B4QJ93 (B4QJ93_DROSI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aldose 1-epimerase PIRNR PIRNR005096
EC=5.1.3.3 PIRNR PIRNR005096

Alternative name(s):
Galactose mutarotase PIRNR PIRNR005096

Gene names

Name:	GD13155 FlyBase FBgn0184877
Synonyms:	Dsim\GD13155 EMBL EDX09402.1
ORF Names:	Dsim_GD13155 EMBL EDX09402.1

Organism

Drosophila simulans (Fruit fly) [Complete proteome]

Taxonomic identifier

7240 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity. PIRNR PIRNR005096
Catalytic activity	Alpha-D-glucose = beta-D-glucose. PIRNR PIRNR005096
Pathway	Carbohydrate metabolism; hexose metabolism. PIRNR PIRNR005096
Sequence similarities	Belongs to the aldose epimerase family. PIRNR PIRNR005096

Ontologies

Keywords
Biological process	Carbohydrate metabolism PIRNR PIRNR005096
Molecular function	Isomerase PIRNR PIRNR005096
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	hexose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro isomerase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4QJ93 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 51554B3A4B0B0C91	FASTA	364	39,520
	10 20 30 40 50 60 MVNITEDVFA NGAVNPLTKS KDTIKRFTLT NGAGMSVQLI TRGATITSIK TPDASGQIDD 70 80 90 100 110 120 VTLGFDDLAG YQSERNPYFG ATIGRICNRI ANGSFYLDGK LVEVSKNRDN KFQLHGGFVG 130 140 150 160 170 180 FDKAHWEVVE VRGDGVTLSH TNPDGHEGYP GKVTATASFT LSEDNCLHVQ MSAVADQTTP 190 200 210 220 230 240 VNLTNHSYFN LAGHKSGANG LYEHTIEINA YGITETDQSS IPTGRITPVE GTGFDLRVSS 250 260 270 280 290 300 NLGERLKALQ PARGYDDNFC VTFSPPQPLA KVARATHPPS GRWLEVVSNQ PGVQFYTSNF 310 320 330 340 350 360 MPDVERGESP IPGKDGAAYA KHGAFCLETQ KFPDSVNHSN FPSTILRPGE SYQHEVIYKF GVSH

References

[1]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Mixed EMBL EDX09402.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000363 Genomic DNA. Translation: EDX09402.1.
RefSeq	XP_002083817.1. XM_002083781.1.
UniGene	Dsi.3677.
3D structure databases
ProteinModelPortal	B4QJ93.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0213065; FBpp0211557; FBgn0184877.
GeneID	6736970.
KEGG	dsi:Dsim_GD13155.
Organism-specific databases
FlyBase	FBgn0184877. Dsim\GD13155.
Phylogenomic databases
KO	K01785.
OrthoDB	EOG4QRFKS.
Enzyme and pathway databases
UniPathway	UPA00242.
Family and domain databases
Gene3D	2.70.98.10. 1 hit.
InterPro	IPR018052. Ald1_epimerase_CS. IPR015443. Aldose_1-epimerase. IPR008183. Aldose_1/G6P_1-epimerase. IPR011013. Gal_mutarotase_SF_dom. IPR014718. Glyco_hydro-type_carb-bd_sub. [Graphical view]
PANTHER	PTHR10091. PTHR10091. 1 hit.
Pfam	PF01263. Aldose_epim. 1 hit. [Graphical view]
PIRSF	PIRSF005096. GALM. 1 hit.
SUPFAM	SSF74650. Gal_mut_like. 1 hit.
PROSITE	PS00545. ALDOSE_1_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B4QJ93_DROSI

Accession

Primary (citable) accession number: B4QJ93

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)