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Protein

Delta-like protein

Gene

Dyak\GE10581

Organism
Drosophila yakuba (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Putative Notch ligand involved in the mediation of Notch signaling.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Delta-like proteinUniRule annotation
Gene namesi
Name:Dyak\GE10581Imported
ORF Names:Dyak_GE10581Imported, GE10581Imported
OrganismiDrosophila yakuba (Fruit fly)Imported
Taxonomic identifieri7245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000002282 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0228436. Dyak\GE10581.

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1223 – 124624HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7245.FBpp0255591.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini238 – 28245DSLInterPro annotationAdd
BLAST
Domaini283 – 31634EGF-likeInterPro annotationAdd
BLAST
Domaini350 – 38839EGF-likeInterPro annotationAdd
BLAST
Domaini451 – 48838EGF-likeInterPro annotationAdd
BLAST
Domaini490 – 52637EGF-likeInterPro annotationAdd
BLAST
Domaini570 – 60839EGF-likeInterPro annotationAdd
BLAST
Domaini610 – 64536EGF-likeInterPro annotationAdd
BLAST
Domaini647 – 68337EGF-likeInterPro annotationAdd
BLAST
Domaini685 – 72036EGF-likeInterPro annotationAdd
BLAST
Domaini761 – 79737EGF-likeInterPro annotationAdd
BLAST
Domaini799 – 83537EGF-likeInterPro annotationAdd
BLAST
Domaini837 – 87741EGF-likeInterPro annotationAdd
BLAST
Domaini879 – 91537EGF-likeInterPro annotationAdd
BLAST
Domaini917 – 95337EGF-likeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 DSL domain.UniRule annotation
Contains 14 EGF-like domains.UniRule annotation

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation, SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1217. Eukaryota.
ENOG410XP6K. LUCA.
KOiK06052.
OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiB4PRU0.

Family and domain databases

InterProiIPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR011651. Notch_ligand_N.
IPR001007. VWF_dom.
[Graphical view]
PfamiPF01414. DSL. 1 hit.
PF00008. EGF. 6 hits.
PF07645. EGF_CA. 1 hit.
PF12661. hEGF. 2 hits.
PF07657. MNNL. 1 hit.
[Graphical view]
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiSM00051. DSL. 1 hit.
SM00181. EGF. 14 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 8 hits.
PS50026. EGF_3. 13 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4PRU0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKMFRKHFR RKPTTSSSTE STIESPDSLG MTKKTATKRQ RPRHREPKIA
60 70 80 90 100
TLPSTIRDCR SLKSACNLIA LILILLVHKI SAAGNFELEI LEISNTNSHL
110 120 130 140 150
LNGYCCGMPA ELRATKTIGC SPCTTAFRLC LKEYQTTEQG ASISTGCSFG
160 170 180 190 200
NATTKILGGS SFVLSDPGVG AIVLPFTFRW TKSFTLILQA LDMYNTSYPD
210 220 230 240 250
AERLIEETSY SGVILPSPEW KTLDHIGRNA RITYRVRVQC AVTYYNTTCT
260 270 280 290 300
TFCRPRDDQF GHYACGSEGQ KLCLNGWQGV NCEEAICKAG CDPVHGKCDR
310 320 330 340 350
PGECECRPGW RGPLCNECMV YPGCKHGSCN GSAWKCVCDT NWGGILCDQD
360 370 380 390 400
LNFCGTHEPC KHGGTCENTA PDKYRCTCAE GLSGEQCEIV EHPCATRPCR
410 420 430 440 450
NGGTCTLKTS NRTQAQVYRT SHGRGNMGRA VRRSSSMRSL DHLRLEGQAQ
460 470 480 490 500
NGSSSSGLVS LGSLQLQQQL APDFTCDCAA GWTGPTCEIN IDECAGGPCE
510 520 530 540 550
HGGTCIDLIG GFRCECPPEW HGDVCQVDVN ECEAPHSAGI AANALLTTTA
560 570 580 590 600
TAIIGSNLSS TALLAALTSA VASTSMAIGP CINAKECRNQ PGSFACICKE
610 620 630 640 650
GWGGVTCAEN LDDCVGQCRN GATCIDLVND YRCACAAGFT GRDCETDIDE
660 670 680 690 700
CATSPCRNGG ECVDMVGKFN CICPLGYSGS LCEEAKENCT PSPCLEGHCL
710 720 730 740 750
NTPEGYYCHC PPDRAGKHCE QLRPLCSQPP CNEGCFANVS LATSATTTST
760 770 780 790 800
TTTTSATTTR KMAKPNGLPC SGHGSCEMSD VGTFCKCHVG HTGTFCEHNL
810 820 830 840 850
NECSPNPCRN GGICLDGDGD FTCECMSGWT GKRCSERATG CYAGQCQNGG
860 870 880 890 900
TCMPGAPDKA LQPHCRCAPG WTGLFCAEAI DQCRGQPCHN GGTCESGAGW
910 920 930 940 950
FRCVCAQGFS GPDCRINVNE CSPQPCQGGA TCIDGIGGYS CICPPGRHGL
960 970 980 990 1000
RCEILLSDPK SACQNASNTI SPYTALNQSQ NWLDIALTGR SEDDENCNAC
1010 1020 1030 1040 1050
VCENGTSRCT NLWCGLPNCY KVDPLSKSSN LSGVCKQHEV CVPALSETCL
1060 1070 1080 1090 1100
SSPCTVRGDC RALEPSRRVA PPRLPAKSSC WPNQAVVNEN CARLTILLAL
1110 1120 1130 1140 1150
ERVGKGASVE GLCSLVRVLL AAQLIKKPAS TFGQDPGMLM VLCDLKTGTN
1160 1170 1180 1190 1200
DTVELTVSSS KINDQQLPVA VGLLGELLSS RQLNGIQRRK ELELQHAKLA
1210 1220 1230 1240 1250
ALTSIVEVKL ETARVADGSG HSLLIGVLCG VFIVLVGFSV FISLYWKQRL
1260 1270 1280 1290 1300
AYRTSSGMNL TPSLDALRHE EEKSNNLQNE ENLRRYTNPL KGSTSSLRAA
1310 1320 1330 1340 1350
TGMELSLNPA PELAASAASS SALHRSQPLF PPCDFERELD SSTGLKQAHK
1360 1370 1380 1390 1400
RSSQILLHKT QNSDMRKNTV GSLDSPRKDF GKRSINCKSM PPSSGDEGSD

