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B4PIY6

- B4PIY6_DROYA

UniProt

B4PIY6 - B4PIY6_DROYA

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Protein

Catalase

Gene

Dyak\GE19975

Organism
Drosophila yakuba (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.UniRule annotation

Catalytic activityi

2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

Note: Heme group.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei73 – 731UniRule annotation
Active sitei146 – 1461UniRule annotation
Metal bindingi356 – 3561Iron (heme axial ligand)UniRule annotation

GO - Molecular functioni

  1. catalase activity Source: UniProtKB-EC
  2. heme binding Source: InterPro
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. hydrogen peroxide catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxideUniRule annotation

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
CatalaseUniRule annotation (EC:1.11.1.6UniRule annotation)
Gene namesi
Name:Dyak\GE19975Imported
ORF Names:Dyak_GE19975Imported, GE19975Imported
OrganismiDrosophila yakuba (Fruit fly)Imported
Taxonomic identifieri7245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000002282: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0237302. Dyak\GE19975.

Interactioni

Protein-protein interaction databases

STRINGi7245.FBpp0264985.

Family & Domainsi

Sequence similaritiesi

Belongs to the catalase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0753.
KOiK03781.
OrthoDBiEOG7V7660.
PhylomeDBiB4PIY6.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4PIY6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAGRDAASNQ LIDYKNSQTV SPGAITTGNG APIGIKDATQ TVGPRGPILL
60 70 80 90 100
QDVNFLDEMS HFDRERIPER VVHAKGAGAF GYFEVTHDIT QYCAAKVFDK
110 120 130 140 150
VKKRTPLAVR FSTVGGESGS ADTARDPRGF AVKFYTEDGV WDLVGNNTPI
160 170 180 190 200
FFIRDPILFP SFIHTQKRNP QTHLKDPDMF WDFLTLRPES AHQVCFLFGD
210 220 230 240 250
RGTPDGYCHM NGYGSHTFKL INAKGEPIYA KFHLKTDQGI KNLDVKTADQ
260 270 280 290 300
LASSDPDYSI RDLYNRIKTC KFPSWTMYIQ VMTFEQAKKF KYNPFDITKV
310 320 330 340 350
WSHKEYPLIP VGKMVLDRNP KNYFAEVEQI AFSPAHLVPG IEPSPDKMLQ
360 370 380 390 400
GRLFSYSDTH RHRLGPNYLQ IPVNCPYKVK IENFQRDGPM NVTDNQDGAP
410 420 430 440 450
NYFPNSFNGP QECPRARALS SCCPVTGDVY RYSSGDTEDN FGQVTDFWVH
460 470 480 490 500
VLDKCAKKRL VQNIAGHLSG ASQFLQERAV KNFTQVHADF GRMLTEELNL

AKSSKF
Length:506
Mass (Da):57,101
Last modified:September 23, 2008 - v1
Checksum:iCBEAA41E5D17DE82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000159 Genomic DNA. Translation: EDW94577.1.
RefSeqiXP_002094865.1. XM_002094829.1.

Genome annotation databases

EnsemblMetazoaiFBtr0266493; FBpp0264985; FBgn0237302.
GeneIDi6534182.
KEGGidya:Dyak_GE19975.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000159 Genomic DNA. Translation: EDW94577.1 .
RefSeqi XP_002094865.1. XM_002094829.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7245.FBpp0264985.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0266493 ; FBpp0264985 ; FBgn0237302 .
GeneIDi 6534182.
KEGGi dya:Dyak_GE19975.

Organism-specific databases

FlyBasei FBgn0237302. Dyak\GE19975.

Phylogenomic databases

eggNOGi COG0753.
KOi K03781.
OrthoDBi EOG7V7660.
PhylomeDBi B4PIY6.

Family and domain databases

Gene3Di 2.40.180.10. 1 hit.
InterProi IPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view ]
PANTHERi PTHR11465. PTHR11465. 1 hit.
Pfami PF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view ]
PIRSFi PIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSi PR00067. CATALASE.
SMARTi SM01060. Catalase. 1 hit.
[Graphical view ]
SUPFAMi SSF56634. SSF56634. 1 hit.
PROSITEi PS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tai18E2 / Tucson 14021-0261.01Imported.
  2. "Principles of genome evolution in the Drosophila melanogaster species group."
    Ranz J.M., Maurin D., Chan Y.S., von Grotthuss M., Hillier L.W., Roote J., Ashburner M., Bergman C.M.
    PLoS Biol. 5:E152-E152(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiB4PIY6_DROYA
AccessioniPrimary (citable) accession number: B4PIY6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 26, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3