B4Q2B7 (B4Q2B7_DROYA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GE17076 EMBL EDX01578.1

Gene names

Name:	Dyak\GE17076 EMBL EDX01578.1
ORF Names:	Dyak_GE17076 EMBL EDX01578.1, GE17076 FlyBase FBgn0234559

Organism

Drosophila yakuba (Fruit fly) [Complete proteome]

Taxonomic identifier

7245 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	2397 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 Contains 1 post-SET domain. RuleBase RU004541 SAAS SAAS001214

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS001214
Molecular function	Methyltransferase RuleBase RU004541 SAAS SAAS001214 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular_component	chromosome Inferred from electronic annotation. Source: InterPro nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4Q2B7 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 0371CECB4367A7E4	FASTA	2,397	265,016
	10 20 30 40 50 60 MEESGLPSNP SAVASRGRGR GRPPKVAPPA MAALKNADAE ASPTPAEDQD SGQSECRRSS 70 80 90 100 110 120 RKKIIKFDVR DLLNKNRKAH KIQIEARIDS NPSPGQSAGT TGATTSATIA SAASAASGNS 130 140 150 160 170 180 AASVSRLFSM FEMSHQSLPP PPPPPALEIF AKPRPTQSLI VAQVTSEPSA VGGGHPVQPM 190 200 210 220 230 240 ANQPAVTPRK RGRPRKSQPA EVAIVPTVIA PSCSDSDTNS TSTTTSNMSS DSGELPGFPK 250 260 270 280 290 300 RKPKSKLRVS LKRLNLSRRQ ASSDSGNSPS SSSPEVEPPA LQDENALDEQ PDQEQNLSGM 310 320 330 340 350 360 VVAEETSDSD SQIIFIEIET ESPKGQEEQE EQEEERPVEV EPQELIDIDI ELAKQGPTPD 370 380 390 400 410 420 PEQDLDEIMV EVLSGPPSLW SADDEAEEEE DVTVQRATPP ENEPAADSSS PAPRRSRRSA 430 440 450 460 470 480 PLSGSSRQGK TLEETFAEIA AESSKQILEA EESQDQEEQH ILIDLIEDTL SEPEVTSSVS 490 500 510 520 530 540 PIIEHTELAE EIVVEDNPLD VVLESKPDLV TETSSVASKA EQAFSESDIN AATVKEVIPE 550 560 570 580 590 600 PKVATKATRN EELASAVVPK PELVTVERSS IAQGIAETME QLHEQPTKPT KPPTETIIAE 610 620 630 640 650 660 TKPTLEVAKE TPPKDEAAAK PAEEDQPASQ TAETIPDSER IPPIEVKAKA APPVLFVHDT 670 680 690 700 710 720 RDRAIGEAHD DQTSLSAVEK SNTKGEITEF LPTEITARKI EADRSLVAPA EDTSNEPKSR 730 740 750 760 770 780 EDSESNQEQS KAAVLEMKEH KKAPMPEMKE RKKPLAETAS KREKELEKPA RSSPAAGAKK 790 800 810 820 830 840 ERVAEREKEV VKSTKESVTP AKQKETAKAA KEAAAKKEAE KEKSSAKDDA SLALDELDKS 850 860 870 880 890 900 SVDFTPKKDK NTAPCPPLLP ILERSSTKPQ QESAQSEISK TTSNEAAGSA PKEDAPKEEL 910 920 930 940 950 960 AAKKPLADNA TTTVASTKAK EKLAAGFVEC DAMFKAMDKA NAQMRLEEKS KKKLKKVPPK 970 980 990 1000 1010 1020 VEAPSPVPMP SAAMPVPGHK KSLASKASSR RNTVYEDSPK QDRHSSPSSD SAQANTTASS 1030 1040 1050 1060 1070 1080 KLKRSKAKKK LNPRRSTICE EAKDLRASTS STPTEEVAAS SPVSTSSDSS SKRNAAKRTS 1090 1100 1110 1120 1130 1140 STEQLPGGSK LDQRRNTICE DRQADTAIPV PLTKRRFSMH PKASANPLHD TLLRTSGRKR 1150 1160 1170 1180 1190 1200 GRKGGKESLS RQSSLDSSSS ASQGATKKKA QKSADALNAA LLETESSEST SSGSKMRRWD 1210 1220 1230 1240 1250 1260 VQTSPELEAT NPLSDIAKFI EDGVNLLKRD YKVEEDQREE GQDEVKREAN TEEDEFAQRV 1270 1280 1290 1300 1310 1320 ANMETPATTP SPSPTQSNPE DSASTTTILQ ESNTGGGVRR SHRIKQKPQG QRASQGRGVA 1330 1340 1350 1360 1370 1380 SMALAPISMD EQLAELANIE AINEQFLRSE GLNTFQLLKE NYYRCARQVS QENAEMQCDC 1390 1400 1410 1420 1430 1440 FLTGDEEAQG HLSCGAGCIN RMLMIECGPL CTNGARCTNK RFQQHQCWPC RVFRTEKKGC 1450 1460 1470 1480 1490 1500 GITAELQIPP GEFIMEYVGE VIDSEEFERR QHLYSKDRNR HYYFMALRGE AIIDATSKGN 1510 1520 1530 1540 1550 1560 ISRYINHSCD PNAETQKWTV NGELRIGFFS VKPIQPGEEI TFDYQYQRYG RDAQRCYCEA 1570 1580 1590 1600 1610 1620 ANCRGWIGGE PDSDEGEQLD VDTDSDAELD EEELEAEPEA EEGQSRKTSA KAAKAKAKLK 1630 1640 1650 1660 1670 1680 AKLPLASSRK RKEQPKPKDR EYKAGRWLKP SAGGPSSAEK ASRKPKVNKF HAMLEDPDVL 1690 1700 1710 1720 1730 1740 EELSLLSRSG LKNQLDTLRF SRCMVRAKLL HTRLQLLGVL TRGELPCRRL FLDYHGLRLL 1750 1760 1770 1780 1790 1800 HAWISENGND DQLRVALLDT LESLPIPNRT MLNDSRVYQS VQLWSNSLEQ QQATVAHASQ 1810 1820 1830 1840 1850 1860 AALHKRMVAL LQKWQALPEI FRIPKRERIE QMKEHEREAD RQQKHVHAST ALEDQRERES 1870 1880 1890 1900 1910 1920 SNDRFRQDRF RRDTTSSRIS KPIRMSGNNT ICTITTQQKG SNGAMDGMAR SDNRRRSDMG 1930 1940 1950 1960 1970 1980 PSTEPRRTLS KELRRSLFER KVALDEAERR VCSEDWREHE LRCEFFGADL NTDPKQLPFY 1990 2000 2010 2020 2030 2040 QNADTGEWFN SDDMPVPAPP RTELLSQALL SPEMDGGQAV PAVEYKLPAG VDPLPPAWHW 2050 2060 2070 2080 2090 2100 RMTSDGDIYY YNLRERISQW EPPSPEQRLQ TLLEEDTTQQ PLHELQIDPA LLANELIQVD 2110 2120 2130 2140 2150 2160 MDYVGSLSSK SLAQYVEAKV RERRELRRSR LVSIRLISPR RDEDRLYNQL ESRKYKENKE 2170 2180 2190 2200 2210 2220 KIRRRKELYR RRKLDAPPDA SANAEDALPG KPLTIQAYLY SSDEEATEAP AAELTAGAAE 2230 2240 2250 2260 2270 2280 GTVAPDEEQE SLNLAPSTSH AALAALGKSV AQAMQPSAVG AAAKRKLPMP PSVSVKKHRQ 2290 2300 2310 2320 2330 2340 EQRSKKGTGG QSLLTTTSGR EAHEKFRFEI SGHVADFLRP YRKESCQLGR ITSDEDYKFL 2350 2360 2370 2380 2390 IKRLSHHITT KEVRYCDLTG NPLSCTESVK HKSYDFINQY MRKKGRVYRK PAESTIF

