Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Aldose 1-epimerase

Gene

Dsim\GD13155

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi: hexose metabolism

This protein is involved in the pathway hexose metabolism, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway hexose metabolism and in Carbohydrate metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei186Proton donorUniRule annotation1
Binding sitei256SubstrateUniRule annotation1
Active sitei328Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationImported
Biological processCarbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Name:Dsim\GD13155Imported
ORF Names:Dsim_GD13155Imported, Dsimw501_GD13155Imported, GD13155Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000304 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0184877. Dsim\GD13155.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiFBgn0184877.

Structurei

3D structure databases

ProteinModelPortaliB4QJ93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

KOiK01785.
OMAiLSSHTYW.
OrthoDBiEOG091G0COE.
PhylomeDBiB4QJ93.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiView protein in InterPro
IPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_sf_dom.
IPR014718. GH-type_carb-bd.
PfamiView protein in Pfam
PF01263. Aldose_epim. 1 hit.
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiView protein in PROSITE
PS00545. ALDOSE_1_EPIMERASE. 1 hit.

Sequencei

Sequence statusi: Complete.

B4QJ93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNITEDVFA NGAVNPLTKS KDTIKRFTLT NGAGMSVQLI TRGATITSIK
60 70 80 90 100
TPDASGQIDD VTLGFDDLAG YQSERNPYFG ATIGRICNRI ANGSFYLDGK
110 120 130 140 150
LVEVSKNRDN KFQLHGGFVG FDKAHWEVVE VRGDGVTLSH TNPDGHEGYP
160 170 180 190 200
GKVTATASFT LSEDNCLHVQ MSAVADQTTP VNLTNHSYFN LAGHKSGANG
210 220 230 240 250
LYEHTIEINA YGITETDQSS IPTGRITPVE GTGFDLRVSS NLGERLKALQ
260 270 280 290 300
PARGYDDNFC VTFSPPQPLA KVARATHPPS GRWLEVVSNQ PGVQFYTSNF
310 320 330 340 350
MPDVERGESP IPGKDGAAYA KHGAFCLETQ KFPDSVNHSN FPSTILRPGE
360
SYQHEVIYKF GVSH
Length:364
Mass (Da):39,520
Last modified:September 23, 2008 - v1
Checksum:i51554B3A4B0B0C91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000363 Genomic DNA. Translation: EDX09402.1.
CM002912 Genomic DNA. Translation: KMY97861.1.
RefSeqiXP_002083817.1. XM_002083781.2.

Genome annotation databases

EnsemblMetazoaiFBtr0213065; FBpp0211557; FBgn0184877.
GeneIDi6736970.
KEGGidsi:Dsimw501_GD13155.

Similar proteinsi

Entry informationi

Entry nameiB4QJ93_DROSI
AccessioniPrimary (citable) accession number: B4QJ93
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 22, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported