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B4PA92

- B4PA92_DROYA

UniProt

B4PA92 - B4PA92_DROYA

Protein

DNA ligase

Gene

Dyak\GE14336

Organism
Drosophila yakuba (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Name:Dyak\GE14336Imported
    ORF Names:Dyak_GE14336Imported, GE14336Imported
    OrganismiDrosophila yakuba (Fruit fly)Imported
    Taxonomic identifieri7245 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000002282: Unassembled WGS sequence

    Organism-specific databases

    FlyBaseiFBgn0231950. Dyak\GE14336.

    Interactioni

    Protein-protein interaction databases

    STRINGi7245.FBpp0259346.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1793.
    KOiK10747.
    OrthoDBiEOG7RFTGN.
    PhylomeDBiB4PA92.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4PA92-1 [UniParc]FASTAAdd to Basket

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    MQKSITSFFK KQSDANDSAS PPKKVPKIDA KTELPDEPLI KSESASPETK    50
    AKVEPMSVDS EEKTSPVKNV KTEPKDVEDK TTDKKVTTIG LNSTSATKED 100
    MENYDPSADS YHPLKNAYWK DKKVTPYLAL ARTFQVIEET KGRLKMIDTL 150
    SNFFCSVMLV SPDDLVPSVY LSINQLAPAY EGLELGVAET TLMKAICKAT 200
    GRNLAHIKSQ THLIGDLGIV AEQSRVSQRM MFQPAPLNVR DVFRKLREIA 250
    KISGQSKMDQ VYNMFVACRS SEARFFIRSL IGKLRIGIAE QSLLTALAVG 300
    LVKKNHIDDC KASKVPEVYK DEIAETTLLL KTAYCQCPNY DIIIPAILKY 350
    DIKELQERCP MHPGMPLRPM LAQPTKGVHE VFERFGGMQI TCEWKYDGER 400
    AQIHRNEKGE ISIFSRNSEN NTAKYPDLIA RSAGLLKGDI KSYIIDSEIV 450
    AWDVERKQIL PFQVLSTRKR KNVDIEEIKV QVCVYIFDLL YINGTALVTK 500
    NLSERRKLLL EHFQEVEGEW KFATALDTND IDEVQQFLEE SIKGNCEGLM 550
    VKTLDEEATY EIAKRSRNWL KLKKDYLSNV GDSLDLVVIG GYKGKGRRTG 600
    TYGGFLLACY DTENEEYQSI CKIGTGFTDE DLQTHSEFLG KHVTSTAKSY 650
    YRYDPSLEPD HWFEPVQVWE VKCADLSLSP IHRAAIGIVD GERGISLRFP 700
    RFIRIRDDKN SENATDANQV AHMYQSQDQV KNNQKSSTQM EMEDEFY 747
    Length:747
    Mass (Da):84,685
    Last modified:September 23, 2008 - v1
    Checksum:iE04C6CA0EA0FB6EC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000158 Genomic DNA. Translation: EDW92418.1.
    RefSeqiXP_002092706.1. XM_002092670.1.

    Genome annotation databases

    EnsemblMetazoaiFBtr0260854; FBpp0259346; FBgn0231950.
    GeneIDi6531920.
    KEGGidya:Dyak_GE14336.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000158 Genomic DNA. Translation: EDW92418.1 .
    RefSeqi XP_002092706.1. XM_002092670.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7245.FBpp0259346.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0260854 ; FBpp0259346 ; FBgn0231950 .
    GeneIDi 6531920.
    KEGGi dya:Dyak_GE14336.

    Organism-specific databases

    FlyBasei FBgn0231950. Dyak\GE14336.

    Phylogenomic databases

    eggNOGi COG1793.
    KOi K10747.
    OrthoDBi EOG7RFTGN.
    PhylomeDBi B4PA92.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Tai18E2 / Tucson 14021-0261.01Imported.
    2. "Principles of genome evolution in the Drosophila melanogaster species group."
      Ranz J.M., Maurin D., Chan Y.S., von Grotthuss M., Hillier L.W., Roote J., Ashburner M., Bergman C.M.
      PLoS Biol. 5:E152-E152(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiB4PA92_DROYA
    AccessioniPrimary (citable) accession number: B4PA92
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3