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Protein

Angiotensin-converting enzyme

Gene

Dyak\GE18785

Organism
Drosophila yakuba (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.002.

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Dyak\GE18785Imported
ORF Names:Dyak_GE18785Imported, GE18785Imported
OrganismiDrosophila yakuba (Fruit fly)Imported
Taxonomic identifieri7245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000002282 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0236171. Dyak\GE18785.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500282048523 – 630Angiotensin-converting enzymeSequence analysisAdd BLAST608

Keywords - PTMi

GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0236171.

Interactioni

Protein-protein interaction databases

STRINGi7245.FBpp0263795.

Structurei

3D structure databases

ProteinModelPortaliB4NXF9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3690. Eukaryota.
ENOG410XPJ3. LUCA.
KOiK01283.
OMAiSAWDFYQ.
OrthoDBiEOG091G033S.
PhylomeDBiB4NXF9.

Family and domain databases

CDDicd06461. M2_ACE. 1 hit.
InterProiView protein in InterPro
IPR001548. Peptidase_M2.
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiView protein in Pfam
PF01401. Peptidase_M2. 1 hit.
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

B4NXF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGACNITVLL LVIMLWLPHG LSMGNSCSAS VLEARRFFEL ENEQLRRRFH
60 70 80 90 100
EEFLSGYNYN TNVTEANRQA MIDVYARNAE LNKRLAQQIK ASDYIQSEDA
110 120 130 140 150
DIRRQAEHLS KLGASALNAD DYLALQNAIS SMQTNYATAT VCSYTNRSDC
160 170 180 190 200
SLTLEPHIQE RLSHSRDPAE LAWYWREWHD KAGTPMRENF AEYVRLTRKA
210 220 230 240 250
SQLNGHRSYA DYWVQFYEDP DFERQLDATF KQLLPFYRQL HGYVRFRLRQ
260 270 280 290 300
HYGPDVMPAE GNIPISLLGN MWGQSWNELL DLFTPYPEKP FVDVKAEMEK
310 320 330 340 350
QGYTVQKLFE LGDQYFQSLG MRALPPSFWN LSLLTRPDDR QVVCHASAWD
360 370 380 390 400
FYQDSDVRIK MCTEVDSHYF YVVHHELGHI QYYLQYEQQP AVYRGAPNPG
410 420 430 440 450
FHEAVGDVIA LSVMSAKHLK AIGLLENGRL DEKSRINQLF KQALSKIVFL
460 470 480 490 500
PFGYAVDKYR HAVFRNELDE SQWNCGFWQM RSEFGGVEPP VFRTEKDFDP
510 520 530 540 550
PAKYHIDADV EYLRYFAAHI FQFQFHKALC RKAGQYAPNN SRLTLDNCDI
560 570 580 590 600
FGSKAAGRSL SQFLSKGNSR HWKEVLEEFT GETEMDPAAL LEYFEPLYQW
610 620 630
LKQENSRLGV PLGWGPTGKI PSDCCGTFST
Length:630
Mass (Da):72,963
Last modified:September 23, 2008 - v1
Checksum:i41258ED8EFFDFD61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000157 Genomic DNA. Translation: EDW88550.1.
RefSeqiXP_002088838.1. XM_002088802.2.

Genome annotation databases

EnsemblMetazoaiFBtr0265303; FBpp0263795; FBgn0236171.
GeneIDi6527758.
KEGGidya:Dyak_GE18785.

Similar proteinsi

Entry informationi

Entry nameiB4NXF9_DROYA
AccessioniPrimary (citable) accession number: B4NXF9
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: August 30, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported