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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

Dsim\GD25078

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei97NADUniRule annotation1
Binding sitei120SubstrateUniRule annotation1
Binding sitei154NAD; via amide nitrogenUniRule annotation1
Binding sitei269NADUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Name:Dsim\GD25078Imported
ORF Names:Dsim_GD25078Imported, Dsimw501_GD25078Imported, GD25078Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000304 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0196390 Dsim\GD25078

Subcellular locationi

Expressioni

Gene expression databases

BgeeiFBgn0196390

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 173NAD_Gly3P_dh_NInterPro annotationAdd BLAST168
Domaini194 – 339NAD_Gly3P_dh_CInterPro annotationAdd BLAST146

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni269 – 270Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

KOiK00006
OMAiADCVEIC
OrthoDBiEOG091G0DO6

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR017751 G3P_DH_NAD-dep_euk
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR03376 glycerol3P_DH, 1 hit

Sequencei

Sequence statusi: Complete.

B4QI65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKIMICIIG SGNWATTIAR NVGRNVLNSQ TLDEKVPMYV YEEIVEGRKL
60 70 80 90 100
TEIINTTHVN SKYMPNFELP PNIVAVDDIV TTARDADIII FAIPPTFVSS
110 120 130 140 150
CCKTLLGKVK PTAHAVSLIK GFERGDDGQF VLISQIIMRQ LKIPCSVLVG
160 170 180 190 200
CNLAHELAHD HFAEGTVGCR DQKYYRVLHD IFKSPTFRVV VTEDADCVEI
210 220 230 240 250
CSTLRNIIAF AAGCSDGMEL NENTKGGIIR RGFLEMLQFV DVFYPGCRMG
260 270 280 290 300
TFFESCGISD LVTSCYANRN RKLAEAFVKT GKPLSELEHI LIPGHEPLGP
310 320 330 340 350
VTAELVHHML KKKGLEDKFP LFTTVYRICT GDYPLQRLVE TLIKAREDIF

HPLHTFQL
Length:358
Mass (Da):40,070
Last modified:September 23, 2008 - v1
Checksum:i67B8ED47EB930FD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000362 Genomic DNA Translation: EDX08319.1
CM002911 Genomic DNA Translation: KMY95971.1
RefSeqiXP_002082734.1, XM_002082698.2

Genome annotation databases

EnsemblMetazoaiFBtr0224988; FBpp0223480; FBgn0196390
GeneIDi6735824
KEGGidsi:Dsimw501_GD25078

Similar proteinsi

Entry informationi

Entry nameiB4QI65_DROSI
AccessioniPrimary (citable) accession number: B4QI65
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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