF-likeInterPro annotationAdd BLAST37
Domaini817 – 857EGF-likeInterPro annotationAdd BLAST41
Domaini859 – 895EGF-likeInterPro annotationAdd BLAST37
Domaini897 – 933EGF-likeInterPro annotationAdd BLAST37

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation, SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiB4QXF3.

Family and domain databases

InterProiIPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR011651. Notch_ligand_N.
IPR001007. VWF_dom.
[Graphical view]
PfamiPF01414. DSL. 1 hit.
PF00008. EGF. 6 hits.
PF07645. EGF_CA. 1 hit.
PF12661. hEGF. 2 hits.
PF07657. MNNL. 1 hit.
[Graphical view]
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiSM00051. DSL. 1 hit.
SM00181. EGF. 14 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 8 hits.
PS50026. EGF_3. 13 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4QXF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKMFRKHFR RKPATSTSLS SSESTIESPD SLGMSKKTAT KRQRPRHRAP
60 70 80 90 100
KIATLPSTIR DCRSLKSACN LIALILILLV HKISAAGNFE LEILEISNTN
110 120 130 140 150
SHLLNGYCCG MPAELRATKT IGCSPCTTAF RLCLKEYQTT EQGASISTGC
160 170 180 190 200
SFGNATTKIL GGSSFVLSDP GVGAIVLPFT FRWTKSFTLI LQALDMYNTS
210 220 230 240 250
YPDAERLIEE TSYSGVILPS PEWKTLDHIG RNARITYRVR VQCAVTYYNT
260 270 280 290 300
TCTTFCRPRD DQFGHYACGS EGQKLCLNGW QGVNCEEAIC KAGCDPVHGK
310 320 330 340 350
CDRPGECECR PGWRGPLCNE CMVYPGCKHG SCNGSAWKCV CDTNWGGILC
360 370 380 390 400
DQDLNFCGTH EPCKHGGTCE NTAPDKYRCT CAEGLSGEQC EIVEHPCATR
410 420 430 440 450
PCRNGGTCTL KTSNRTQAQV YRTSHGRSNM GRPVRRSSSM RSLDHLRPEG
460 470 480 490 500
QALNASSSSG LVSLGSLQLQ QQLAPDFTCD CAAGWTGPTC EINIDECAGG
510 520 530 540 550
PCEHGGTCID LIGGFRCECP PEWHGDVCQV DVNECEAPHS AGIAANALLT
560 570 580 590 600
TTATAIIGSN LSSTALLAAL TSAVASTSMA IGPCINAKEC RNQPGSFACI
610 620 630 640 650
CKEGWGGVTC AENLDDCVGQ CRNGASCIDL VNDYRCACAA GFTGRDCETD
660 670 680 690 700
IDECATSPCR NGGECVDMVG KFNCICPLGY SGSLCEEAKE NCTPSPCLEG
710 720 730 740 750
HCLNTPEGYY CHCPPDRAGK HCEQLRPLCS QPPCNEGCFA NVSLATGLPC
760 770 780 790 800
SGHGSCEMSD VGTFCKCHVG HTGTFCEHNL NECSPNPCRN GGICLDGDGD
810 820 830 840 850
FTCECMSGWT GKRCSERATG CYAGQCQNGG TCMPGAPDKA LQPHCRCAPG
860 870 880 890 900
WTGLFCAEAI DQCRGQPCHN GGTCESGAGW FRCVCAQGFS GPDCRINVNE
910 920 930 940 950
CSPQPCQGGA TCIDGIGGYS CICPPGRHGL RCEILLSDPK SACQNASNTI
960 970 980 990 1000
SPYTALNRSQ NWLDIALTGR TEDDENCNAC VCENGTSRCT NLWCGLPNCY
1010 1020 1030 1040 1050
KVDPLSKSSN LSGVCKQHEV CVPALSETCL SSPCSVRGDC RALEPSRRVA
1060 1070 1080 1090 1100
PPRLPAKSSC WPNQAVVNEN CARLTILLAL ERVGKGASVE GLCSLVRVLL
1110 1120 1130 1140 1150
AAQLIKKPAS TFGQDPGMLM VLCDLKTGTN DTVELTVSSS KLNDPQLPVG
1160 1170 1180 1190 1200
VGLLGELLSS RQLTGIQRRK ELELQHAKLA ALTSIVEVKL ETARVADGSG
1210 1220 1230 1240 1250
HSLLIGVLCG VFIVLVGFSV FISLYWKQRL AYRTSSGMNL TPSLDALRHE
1260 1270 1280 1290 1300
EEKSNNLQNE ENLRRYTNPL KGSTSSLRAA TGMELSLNPA PELAASAASS
1310 1320 1330 1340 1350
SALHRSQPLF PPCDFERELD SSTGLKQAHK RSSQILLHKT QNSDMRKNTV
1360 1370 1380
GSLDSPRKDF GKRSINCKSM PPSSGDEGSD VLATTVMV
Length:1,388
Mass (Da):148,649
Last modified:September 23, 2008 - v1
Checksum:iFFE105A60E23C9A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000364 Genomic DNA. Translation: EDX14639.1.

Genome annotation databases

EnsemblMetazoaiFBtr0217999; FBpp0216491; FBgn0189632.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000364 Genomic DNA. Translation: EDX14639.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0217999; FBpp0216491; FBgn0189632.

Organism-specific databases

FlyBaseiFBgn0189632. Dsim\GD18089.

Phylogenomic databases

OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiB4QXF3.

Family and domain databases

InterProiIPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR011651. Notch_ligand_N.
IPR001007. VWF_dom.
[Graphical view]
PfamiPF01414. DSL. 1 hit.
PF00008. EGF. 6 hits.
PF07645. EGF_CA. 1 hit.
PF12661. hEGF. 2 hits.
PF07657. MNNL. 1 hit.
[Graphical view]
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiSM00051. DSL. 1 hit.
SM00181. EGF. 14 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 8 hits.
PS50026. EGF_3. 13 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4QXF3_DROSI
AccessioniPrimary (citable) accession number: B4QXF3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 30, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.