Dsim\GD22881

Functionⁱ

Catalytic activityⁱ

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.UniRule annotation

GO - Molecular functionⁱ

L-aspartate:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
L-phenylalanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
pyridoxal phosphate binding Source: InterPro

GO - Biological processⁱ

biosynthetic process Source: InterPro
cellular amino acid metabolic process Source: InterPro

Complete GO annotation...

Keywords - Molecular functionⁱ

AminotransferaseUniRule annotationImported, Transferase

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Aspartate aminotransferaseUniRule annotation Automatic assertion according to rulesⁱ RuleBase:RU000480 (EC:2.6.1.1UniRule annotation Automatic assertion according to rulesⁱ RuleBase:RU000480 )
Gene namesⁱ	Name:Dsim\GD22881Imported Automatic assertion inferred from database entriesⁱ EMBL:EDX03390.1 ORF Names:Dsim_GD22881Imported Automatic assertion inferred from database entriesⁱ EMBL:EDX03390.1 , Dsimw501_GD22881Imported Automatic assertion inferred from database entriesⁱ EMBL:KMY87557.1 , GD22881Imported Automatic assertion inferred from database entriesⁱ FlyBase:FBgn0194275
Organismⁱ	Drosophila simulans (Fruit fly)Imported Automatic assertion inferred from database entriesⁱ EMBL:EDX03390.1 Proteomes:UP000000304
Taxonomic identifierⁱ	7240 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophila › Sophophora › melanogaster group › melanogaster subgroup
Proteomesⁱ	UP000000304 Componentⁱ: Chromosome 2L

Organism-specific databases

FlyBaseⁱ	FBgn0194275. Dsim\GD22881.

FlyBaseⁱ

FBgn0194275. Dsim\GD22881.

Interactionⁱ

Subunit structureⁱ

Homodimer.UniRule annotation

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Domainⁱ	52 – 419	368	Aminotran_1_2InterPro annotation Automatic assertion inferred from signature matchⁱ Pfam:PF00155			Add BLAST

Phylogenomic databases

KOⁱ	K14455.
OMAⁱ	WANHAAV.
OrthoDBⁱ	EOG091G06G3.
PhylomeDBⁱ	B4Q7L0.

Family and domain databases

Gene3Dⁱ	3.40.640.10. 1 hit.
InterProⁱ	IPR004839. Aminotransferase_I/II. IPR000796. Asp_trans. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHERⁱ	PTHR11879. PTHR11879. 1 hit.
Pfamⁱ	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
PRINTSⁱ	PR00799. TRANSAMINASE.
SUPFAMⁱ	SSF53383. SSF53383. 1 hit.
PROSITEⁱ	PS00105. AA_TRANSFER_CLASS_1. 1 hit. [Graphical view]

Sequenceⁱ

Sequence statusⁱ: Complete.

B4Q7L0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSQICKRGLL ISNRLAPAAL RCKSTWFSEV QMGPPDAILG VTEAFKKDTN 
        60         70         80         90        100
PKKINLGAGA YRDDNTQPFV LPSVREAEKR VLSRNLDKEY ATIIGIPEFY 
       110        120        130        140        150
NKAIELALGK GSKRLAAKHN VTAQSISGTG ALRIGAAFLA KFWKGNREIY 
       160        170        180        190        200
IPSPSWGNHV PIFEHAGLPV NRYRYYDKDT CALDFGGLIE DLKKIPEKSI 
       210        220        230        240        250
VLLHACAHNP TGVDPSLEQW REISALVKKR NLYPFIDMAY QGFATGDIDR 
       260        270        280        290        300
DAQAVRTFEA DGHDFCLAQS FAKNMGLYGE RAGAFTVVCS DEEEAARVMS 
       310        320        330        340        350
QVKILIRGLY SNPPVHGARI AAEILNNEDL RAQWLKDVKL MADRIIDVRA 
       360        370        380        390        400
QLKNNLIKLG SSQNWDHIVN QIGMFCFTGL KPEQVQKLIK DHSVYLTNDG 
       410        420 
RVSMAGVTSK NVEYLAESIH KVTK

Length:424

Mass (Da):47,193

Last modified:September 23, 2008 - v1

Checksum:ⁱB0B60220D1DD350D

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CM000361 Genomic DNA. Translation: EDX03390.1. CM002910 Genomic DNA. Translation: KMY87557.1.
RefSeqⁱ	XP_002077805.1. XM_002077769.2.

Genome annotation databases

EnsemblMetazoaⁱ	FBtr0222791; FBpp0221283; FBgn0194275.
GeneIDⁱ	6730628.
KEGGⁱ	dsi:Dsim_GD22881.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CM000361 Genomic DNA. Translation: EDX03390.1. CM002910 Genomic DNA. Translation: KMY87557.1.
RefSeqⁱ	XP_002077805.1. XM_002077769.2.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblMetazoaⁱ	FBtr0222791; FBpp0221283; FBgn0194275.
GeneIDⁱ	6730628.
KEGGⁱ	dsi:Dsim_GD22881.

Organism-specific databases

FlyBaseⁱ	FBgn0194275. Dsim\GD22881.

FlyBaseⁱ

FBgn0194275. Dsim\GD22881.

Phylogenomic databases

KOⁱ	K14455.
OMAⁱ	WANHAAV.
OrthoDBⁱ	EOG091G06G3.
PhylomeDBⁱ	B4Q7L0.

Family and domain databases

Gene3Dⁱ	3.40.640.10. 1 hit.
InterProⁱ	IPR004839. Aminotransferase_I/II. IPR000796. Asp_trans. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHERⁱ	PTHR11879. PTHR11879. 1 hit.
Pfamⁱ	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
PRINTSⁱ	PR00799. TRANSAMINASE.
SUPFAMⁱ	SSF53383. SSF53383. 1 hit.
PROSITEⁱ	PS00105. AA_TRANSFER_CLASS_1. 1 hit. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

B4Q7L0_DROSI

Accessionⁱ

Primary (citable) accession number: B4Q7L0

Entry historyⁱ

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	September 7, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.UniRule annotation

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB - B4Q7L0 (B4Q7L0_DROSI)

UniProt

B4Q7L0 - B4Q7L0_DROSI

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Aspartate aminotransferase

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Functionⁱ

Catalytic activityⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywords - Molecular functionⁱ

Names & Taxonomyⁱ

Organism-specific databases

Interactionⁱ

Subunit structureⁱ

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Miscellaneous

Keywords - Technical termⁱ

Similar proteinsⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - B4Q7L0 (B4Q7L0_DROSI)

UniProt

B4Q7L0 - B4Q7L0_DROSI

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Aspartate aminotransferase

Dsim\GD22881

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Miscellaneous

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Interactionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