UniProtKB - B4Q7L0 (B4Q7L0_DROSI)
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Protein
Aspartate aminotransferase
Gene
Dsim\GD22881
Organism
Drosophila simulans (Fruit fly)
Status
Functioni
Miscellaneous
In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.UniRule annotation
Catalytic activityi
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.UniRule annotation
GO - Molecular functioni
- L-aspartate:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
- L-phenylalanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
- pyridoxal phosphate binding Source: InterPro
GO - Biological processi
- biosynthetic process Source: InterPro
- cellular amino acid metabolic process Source: InterPro
Keywordsi
Molecular function | AminotransferaseUniRule annotationImported, Transferase |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:Dsim\GD22881Imported ORF Names:Dsim_GD22881Imported, Dsimw501_GD22881Imported, GD22881Imported |
Organismi | Drosophila simulans (Fruit fly)Imported |
Taxonomic identifieri | 7240 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0194275. Dsim\GD22881. |
Interactioni
Subunit structurei
Homodimer.UniRule annotation
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 52 – 419 | Aminotran_1_2InterPro annotationAdd BLAST | 368 |
Phylogenomic databases
KOi | K14455. |
OMAi | RVGACTI. |
OrthoDBi | EOG091G06G3. |
PhylomeDBi | B4Q7L0. |
Family and domain databases
Gene3Di | 3.40.640.10. 1 hit. 3.90.1150.10. 2 hits. |
InterProi | View protein in InterPro IPR004839. Aminotransferase_I/II. IPR000796. Asp_trans. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase. IPR015422. PyrdxlP-dep_Trfase_dom1. IPR015421. PyrdxlP-dep_Trfase_major. |
PANTHERi | PTHR11879. PTHR11879. 1 hit. |
Pfami | View protein in Pfam PF00155. Aminotran_1_2. 1 hit. |
PRINTSi | PR00799. TRANSAMINASE. |
SUPFAMi | SSF53383. SSF53383. 1 hit. |
PROSITEi | View protein in PROSITE PS00105. AA_TRANSFER_CLASS_1. 1 hit. |
i Sequence
Sequence statusi: Complete.
B4Q7L0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSQICKRGLL ISNRLAPAAL RCKSTWFSEV QMGPPDAILG VTEAFKKDTN
60 70 80 90 100
PKKINLGAGA YRDDNTQPFV LPSVREAEKR VLSRNLDKEY ATIIGIPEFY
110 120 130 140 150
NKAIELALGK GSKRLAAKHN VTAQSISGTG ALRIGAAFLA KFWKGNREIY
160 170 180 190 200
IPSPSWGNHV PIFEHAGLPV NRYRYYDKDT CALDFGGLIE DLKKIPEKSI
210 220 230 240 250
VLLHACAHNP TGVDPSLEQW REISALVKKR NLYPFIDMAY QGFATGDIDR
260 270 280 290 300
DAQAVRTFEA DGHDFCLAQS FAKNMGLYGE RAGAFTVVCS DEEEAARVMS
310 320 330 340 350
QVKILIRGLY SNPPVHGARI AAEILNNEDL RAQWLKDVKL MADRIIDVRA
360 370 380 390 400
QLKNNLIKLG SSQNWDHIVN QIGMFCFTGL KPEQVQKLIK DHSVYLTNDG
410 420
RVSMAGVTSK NVEYLAESIH KVTK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM000361 Genomic DNA. Translation: EDX03390.1. CM002910 Genomic DNA. Translation: KMY87557.1. |
RefSeqi | XP_002077805.1. XM_002077769.2. |
Genome annotation databases
EnsemblMetazoai | FBtr0222791; FBpp0221283; FBgn0194275. |
GeneIDi | 6730628. |
KEGGi | dsi:Dsimw501_GD22881. |
Similar proteinsi
Entry informationi
Entry namei | B4Q7L0_DROSI | |
Accessioni | B4Q7L0Primary (citable) accession number: B4Q7L0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | February 28, 2018 | |
This is version 60 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |