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Protein

Aspartate aminotransferase

Gene

Dsim\GD22881

Organism
Drosophila simulans (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferaseUniRule annotation (EC:2.6.1.1UniRule annotation)
Gene namesi
Name:Dsim\GD22881Imported
ORF Names:Dsim_GD22881Imported, Dsimw501_GD22881Imported, GD22881Imported
OrganismiDrosophila simulans (Fruit fly)Imported
Taxonomic identifieri7240 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000304 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0194275. Dsim\GD22881.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB4Q7L0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 419Aminotran_1_2InterPro annotationAdd BLAST368

Phylogenomic databases

KOiK14455.
OMAiWANHAAV.
OrthoDBiEOG091G06G3.
PhylomeDBiB4Q7L0.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4Q7L0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQICKRGLL ISNRLAPAAL RCKSTWFSEV QMGPPDAILG VTEAFKKDTN
60 70 80 90 100
PKKINLGAGA YRDDNTQPFV LPSVREAEKR VLSRNLDKEY ATIIGIPEFY
110 120 130 140 150
NKAIELALGK GSKRLAAKHN VTAQSISGTG ALRIGAAFLA KFWKGNREIY
160 170 180 190 200
IPSPSWGNHV PIFEHAGLPV NRYRYYDKDT CALDFGGLIE DLKKIPEKSI
210 220 230 240 250
VLLHACAHNP TGVDPSLEQW REISALVKKR NLYPFIDMAY QGFATGDIDR
260 270 280 290 300
DAQAVRTFEA DGHDFCLAQS FAKNMGLYGE RAGAFTVVCS DEEEAARVMS
310 320 330 340 350
QVKILIRGLY SNPPVHGARI AAEILNNEDL RAQWLKDVKL MADRIIDVRA
360 370 380 390 400
QLKNNLIKLG SSQNWDHIVN QIGMFCFTGL KPEQVQKLIK DHSVYLTNDG
410 420
RVSMAGVTSK NVEYLAESIH KVTK
Length:424
Mass (Da):47,193
Last modified:September 23, 2008 - v1
Checksum:iB0B60220D1DD350D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000361 Genomic DNA. Translation: EDX03390.1.
CM002910 Genomic DNA. Translation: KMY87557.1.
RefSeqiXP_002077805.1. XM_002077769.2.

Genome annotation databases

EnsemblMetazoaiFBtr0222791; FBpp0221283; FBgn0194275.
GeneIDi6730628.
KEGGidsi:Dsimw501_GD22881.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000361 Genomic DNA. Translation: EDX03390.1.
CM002910 Genomic DNA. Translation: KMY87557.1.
RefSeqiXP_002077805.1. XM_002077769.2.

3D structure databases

ProteinModelPortaliB4Q7L0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0222791; FBpp0221283; FBgn0194275.
GeneIDi6730628.
KEGGidsi:Dsimw501_GD22881.

Organism-specific databases

FlyBaseiFBgn0194275. Dsim\GD22881.

Phylogenomic databases

KOiK14455.
OMAiWANHAAV.
OrthoDBiEOG091G06G3.
PhylomeDBiB4Q7L0.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4Q7L0_DROSI
AccessioniPrimary (citable) accession number: B4Q7L0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 2, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.