VLATTVMV
Length:1,408
Mass (Da):150,810
Last modified:September 23, 2008 - v1
Checksum:i3C2726C10660EE0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000160 Genomic DNA. Translation: EDW98533.1.
RefSeqiXP_002098821.1. XM_002098785.2.

Genome annotation databases

EnsemblMetazoaiFBtr0257099; FBpp0255591; FBgn0228436.
GeneIDi6538294.
KEGGidya:Dyak_GE10581.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000160 Genomic DNA. Translation: EDW98533.1.
RefSeqiXP_002098821.1. XM_002098785.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7245.FBpp0255591.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0257099; FBpp0255591; FBgn0228436.
GeneIDi6538294.
KEGGidya:Dyak_GE10581.

Organism-specific databases

FlyBaseiFBgn0228436. Dyak\GE10581.

Phylogenomic databases

eggNOGiKOG1217. Eukaryota.
ENOG410XP6K. LUCA.
KOiK06052.
OMAiMPGAPDK.
OrthoDBiEOG091G0A88.
PhylomeDBiB4PRU0.

Family and domain databases

InterProiIPR001774. DSL.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR026219. Jagged/Serrate.
IPR011651. Notch_ligand_N.
IPR001007. VWF_dom.
[Graphical view]
PfamiPF01414. DSL. 1 hit.
PF00008. EGF. 6 hits.
PF07645. EGF_CA. 1 hit.
PF12661. hEGF. 2 hits.
PF07657. MNNL. 1 hit.
[Graphical view]
PRINTSiPR02059. JAGGEDFAMILY.
SMARTiSM00051. DSL. 1 hit.
SM00181. EGF. 14 hits.
SM00179. EGF_CA. 9 hits.
SM00215. VWC_out. 1 hit.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 7 hits.
PS51051. DSL. 1 hit.
PS00022. EGF_1. 14 hits.
PS01186. EGF_2. 8 hits.
PS50026. EGF_3. 13 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4PRU0_DROYA
AccessioniPrimary (citable) accession number: B4PRU0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: September 7, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.