B4QUN4 (B4QUN4_DROSI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GD18718 EMBL EDX13441.1

Gene names

Name:	Dsim\GD18718 EMBL EDX13441.1
ORF Names:	Dsim_GD18718 EMBL EDX13441.1, GD18718 FlyBase FBgn0190239

Organism

Drosophila simulans (Fruit fly) [Complete proteome] EMBL EDX13441.1

Taxonomic identifier

7240 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. RuleBase RU004542 SAAS SAAS007728 S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine.
Subcellular location	Nucleus By similarity RuleBase RU004542.
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 Contains 1 pre-SET domain. RuleBase RU004542 Contains SET domain. SAAS SAAS007728 Contains pre-SET domain. SAAS SAAS007728

Ontologies

Keywords
Cellular component	Chromosome SAAS SAAS007728 Nucleus RuleBase RU004542 SAAS SAAS007728
Ligand	S-adenosyl-L-methionine SAAS SAAS007728
Molecular function	Methyltransferase SAAS SAAS007728 RuleBase RU004542 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	peptidyl-lysine methylation Inferred from electronic annotation. Source: GOC
Cellular_component	chromosome Inferred from electronic annotation. Source: UniProtKB-KW nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4QUN4 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 63195121938146B8	FASTA	223	24,974
	10 20 30 40 50 60 MDESEPAPND DYEHPDGLEY ILESVLMPSD GSKEFKCLAD EYNSVLLNPC HCKGACENSE 70 80 90 100 110 120 VCPHGGQYEF TGDGSELILR NSANPVIECN DMCKCCRNTC SNRLVYSGPR KHLEIFDSPE 130 140 150 160 170 180 YGSKGLRTTV KIPKGGYICE YAGELLTVPE AKRRLHVNEK LGLMNYVLVL NEYTSDKKQQ 190 200 210 220 VTIVDPSRRG NIGRYLNHSC EPNCHIAAVR IDCPIPKIGK FYC

References

[1]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Mixed EMBL EDX13441.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000364 Genomic DNA. Translation: EDX13441.1.
RefSeq	XP_002103938.1. XM_002103902.1.
3D structure databases
ModBase	Search...
MobiDB	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0218628; FBpp0217120; FBgn0190239.
GeneID	6728597.
KEGG	dsi:Dsim_GD18718.
Organism-specific databases
FlyBase	FBgn0190239. Dsim\GD18718.
Phylogenomic databases
KO	K11433.
OrthoDB	EOG744T8D.
Family and domain databases
InterPro	IPR007728. Pre-SET_dom. IPR001214. SET_dom. [Graphical view]
Pfam	PF05033. Pre-SET. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS50867. PRE_SET. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B4QUN4_DROSI

Accession

Primary (citable) accession number: B4QUN4

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	February 19, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)