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Protein

DNA ligase

Gene

Dsim\GD20571

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dsim\GD20571Imported
ORF Names:Dsim_GD20571Imported, GD20571Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000304 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0192039. Dsim\GD20571.

Expressioni

Gene expression databases

BgeeiFBgn0192039.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 184DNA_ligase_A_NInterPro annotationAdd BLAST170
Domaini237 – 361DNA_LIGASE_A3InterPro annotationAdd BLAST125

Phylogenomic databases

OrthoDBiEOG091G0XBU.
PhylomeDBiB4QSV9.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
InterProiView protein in InterPro
IPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR036599. DNA_ligase_N_sf.
PfamiView protein in Pfam
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
SUPFAMiSSF117018. SSF117018. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiView protein in PROSITE
PS00697. DNA_LIGASE_A1. 1 hit.

Sequencei

Sequence statusi: Complete.

B4QSV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASKGWHNED NKLDTFRRIC DEIAGESSYL KKAEKLQRFF EKGSSGKGFK
60 70 80 90 100
GDTLLWVQFL IPAANQRVYN LQNKALIKLF SRIFNADQQQ MHLDLEQDGD
110 120 130 140 150
VSETLRKHFA ASKKLKPQAQ SKLYLQEVEE MLLKLVERTK EDEQTDLLQK
160 170 180 190 200
LCSKATDLDL RTFIRLVKHD LRINARARHI LDAFGPDAYP TYQSSRDLVA
210 220 230 240 250
IVGQFAGKEN KKDASSAVKK VKKTNSSGIQ VMTPISPMLA SPCKSVEEAF
260 270 280 290 300
KKSPTGLYSE IKYDGERVQI HKQGNDFKFF SRNLKPVVDH KIRDLKKYIP
310 320 330 340 350
LAFPGGGKMI LDSEIILVDT DTGALLPFGS LGAHKKHTFT NAAVCLFVFD
360
CILYDGEDLT QL
Length:362
Mass (Da):40,952
Last modified:September 23, 2008 - v1
Checksum:i75D9993C9764B6FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000364 Genomic DNA. Translation: EDX13219.1.

Genome annotation databases

EnsemblMetazoaiFBtr0220481; FBpp0218973; FBgn0192039.

Similar proteinsi

Entry informationi

Entry nameiB4QSV9_DROSI
AccessioniPrimary (citable) accession number: B4QSV9
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 25, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported