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B4QSV9

- B4QSV9_DROSI

UniProt

B4QSV9 - B4QSV9_DROSI

Protein

DNA ligase

Gene

Dsim\GD20571

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Name:Dsim\GD20571Imported
    ORF Names:Dsim_GD20571Imported, GD20571Imported
    OrganismiDrosophila simulans (Fruit fly)Imported
    Taxonomic identifieri7240 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000304: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0192039. Dsim\GD20571.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK10776.
    OrthoDBiEOG7BKCT2.
    PhylomeDBiB4QSV9.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    [Graphical view]
    PfamiPF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4QSV9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASKGWHNED NKLDTFRRIC DEIAGESSYL KKAEKLQRFF EKGSSGKGFK    50
    GDTLLWVQFL IPAANQRVYN LQNKALIKLF SRIFNADQQQ MHLDLEQDGD 100
    VSETLRKHFA ASKKLKPQAQ SKLYLQEVEE MLLKLVERTK EDEQTDLLQK 150
    LCSKATDLDL RTFIRLVKHD LRINARARHI LDAFGPDAYP TYQSSRDLVA 200
    IVGQFAGKEN KKDASSAVKK VKKTNSSGIQ VMTPISPMLA SPCKSVEEAF 250
    KKSPTGLYSE IKYDGERVQI HKQGNDFKFF SRNLKPVVDH KIRDLKKYIP 300
    LAFPGGGKMI LDSEIILVDT DTGALLPFGS LGAHKKHTFT NAAVCLFVFD 350
    CILYDGEDLT QL 362
    Length:362
    Mass (Da):40,952
    Last modified:September 23, 2008 - v1
    Checksum:i75D9993C9764B6FF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000364 Genomic DNA. Translation: EDX13219.1.
    RefSeqiXP_002103716.1. XM_002103680.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0220481; FBpp0218973; FBgn0192039.
    GeneIDi6728368.
    KEGGidsi:Dsim_GD20571.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000364 Genomic DNA. Translation: EDX13219.1 .
    RefSeqi XP_002103716.1. XM_002103680.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0220481 ; FBpp0218973 ; FBgn0192039 .
    GeneIDi 6728368.
    KEGGi dsi:Dsim_GD20571.

    Organism-specific databases

    FlyBasei FBgn0192039. Dsim\GD20571.

    Phylogenomic databases

    KOi K10776.
    OrthoDBi EOG7BKCT2.
    PhylomeDBi B4QSV9.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    [Graphical view ]
    Pfami PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MixedImported.

    Entry informationi

    Entry nameiB4QSV9_DROSI
    AccessioniPrimary (citable) accession number: B4QSV9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3