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B4QK81

- B4QK81_DROSI

UniProt

B4QK81 - B4QK81_DROSI

Protein

Aldose 1-epimerase

Gene

Dsim\GD14983

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.UniRule annotation

    Catalytic activityi

    Alpha-D-glucose = beta-D-glucose.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. aldose 1-epimerase activity Source: UniProtKB-EC
    2. carbohydrate binding Source: InterPro

    GO - Biological processi

    1. hexose metabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotation

    Keywords - Biological processi

    Carbohydrate metabolismUniRule annotation

    Enzyme and pathway databases

    UniPathwayiUPA00242.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
    Alternative name(s):
    Galactose mutarotaseUniRule annotation
    Gene namesi
    Name:Dsim\GD14983Imported
    ORF Names:Dsim_GD14983Imported, GD14983Imported
    OrganismiDrosophila simulans (Fruit fly)Imported
    Taxonomic identifieri7240 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000304: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0186655. Dsim\GD14983.

    Structurei

    3D structure databases

    ProteinModelPortaliB4QK81.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldose epimerase family.UniRule annotation

    Phylogenomic databases

    KOiK01785.
    OrthoDBiEOG7V7666.
    PhylomeDBiB4QK81.

    Family and domain databases

    Gene3Di2.70.98.10. 1 hit.
    InterProiIPR015443. Aldose_1-epimerase.
    IPR008183. Aldose_1/G6P_1-epimerase.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    [Graphical view]
    PfamiPF01263. Aldose_epim. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005096. GALM. 1 hit.
    SUPFAMiSSF74650. SSF74650. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4QK81-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVRVIEDMFG IAVNPMTQKT DRVRRFTLIT ERGMSVSILT MGAIIQSLKV    50
    PDFNGKLEDV CLGYDDVAGY YRNQQYFFGA TIGRMANRTA HGRFKLCGKE 100
    VSVSRNLRDR HHQNGGFVGF DSVIWDVVGV HKDGVTLQHI SPDGHEGYPG 150
    ELTTNINFSL NETGCFGMRI EARTKATTAV NISNHSFFNL AGHGAGRDSL 200
    YQHMLMIKAQ KIVDVDQELL PTGKLMRVRT TPYDFSSLVS LGKRLNQVST 250
    CPLGGFDNHF CVDIPPNRVQ LVARVVHPCS GRFMEVHTNQ PGLQFSTANH 300
    LPSEDSSDIP ISGKDGSNYV RQGAFTLQTQ KYPDAMNHCD FPSVVLNPGQ 350
    LYDHQVVYRF GSCPKRV 367
    Length:367
    Mass (Da):40,876
    Last modified:September 23, 2008 - v1
    Checksum:i08C73D9935476E59
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000363 Genomic DNA. Translation: EDX11418.1.
    RefSeqiXP_002085833.1. XM_002085797.1.
    UniGeneiDsi.391.

    Genome annotation databases

    EnsemblMetazoaiFBtr0214893; FBpp0213385; FBgn0186655.
    GeneIDi6739038.
    KEGGidsi:Dsim_GD14983.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000363 Genomic DNA. Translation: EDX11418.1 .
    RefSeqi XP_002085833.1. XM_002085797.1.
    UniGenei Dsi.391.

    3D structure databases

    ProteinModelPortali B4QK81.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0214893 ; FBpp0213385 ; FBgn0186655 .
    GeneIDi 6739038.
    KEGGi dsi:Dsim_GD14983.

    Organism-specific databases

    FlyBasei FBgn0186655. Dsim\GD14983.

    Phylogenomic databases

    KOi K01785.
    OrthoDBi EOG7V7666.
    PhylomeDBi B4QK81.

    Enzyme and pathway databases

    UniPathwayi UPA00242 .

    Family and domain databases

    Gene3Di 2.70.98.10. 1 hit.
    InterProi IPR015443. Aldose_1-epimerase.
    IPR008183. Aldose_1/G6P_1-epimerase.
    IPR011013. Gal_mutarotase_SF_dom.
    IPR014718. Glyco_hydro-type_carb-bd_sub.
    [Graphical view ]
    Pfami PF01263. Aldose_epim. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005096. GALM. 1 hit.
    SUPFAMi SSF74650. SSF74650. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MixedImported.

    Entry informationi

    Entry nameiB4QK81_DROSI
    AccessioniPrimary (citable) accession number: B4QK81
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3