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B4PIY6

- B4PIY6_DROYA

UniProt

B4PIY6 - B4PIY6_DROYA

Protein

Catalase

Gene

Dyak\GE19975

Organism
Drosophila yakuba (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.UniRule annotation

    Catalytic activityi

    2 H2O2 = O2 + 2 H2O.UniRule annotation

    Cofactori

    Heme group.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei73 – 731UniRule annotation
    Active sitei73 – 731 By similarity
    Active sitei146 – 1461UniRule annotation
    Metal bindingi356 – 3561Iron (heme axial ligand)UniRule annotation

    GO - Molecular functioni

    1. catalase activity Source: UniProtKB-EC
    2. heme binding Source: InterPro
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. hydrogen peroxide catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase, Peroxidase

    Keywords - Biological processi

    Hydrogen peroxideUniRule annotation

    Keywords - Ligandi

    HemeUniRule annotation, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    CatalaseUniRule annotation (EC:1.11.1.6UniRule annotation)
    Gene namesi
    Name:Dyak\GE19975Imported
    ORF Names:Dyak_GE19975Imported, GE19975Imported
    OrganismiDrosophila yakuba (Fruit fly)Imported
    Taxonomic identifieri7245 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000002282: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0237302. Dyak\GE19975.

    Interactioni

    Protein-protein interaction databases

    STRINGi7245.FBpp0264985.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the catalase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0753.
    KOiK03781.
    OrthoDBiEOG7V7660.
    PhylomeDBiB4PIY6.

    Family and domain databases

    Gene3Di2.40.180.10. 1 hit.
    InterProiIPR018028. Catalase.
    IPR020835. Catalase-like_dom.
    IPR024708. Catalase_AS.
    IPR024711. Catalase_clade1/3.
    IPR011614. Catalase_core.
    IPR002226. Catalase_haem_BS.
    IPR010582. Catalase_immune_responsive.
    [Graphical view]
    PANTHERiPTHR11465. PTHR11465. 1 hit.
    PfamiPF00199. Catalase. 1 hit.
    PF06628. Catalase-rel. 1 hit.
    [Graphical view]
    PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
    PRINTSiPR00067. CATALASE.
    SMARTiSM01060. Catalase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56634. SSF56634. 1 hit.
    PROSITEiPS00437. CATALASE_1. 1 hit.
    PS00438. CATALASE_2. 1 hit.
    PS51402. CATALASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4PIY6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGRDAASNQ LIDYKNSQTV SPGAITTGNG APIGIKDATQ TVGPRGPILL    50
    QDVNFLDEMS HFDRERIPER VVHAKGAGAF GYFEVTHDIT QYCAAKVFDK 100
    VKKRTPLAVR FSTVGGESGS ADTARDPRGF AVKFYTEDGV WDLVGNNTPI 150
    FFIRDPILFP SFIHTQKRNP QTHLKDPDMF WDFLTLRPES AHQVCFLFGD 200
    RGTPDGYCHM NGYGSHTFKL INAKGEPIYA KFHLKTDQGI KNLDVKTADQ 250
    LASSDPDYSI RDLYNRIKTC KFPSWTMYIQ VMTFEQAKKF KYNPFDITKV 300
    WSHKEYPLIP VGKMVLDRNP KNYFAEVEQI AFSPAHLVPG IEPSPDKMLQ 350
    GRLFSYSDTH RHRLGPNYLQ IPVNCPYKVK IENFQRDGPM NVTDNQDGAP 400
    NYFPNSFNGP QECPRARALS SCCPVTGDVY RYSSGDTEDN FGQVTDFWVH 450
    VLDKCAKKRL VQNIAGHLSG ASQFLQERAV KNFTQVHADF GRMLTEELNL 500
    AKSSKF 506
    Length:506
    Mass (Da):57,101
    Last modified:September 23, 2008 - v1
    Checksum:iCBEAA41E5D17DE82
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000159 Genomic DNA. Translation: EDW94577.1.
    RefSeqiXP_002094865.1. XM_002094829.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0266493; FBpp0264985; FBgn0237302.
    GeneIDi6534182.
    KEGGidya:Dyak_GE19975.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000159 Genomic DNA. Translation: EDW94577.1 .
    RefSeqi XP_002094865.1. XM_002094829.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7245.FBpp0264985.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0266493 ; FBpp0264985 ; FBgn0237302 .
    GeneIDi 6534182.
    KEGGi dya:Dyak_GE19975.

    Organism-specific databases

    FlyBasei FBgn0237302. Dyak\GE19975.

    Phylogenomic databases

    eggNOGi COG0753.
    KOi K03781.
    OrthoDBi EOG7V7660.
    PhylomeDBi B4PIY6.

    Family and domain databases

    Gene3Di 2.40.180.10. 1 hit.
    InterProi IPR018028. Catalase.
    IPR020835. Catalase-like_dom.
    IPR024708. Catalase_AS.
    IPR024711. Catalase_clade1/3.
    IPR011614. Catalase_core.
    IPR002226. Catalase_haem_BS.
    IPR010582. Catalase_immune_responsive.
    [Graphical view ]
    PANTHERi PTHR11465. PTHR11465. 1 hit.
    Pfami PF00199. Catalase. 1 hit.
    PF06628. Catalase-rel. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF038928. Catalase_clade1-3. 1 hit.
    PRINTSi PR00067. CATALASE.
    SMARTi SM01060. Catalase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56634. SSF56634. 1 hit.
    PROSITEi PS00437. CATALASE_1. 1 hit.
    PS00438. CATALASE_2. 1 hit.
    PS51402. CATALASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tai18E2 / Tucson 14021-0261.01Imported.
    2. "Principles of genome evolution in the Drosophila melanogaster species group."
      Ranz J.M., Maurin D., Chan Y.S., von Grotthuss M., Hillier L.W., Roote J., Ashburner M., Bergman C.M.
      PLoS Biol. 5:E152-E152(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiB4PIY6_DROYA
    AccessioniPrimary (citable) accession number: B4PIY6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3