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B4PA92

- B4PA92_DROYA

UniProt

B4PA92 - B4PA92_DROYA

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Protein
DNA ligase
Gene
Dyak\GE14336, Dyak_GE14336, GE14336
Organism
Drosophila yakuba (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:Dyak\GE14336Imported
ORF Names:Dyak_GE14336Imported, GE14336Imported
OrganismiDrosophila yakuba (Fruit fly)
Taxonomic identifieri7245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000002282: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0231950. Dyak\GE14336.

Interactioni

Protein-protein interaction databases

STRINGi7245.FBpp0259346.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
KOiK10747.
OrthoDBiEOG7RFTGN.
PhylomeDBiB4PA92.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4PA92-1 [UniParc]FASTAAdd to Basket

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MQKSITSFFK KQSDANDSAS PPKKVPKIDA KTELPDEPLI KSESASPETK    50
AKVEPMSVDS EEKTSPVKNV KTEPKDVEDK TTDKKVTTIG LNSTSATKED 100
MENYDPSADS YHPLKNAYWK DKKVTPYLAL ARTFQVIEET KGRLKMIDTL 150
SNFFCSVMLV SPDDLVPSVY LSINQLAPAY EGLELGVAET TLMKAICKAT 200
GRNLAHIKSQ THLIGDLGIV AEQSRVSQRM MFQPAPLNVR DVFRKLREIA 250
KISGQSKMDQ VYNMFVACRS SEARFFIRSL IGKLRIGIAE QSLLTALAVG 300
LVKKNHIDDC KASKVPEVYK DEIAETTLLL KTAYCQCPNY DIIIPAILKY 350
DIKELQERCP MHPGMPLRPM LAQPTKGVHE VFERFGGMQI TCEWKYDGER 400
AQIHRNEKGE ISIFSRNSEN NTAKYPDLIA RSAGLLKGDI KSYIIDSEIV 450
AWDVERKQIL PFQVLSTRKR KNVDIEEIKV QVCVYIFDLL YINGTALVTK 500
NLSERRKLLL EHFQEVEGEW KFATALDTND IDEVQQFLEE SIKGNCEGLM 550
VKTLDEEATY EIAKRSRNWL KLKKDYLSNV GDSLDLVVIG GYKGKGRRTG 600
TYGGFLLACY DTENEEYQSI CKIGTGFTDE DLQTHSEFLG KHVTSTAKSY 650
YRYDPSLEPD HWFEPVQVWE VKCADLSLSP IHRAAIGIVD GERGISLRFP 700
RFIRIRDDKN SENATDANQV AHMYQSQDQV KNNQKSSTQM EMEDEFY 747
Length:747
Mass (Da):84,685
Last modified:September 23, 2008 - v1
Checksum:iE04C6CA0EA0FB6EC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000158 Genomic DNA. Translation: EDW92418.1.
RefSeqiXP_002092706.1. XM_002092670.1.

Genome annotation databases

EnsemblMetazoaiFBtr0260854; FBpp0259346; FBgn0231950.
GeneIDi6531920.
KEGGidya:Dyak_GE14336.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CM000158 Genomic DNA. Translation: EDW92418.1 .
RefSeqi XP_002092706.1. XM_002092670.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7245.FBpp0259346.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0260854 ; FBpp0259346 ; FBgn0231950 .
GeneIDi 6531920.
KEGGi dya:Dyak_GE14336.

Organism-specific databases

FlyBasei FBgn0231950. Dyak\GE14336.

Phylogenomic databases

eggNOGi COG1793.
KOi K10747.
OrthoDBi EOG7RFTGN.
PhylomeDBi B4PA92.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tai18E2 / Tucson 14021-0261.01.
  2. "Principles of genome evolution in the Drosophila melanogaster species group."
    Ranz J.M., Maurin D., Chan Y.S., von Grotthuss M., Hillier L.W., Roote J., Ashburner M., Bergman C.M.
    PLoS Biol. 5:E152-E152(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiB4PA92_DROYA
AccessioniPrimary (citable) accession number: B4PA92
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 9, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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