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Protein

Angiotensin-converting enzyme

Gene

Dsim\GD10112

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Dsim\GD10112Imported
ORF Names:Dsim_GD10112Imported, Dsimw501_GD10112Imported, GD10112Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000304 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0181887. Dsim\GD10112.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500764226918 – 608Angiotensin-converting enzymeSequence analysisAdd BLAST591

Keywords - PTMi

GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0181887.

Structurei

3D structure databases

ProteinModelPortaliB4QGQ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK01283.
OMAiGAKMPNE.
OrthoDBiEOG091G0345.
PhylomeDBiB4QGQ4.

Family and domain databases

InterProiView protein in InterPro
IPR001548. Peptidase_M2.
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiView protein in Pfam
PF01401. Peptidase_M2. 1 hit.
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

B4QGQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLLLLVLIA GIGCATAAAN IDLEAKTFVN QSSDRYYRFY NEIAAETYSA
60 70 80 90 100
NNEEDFDALF SKLNNVKRIA EELVSISRQA ATYDLDRIRS PQTKLALQEL
110 120 130 140 150
RTAGDLFVLG DDYFSSVQMN LAALQTLSTD KDIEPYLGGA NMPNEDDSPL
160 170 180 190 200
AYFPDIQKIV QSSKDADELK YYWEAWRDKN QLWASLNFYT IVQSYQRAAK
210 220 230 240 250
ILEVPVHKLW YRYDSQEMLQ QMEQAMTELR PAYQQLHAFV RQELHKKYGS
260 270 280 290 300
DVVSLNGPIP DHLFQQVLEQ AWASGSILED YYPRAQLPEF DEYVSHLTAK
310 320 330 340 350
AMVNESENFY TSLGFEPLSA EFHKNQLKEP NQDSPNDDCR PSIFDLTPHV
360 370 380 390 400
YLMYCEKVSF RKLMQYHSHM ARVYYAQQKS HLPSYYFKAY NLEFAVGEAV
410 420 430 440 450
VLSASSPAHL TGRRLAKEVL SETALMSRLF RMAIHTILSI PLYYVHTKVM
460 470 480 490 500
HDLLNDTVDM DTVNKHYWRL MEQHAGIEAP SDRSEGAIDF PYKFYVNIDQ
510 520 530 540 550
SFQTQKFISE VLGYQFYREF CKKSFNRGPL HNCDFYGSLA VGNDLKSMMS
560 570 580 590 600
LGSTKPWKQV VGKILPNNTG LSSLALLEYY QPVLGWLNKY NKDANSKIGW

TASKKKIV
Length:608
Mass (Da):69,911
Last modified:September 23, 2008 - v1
Checksum:i0FB3B1A429497AD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000362 Genomic DNA. Translation: EDX06279.1.
CM002911 Genomic DNA. Translation: KMY92406.1.
RefSeqiXP_002080694.1. XM_002080658.2.

Genome annotation databases

EnsemblMetazoaiFBtr0210022; FBpp0208514; FBgn0181887.
GeneIDi6733640.
KEGGidsi:Dsimw501_GD10112.

Similar proteinsi

Entry informationi

Entry nameiB4QGQ4_DROSI
AccessioniPrimary (citable) accession number: B4QGQ4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: August 30, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported