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B4QB17

- B4QB17_DROSI

UniProt

B4QB17 - B4QB17_DROSI

Protein

DNA ligase

Gene

Dsim\GD11806

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Name:Dsim\GD11806Imported
    ORF Names:Dsim_GD11806Imported, GD11806Imported
    OrganismiDrosophila simulans (Fruit fly)Imported
    Taxonomic identifieri7240 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000304: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0183545. Dsim\GD11806.

    Structurei

    3D structure databases

    ProteinModelPortaliB4QB17.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    KOiK10747.
    OrthoDBiEOG7RFTGN.
    PhylomeDBiB4QB17.

    Family and domain databases

    Gene3Di1.10.3260.10. 2 hits.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4QB17-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQKSITSFFK KKSDATDSPS PPKKVPKIDA KTELPDEPHI KSESASPETK    50
    PKVEPMSVDS EEKTSPVKNV KKEPKDTVDK TTDKKVTTIG LNSTSASKED 100
    AENYDPSADS YHPLKNAYWK DKKVTPYLAL ARTFQVIEET KGRLKMIDTL 150
    SNFFCSVMLV SPEDLVPSVY LSINQLAPAY EGMELGVAET TLMKAICKAT 200
    GRNLAHIKSQ THLIGDLGIV AEQSRVSQRM MFQPAPLNVR DVFRKLREIA 250
    KISGQSKMDM VYNMFVACRL SEARFFIRSL IGKLRIGMQS RVCSQRWPLG 300
    CQCPNYDIII PAILKYDIKE LQERCPMHPG MPLRPMLAQP TKGVHEVFER 350
    FGGMQITCEW KYDGERAQIH RNEKGEISIF SRNSENNTAK YPDLIARSTG 400
    LLKGDVKSYI IDSEIVAWDV ERKQILPFQV LSTRKRKNVD IEEIKVQVCV 450
    YIFDLLYING TALVTKNLSE RRKLLLEHFQ EVEGEWKFAT ALDTNDIDEV 500
    QQFLEESIKG NCEGLMVKTL DEEATYEIAK RSRNWLKLKK DYLSNVGDSL 550
    DLVVIGGYKG KGRRTGTYGG FLLACYDTEN EEYQSICKIG TGFTDEDLQT 600
    HSEFLGKHVT SAAKSYYRYD PSLEPDHWFE PVQVWEVKCA DLSLSPIHRA 650
    AIGIVDGERG ISLRFPRFIR IRDDKNSENA TDANQVAHMY QSQDQVKNNQ 700
    KSSTQMEMED EFY 713
    Length:713
    Mass (Da):81,123
    Last modified:September 23, 2008 - v1
    Checksum:i3EAA7852A2B47DAD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000362 Genomic DNA. Translation: EDX08454.1.
    RefSeqiXP_002082869.1. XM_002082833.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0211716; FBpp0210208; FBgn0183545.
    GeneIDi6735960.
    KEGGidsi:Dsim_GD11806.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000362 Genomic DNA. Translation: EDX08454.1 .
    RefSeqi XP_002082869.1. XM_002082833.1.

    3D structure databases

    ProteinModelPortali B4QB17.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0211716 ; FBpp0210208 ; FBgn0183545 .
    GeneIDi 6735960.
    KEGGi dsi:Dsim_GD11806.

    Organism-specific databases

    FlyBasei FBgn0183545. Dsim\GD11806.

    Phylogenomic databases

    KOi K10747.
    OrthoDBi EOG7RFTGN.
    PhylomeDBi B4QB17.

    Family and domain databases

    Gene3Di 1.10.3260.10. 2 hits.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MixedImported.

    Entry informationi

    Entry nameiB4QB17_DROSI
    AccessioniPrimary (citable) accession number: B4QB17
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3