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Protein

Aldose 1-epimerase

Gene

Dsim\GD13155

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathway:ihexose metabolism

This protein is involved in the pathway hexose metabolism, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway hexose metabolism and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Name:Dsim\GD13155Imported
ORF Names:Dsim_GD13155Imported, GD13155Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000304 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0184877. Dsim\GD13155.

Structurei

3D structure databases

ProteinModelPortaliB4QJ93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

KOiK01785.
OrthoDBiEOG7V7666.
PhylomeDBiB4QJ93.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4QJ93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNITEDVFA NGAVNPLTKS KDTIKRFTLT NGAGMSVQLI TRGATITSIK
60 70 80 90 100
TPDASGQIDD VTLGFDDLAG YQSERNPYFG ATIGRICNRI ANGSFYLDGK
110 120 130 140 150
LVEVSKNRDN KFQLHGGFVG FDKAHWEVVE VRGDGVTLSH TNPDGHEGYP
160 170 180 190 200
GKVTATASFT LSEDNCLHVQ MSAVADQTTP VNLTNHSYFN LAGHKSGANG
210 220 230 240 250
LYEHTIEINA YGITETDQSS IPTGRITPVE GTGFDLRVSS NLGERLKALQ
260 270 280 290 300
PARGYDDNFC VTFSPPQPLA KVARATHPPS GRWLEVVSNQ PGVQFYTSNF
310 320 330 340 350
MPDVERGESP IPGKDGAAYA KHGAFCLETQ KFPDSVNHSN FPSTILRPGE
360
SYQHEVIYKF GVSH
Length:364
Mass (Da):39,520
Last modified:September 23, 2008 - v1
Checksum:i51554B3A4B0B0C91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000363 Genomic DNA. Translation: EDX09402.1.
RefSeqiXP_002083817.1. XM_002083781.1.
UniGeneiDsi.3677.

Genome annotation databases

EnsemblMetazoaiFBtr0213065; FBpp0211557; FBgn0184877.
GeneIDi6736970.
KEGGidsi:Dsim_GD13155.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000363 Genomic DNA. Translation: EDX09402.1.
RefSeqiXP_002083817.1. XM_002083781.1.
UniGeneiDsi.3677.

3D structure databases

ProteinModelPortaliB4QJ93.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0213065; FBpp0211557; FBgn0184877.
GeneIDi6736970.
KEGGidsi:Dsim_GD13155.

Organism-specific databases

FlyBaseiFBgn0184877. Dsim\GD13155.

Phylogenomic databases

KOiK01785.
OrthoDBiEOG7V7666.
PhylomeDBiB4QJ93.

Enzyme and pathway databases

UniPathwayiUPA00242.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MixedImported.

Entry informationi

Entry nameiB4QJ93_DROSI
AccessioniPrimary (citable) accession number: B4QJ93
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: February 4, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.