References

[1]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tai18E2 / Tucson 14021-0261.01.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000162 Genomic DNA. Translation: EDX01578.1.
RefSeq	XP_002100470.1. XM_002100434.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0263594; FBpp0262086; FBgn0234559.
GeneID	6524613.
KEGG	dya:Dyak_GE17076.
Organism-specific databases
FlyBase	FBgn0234559. Dyak\GE17076.
Phylogenomic databases
eggNOG	COG2940.
KO	K11423.
OrthoDB	EOG4THT7X.
Family and domain databases
InterPro	IPR017956. AT_hook_DNA-bd_motif. IPR006560. AWS. IPR003616. Post-SET_dom. IPR001214. SET_dom. IPR013257. SRI. IPR001202. WW_dom. [Graphical view]
Pfam	PF00856. SET. 1 hit. PF08236. SRI. 1 hit. PF00397. WW. 1 hit. [Graphical view]
SMART	SM00384. AT_hook. 2 hits. SM00570. AWS. 1 hit. SM00508. PostSET. 1 hit. SM00317. SET. 1 hit. SM00456. WW. 1 hit. [Graphical view]
SUPFAM	SSF51045. WW_Rsp5_WWP. 1 hit.
PROSITE	PS51215. AWS. 1 hit. PS50868. POST_SET. 1 hit. PS50280. SET. 1 hit. PS01159. WW_DOMAIN_1. 1 hit. PS50020. WW_DOMAIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B4Q2B7_DROYA

Accession

Primary (citable) accession number: B4Q2B7

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 29, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)