B4QSV9 (B4QSV9_DROSI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

Name:	GD20571 FlyBase FBgn0192039
Synonyms:	Dsim\GD20571 EMBL EDX13219.1
ORF Names:	Dsim_GD20571 EMBL EDX13219.1

Organism

Drosophila simulans (Fruit fly) [Complete proteome]

Taxonomic identifier

7240 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	362 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4QSV9 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 75D9993C9764B6FF	FASTA	362	40,952
	10 20 30 40 50 60 MASKGWHNED NKLDTFRRIC DEIAGESSYL KKAEKLQRFF EKGSSGKGFK GDTLLWVQFL 70 80 90 100 110 120 IPAANQRVYN LQNKALIKLF SRIFNADQQQ MHLDLEQDGD VSETLRKHFA ASKKLKPQAQ 130 140 150 160 170 180 SKLYLQEVEE MLLKLVERTK EDEQTDLLQK LCSKATDLDL RTFIRLVKHD LRINARARHI 190 200 210 220 230 240 LDAFGPDAYP TYQSSRDLVA IVGQFAGKEN KKDASSAVKK VKKTNSSGIQ VMTPISPMLA 250 260 270 280 290 300 SPCKSVEEAF KKSPTGLYSE IKYDGERVQI HKQGNDFKFF SRNLKPVVDH KIRDLKKYIP 310 320 330 340 350 360 LAFPGGGKMI LDSEIILVDT DTGALLPFGS LGAHKKHTFT NAAVCLFVFD CILYDGEDLT QL

References

[1]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Mixed EMBL EDX13219.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000364 Genomic DNA. Translation: EDX13219.1.
RefSeq	XP_002103716.1. XM_002103680.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0220481; FBpp0218973; FBgn0192039.
GeneID	6728368.
KEGG	dsi:Dsim_GD20571.
Organism-specific databases
FlyBase	FBgn0192039. Dsim\GD20571.
Phylogenomic databases
KO	K10776.
OrthoDB	EOG4BNZSZ.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit.
InterPro	IPR000977. DNA_ligase_ATP-dep. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. [Graphical view]
Pfam	PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SUPFAM	SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS00697. DNA_LIGASE_A1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B4QSV9_DROSI

Accession

Primary (citable) accession number: B4QSV9

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	March 6, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)