Dsim\GD22881

Functionⁱ

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.UniRule annotation

Catalytic activityⁱ

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.UniRule annotation

GO - Molecular functionⁱ

L-aspartate:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
L-phenylalanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
pyridoxal phosphate binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

glutamate biosynthetic process Source: EnsemblMetazoa
neurotransmitter receptor metabolic process Source: EnsemblMetazoa
synapse assembly Source: EnsemblMetazoa

Complete GO annotation...

Keywordsⁱ

Molecular function	AminotransferaseUniRule annotationImported, Transferase

Molecular function

AminotransferaseUniRule annotationImported, Transferase

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Aspartate aminotransferaseUniRule annotation (EC:2.6.1.1UniRule annotation)
Gene namesⁱ	Name:Dsim\GD22881Imported ORF Names:Dsim_GD22881Imported, Dsimw501_GD22881Imported, GD22881Imported
Organismⁱ	Drosophila simulans (Fruit fly)Imported
Taxonomic identifierⁱ	7240 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophila › Sophophora › melanogaster group › melanogaster subgroup
Proteomesⁱ	UP000000304 Componentⁱ: Chromosome 2L

Organism-specific databases

Drosophila genome database More...FlyBaseⁱ	FBgn0194275. Dsim\GD22881.

FlyBaseⁱ

FBgn0194275. Dsim\GD22881.

Subcellular locationⁱ

GO - Cellular componentⁱ

mitochondrion Source: EnsemblMetazoa

Complete GO annotation...

Expressionⁱ

Gene expression databases

Bgeeⁱ	FBgn0194275.

Bgeeⁱ

FBgn0194275.

Interactionⁱ

Subunit structureⁱ

Homodimer.UniRule annotation

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	B4Q7L0.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	52 – 419	Aminotran_1_2InterPro annotationAdd BLAST		368

Phylogenomic databases

KEGG Orthology (KO) More...KOⁱ	K14455.
OMAⁱ	RVGACTI.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G06G3.
PhylomeDBⁱ	B4Q7L0.

Family and domain databases

Gene3Dⁱ	3.90.1150.10. 2 hits.
InterProⁱ	View protein in InterPro IPR004839. Aminotransferase_I/II. IPR000796. Asp_trans. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase. IPR015422. PyrdxlP-dep_Trfase_sub2.
PANTHERⁱ	PTHR11879. PTHR11879. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00155. Aminotran_1_2. 1 hit.
PRINTSⁱ	PR00799. TRANSAMINASE.
SUPFAMⁱ	SSF53383. SSF53383. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00105. AA_TRANSFER_CLASS_1. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

B4Q7L0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSQICKRGLL ISNRLAPAAL RCKSTWFSEV QMGPPDAILG VTEAFKKDTN 
        60         70         80         90        100
PKKINLGAGA YRDDNTQPFV LPSVREAEKR VLSRNLDKEY ATIIGIPEFY 
       110        120        130        140        150
NKAIELALGK GSKRLAAKHN VTAQSISGTG ALRIGAAFLA KFWKGNREIY 
       160        170        180        190        200
IPSPSWGNHV PIFEHAGLPV NRYRYYDKDT CALDFGGLIE DLKKIPEKSI 
       210        220        230        240        250
VLLHACAHNP TGVDPSLEQW REISALVKKR NLYPFIDMAY QGFATGDIDR 
       260        270        280        290        300
DAQAVRTFEA DGHDFCLAQS FAKNMGLYGE RAGAFTVVCS DEEEAARVMS 
       310        320        330        340        350
QVKILIRGLY SNPPVHGARI AAEILNNEDL RAQWLKDVKL MADRIIDVRA 
       360        370        380        390        400
QLKNNLIKLG SSQNWDHIVN QIGMFCFTGL KPEQVQKLIK DHSVYLTNDG 
       410        420 
RVSMAGVTSK NVEYLAESIH KVTK

Length:424

Mass (Da):47,193

Last modified:September 23, 2008 - v1

Checksum:ⁱB0B60220D1DD350D

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CM000361 Genomic DNA. Translation: EDX03390.1. CM002910 Genomic DNA. Translation: KMY87557.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_002077805.1. XM_002077769.2.

Genome annotation databases

EnsemblMetazoaⁱ	FBtr0222791; FBpp0221283; FBgn0194275.
GeneIDⁱ	6730628.
KEGGⁱ	dsi:Dsimw501_GD22881.

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
B4Q7L0	Q8IPY3 UPI0007E6AA8F E4NKM3 UPI0007E754A9 UPI0007E6A142 UPI0007E86DFA A0A0J9QTY9 A0A1W4V176 UPI0007E36BCC A0A0R1DQA5 +16	Drosophila melanogaster (Fruit fly) Drosophila takahashii (Fruit fly) Drosophila biarmipes (Fruit fly) Drosophila eugracilis (Fruit fly) Drosophila rhopaloa (Fruit fly) Drosophila simulans (Fruit fly) Drosophila ficusphila (Fruit fly) Drosophila suzukii (Spotted-wing drosophila fruit fly) Drosophila yakuba (Fruit fly) Drosophila erecta (Fruit fly) And more	431	UniRef90_Q8IPY3	Cluster: Aspartate aminotransferase	27

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
B4Q7L0	P46643 Q56YR4 UPI00085A6181 A0A178VP87 UPI0004F15F75 UPI0006AAF18F D7LCW9 UPI000945218C R0HCH5 A0A078E984 +141	Arabidopsis thaliana (Mouse-ear cress) Raphanus sativus (Radish) Brassica campestris (Field mustard) Brassica napus (Rape) Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress) Rhinolophus sinicus (Chinese rufous horseshoe bat) Capsella rubella Brassica oleracea var. oleracea Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum) Noccaea caerulescens (Alpine penny-cress) (Thlaspi caerulescens) And more	430	UniRef50_P46643	Cluster: Aspartate aminotransferase, mitochondrial	152

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CM000361 Genomic DNA. Translation: EDX03390.1. CM002910 Genomic DNA. Translation: KMY87557.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_002077805.1. XM_002077769.2.

3D structure databases

ProteinModelPortalⁱ	B4Q7L0.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblMetazoaⁱ	FBtr0222791; FBpp0221283; FBgn0194275.
GeneIDⁱ	6730628.
KEGGⁱ	dsi:Dsimw501_GD22881.

Organism-specific databases

Drosophila genome database More...FlyBaseⁱ	FBgn0194275. Dsim\GD22881.

FlyBaseⁱ

FBgn0194275. Dsim\GD22881.

Phylogenomic databases

KEGG Orthology (KO) More...KOⁱ	K14455.
OMAⁱ	RVGACTI.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G06G3.
PhylomeDBⁱ	B4Q7L0.

Gene expression databases

Bgeeⁱ	FBgn0194275.

Bgeeⁱ

FBgn0194275.

Family and domain databases

Gene3Dⁱ	3.90.1150.10. 2 hits.
InterProⁱ	View protein in InterPro IPR004839. Aminotransferase_I/II. IPR000796. Asp_trans. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase. IPR015422. PyrdxlP-dep_Trfase_sub2.
PANTHERⁱ	PTHR11879. PTHR11879. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00155. Aminotran_1_2. 1 hit.
PRINTSⁱ	PR00799. TRANSAMINASE.
SUPFAMⁱ	SSF53383. SSF53383. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00105. AA_TRANSFER_CLASS_1. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B4Q7L0_DROSI
Accessionⁱ	B4Q7L0Primary (citable) accession number: B4Q7L0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	September 23, 2008
	Last sequence update:	September 23, 2008
	Last modified:	August 30, 2017
	This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - B4Q7L0 (B4Q7L0_DROSI)

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Aspartate aminotransferase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