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Protein

Angiotensin-converting enzyme

Gene

Dsim\GD24910

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Dsim\GD24910Imported
ORF Names:Dsim_GD24910Imported, Dsimw501_GD24910Imported, GD24910Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000304 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0196226. Dsim\GD24910.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500764211920 – 628Angiotensin-converting enzymeSequence analysisAdd BLAST609

Keywords - PTMi

GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0196226.

Structurei

3D structure databases

ProteinModelPortaliB4QCL9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK01283.
OMAiDYNCAYW.
OrthoDBiEOG091G02N8.
PhylomeDBiB4QCL9.

Family and domain databases

InterProiView protein in InterPro
IPR001548. Peptidase_M2.
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiView protein in Pfam
PF01401. Peptidase_M2. 1 hit.
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

B4QCL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLPFVGVLL ILLLSVTFGI GHSSYELATK QILDRAKDRM RHVWSLNRRI
60 70 80 90 100
FVQLTAKGKS PLGGQVLNSK LEVEAETYRL FYDLAGNLSV VSVAELDDPL
110 120 130 140 150
LRRRVQRMAK LQLQGLRPKD YEQAKDLLRQ IHNFVNGPLV CPYEDCSARG
160 170 180 190 200
SLAMYPQIMN KNMHTKLYED LVINWKAWRR AINEKDVAKN TFIGYVRLLR
210 220 230 240 250
IAATYNGHVT PSRTWYLNYD TENFQAEMEA VVWEIMPLYR ELHAYLRREV
260 270 280 290 300
QAAYPKADTK SDGAISAPIM DQILSQDWYP HQFFRTPHQG RQHQLPSVHR
310 320 330 340 350
RLEEVLVTPV KINRKAAEFF ESLGLMVMPN IFYDRFSRRM NDEEGGAECK
360 370 380 390 400
SQVYYFPPDV ALRYCPKLDY KKMMQIHGTM AELQYHLYKM QLPFGLDTEP
410 420 430 440 450
CPGFGAAIAE TVILASGTPR HLHRLHILLN DSLTEEQSLN RLFRMGVHTL
460 470 480 490 500
IAVPQYFIND KFLVDVMDGR IGVKDYNCAY WGLQDKFAGV QPPLQRLNKD
510 520 530 540 550
FDVDFKFYRG LNPETSNTKK FLAEILGFQF YRSFCLASGQ YKPGDPNFPL
560 570 580 590 600
HNCDFYDSKE AGKKIRDMMQ LGATRHWRDV MEIATGERKL SGRGILEYFA
610 620
PLFTWLKERN KQLDIEPGWD ADELCRRD
Length:628
Mass (Da):72,943
Last modified:September 23, 2008 - v1
Checksum:iD51D35A3061FB630
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000362 Genomic DNA. Translation: EDX08635.1.
CM002911 Genomic DNA. Translation: KMY96457.1.
RefSeqiXP_002083050.1. XM_002083014.2.

Genome annotation databases

EnsemblMetazoaiFBtr0224820; FBpp0223312; FBgn0196226.
GeneIDi6736150.
KEGGidsi:Dsimw501_GD24910.

Similar proteinsi

Entry informationi

Entry nameiB4QCL9_DROSI
AccessioniPrimary (citable) accession number: B4QCL9
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: August 30, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported