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Protein
Submitted name:

GD18123

Gene

Dsim\GD18123

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
GD18123Imported
Gene namesi
Name:Dsim\GD18123Imported
ORF Names:Dsim_GD18123Imported, GD18123Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000304 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0189665. Dsim\GD18123.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500282476522 – 654Sequence analysisAdd BLAST633

Expressioni

Gene expression databases

BgeeiFBgn0189665.

Structurei

3D structure databases

ProteinModelPortaliB4QWQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 122S8_pro-domainInterPro annotationAdd BLAST80
Domaini187 – 448Peptidase S8InterPro annotationAdd BLAST262
Domaini534 – 620P_proproteinInterPro annotationAdd BLAST87

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK01360.
OMAiPQRGVLK.
OrthoDBiEOG091G05HI.
PhylomeDBiB4QWQ8.

Family and domain databases

CDDicd04059. Peptidases_S8_Protein_converta. 1 hit.
Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiView protein in InterPro
IPR008979. Galactose-bd-like.
IPR034182. Kexin/furin.
IPR009020. Peptidase/Inhibitor_I9.
IPR000209. Peptidase_S8/S53_dom.
IPR036852. Peptidase_S8/S53_dom_sf.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR002884. PrprotnconvertsP.
IPR032815. S8_pro-domain.
PfamiView protein in Pfam
PF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF16470. S8_pro-domain. 1 hit.
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiView protein in PROSITE
PS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.

Sequencei

Sequence statusi: Complete.

B4QWQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAATWSWLL APFLLLHWAS AGAGGGAGGA GAGLSGPAVF TSSFLVRFRR
60 70 80 90 100
GVDNAFAHDV ADKYGFDNLG PLVGADGHEY HFKHRTLPHA RSRRSLTHTR
110 120 130 140 150
ALKSHPAVHT AVQQPGFKRV KRGLRPAVPA IHGMKFDLKV GEGNRIDEEP
160 170 180 190 200
TDPYFPMQWY LKNTGQNGGK VRLDLNVQAA WAQGITGKNV TTAIMDDGVD
210 220 230 240 250
YMHPDLKFNY NAEASYDFSS NDPFPYPRYT DDWFNSHGTR CAGEVAAARD
260 270 280 290 300
NGICGVGVAY DSKIAGIRML DQPYMTDLIE ANSMGHEPHK IHIYSASWGP
310 320 330 340 350
TDDGKTVDGP RNATMRAIVQ GVNEGRNGLG NIYVWASGDG GEEDDCNCDG
360 370 380 390 400
YAASMWTISI NSAINDGQNA HYDESCSSTL ASTFSNGAKD PNTGVATTDL
410 420 430 440 450
YGKCTTTHSG TSAAAPEAAG VFALALEANP QLTWRDIQHL TVLTSKRNSL
460 470 480 490 500
FDAKNRFHWT MNGVGLEFNH LFGFGVLDAG AMVTLSKQWH AVPPRYHCEA
510 520 530 540 550
GELTQPQAIV MGRSLFWEIK TDACKGTDTE VNYLEHVQAV ISANASRRGD
560 570 580 590 600
LELFLTSPMG TKSMILSRRA NDDDHRDGFT KWPFMTTHSW GEYPQGTWKL
610 620 630 640 650
EARFNSPQTR HGNLLEWSLV LHGTKEAPYR TLHPSSPHSK LAIVKKAHED

KKMK
Length:654
Mass (Da):71,685
Last modified:September 23, 2008 - v1
Checksum:i223EC7CA98B4B57A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000364 Genomic DNA. Translation: EDX14575.1.
RefSeqiXP_002105072.1. XM_002105036.2.

Genome annotation databases

EnsemblMetazoaiFBtr0218033; FBpp0216525; FBgn0189665.
GeneIDi6729766.
KEGGidsi:Dsimw501_GD18123.

Similar proteinsi

Entry informationi

Entry nameiB4QWQ8_DROSI
AccessioniPrimary (citable) accession number: B4QWQ8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 25, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported