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B4QSV9

- B4QSV9_DROSI

UniProt

B4QSV9 - B4QSV9_DROSI

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Protein

DNA ligase

Gene

Dsim\GD20571

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dsim\GD20571Imported
ORF Names:Dsim_GD20571Imported, GD20571Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000304: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0192039. Dsim\GD20571.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10776.
OrthoDBiEOG7BKCT2.
PhylomeDBiB4QSV9.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
[Graphical view]
PfamiPF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4QSV9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASKGWHNED NKLDTFRRIC DEIAGESSYL KKAEKLQRFF EKGSSGKGFK
60 70 80 90 100
GDTLLWVQFL IPAANQRVYN LQNKALIKLF SRIFNADQQQ MHLDLEQDGD
110 120 130 140 150
VSETLRKHFA ASKKLKPQAQ SKLYLQEVEE MLLKLVERTK EDEQTDLLQK
160 170 180 190 200
LCSKATDLDL RTFIRLVKHD LRINARARHI LDAFGPDAYP TYQSSRDLVA
210 220 230 240 250
IVGQFAGKEN KKDASSAVKK VKKTNSSGIQ VMTPISPMLA SPCKSVEEAF
260 270 280 290 300
KKSPTGLYSE IKYDGERVQI HKQGNDFKFF SRNLKPVVDH KIRDLKKYIP
310 320 330 340 350
LAFPGGGKMI LDSEIILVDT DTGALLPFGS LGAHKKHTFT NAAVCLFVFD
360
CILYDGEDLT QL
Length:362
Mass (Da):40,952
Last modified:September 23, 2008 - v1
Checksum:i75D9993C9764B6FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000364 Genomic DNA. Translation: EDX13219.1.
RefSeqiXP_002103716.1. XM_002103680.1.

Genome annotation databases

EnsemblMetazoaiFBtr0220481; FBpp0218973; FBgn0192039.
GeneIDi6728368.
KEGGidsi:Dsim_GD20571.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000364 Genomic DNA. Translation: EDX13219.1 .
RefSeqi XP_002103716.1. XM_002103680.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0220481 ; FBpp0218973 ; FBgn0192039 .
GeneIDi 6728368.
KEGGi dsi:Dsim_GD20571.

Organism-specific databases

FlyBasei FBgn0192039. Dsim\GD20571.

Phylogenomic databases

KOi K10776.
OrthoDBi EOG7BKCT2.
PhylomeDBi B4QSV9.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
[Graphical view ]
Pfami PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MixedImported.

Entry informationi

Entry nameiB4QSV9_DROSI
AccessioniPrimary (citable) accession number: B4QSV9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3